Immunogenicity 6352
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
XIRP2
Transcript ID
NM_152381
HLA INFO
B*07:02
TCR INFO
No TCR info found!
Full length protein sequence (3549 aa)
MFPMQ
1
KGSLN
6
LLRQK
11
WESCD
16
YQRSE
21
CHPRD
26
SHCTI
31
FQPQE
36
SKLLA
41
PEGEV
46
VSAPQ
51
SLDPT
56
SLPYS
61
TGEEM
66
WSSKP
71
EEKDS
76
VDKSN
81
NTREY
86
GRPEV
91
LKEDS
96
LSSRR
101
RIERF
106
SIALD
111
ELRSV
116
FEAPK
121
SGNKP
126
AEYGG
131
KEVEI
136
ERSLC
141
SPAFK
146
SHPGS
151
QLEDS
156
VKDSD
161
KKGKE
166
TSFDK
171
MSPES
176
GHSRI
181
FEATA
186
GPNKP
191
ESGFA
196
EDSAA
201
RGEGV
206
SDLHE
211
VVSLK
216
ERMAR
221
YQAAV
226
SRGDC
231
RSFSA
236
NMMEE
241
SEMCA
246
VPGGL
251
AKVKK
256
QFEDE
261
ITSSR
266
NTFAQ
271
YQYQH
276
QNRSE
281
QEAIH
286
SSQVG
291
TSRSS
296
QEMAR
301
NEQEG
306
SKVQK
311
IDVHG
316
TEMVS
321
HLEKH
326
TEEVN
331
QASQF
336
HQYVQ
341
ETVID
346
TPEDE
351
EIPKV
356
STKLL
361
KEQFE
366
KSAQE
371
KILYS
376
DKEMT
381
TPAKQ
386
IKTES
391
EYEET
396
FKPSS
401
VVSTS
406
STSCV
411
STSQR
416
KETST
421
TRYSD
426
HSVTS
431
STLAQ
436
INATS
441
SGMTE
446
EFPPP
451
PPDVL
456
QTSVD
461
VTAFS
466
QSPEL
471
PSPPR
476
RLPVP
481
KDVYS
486
KQRNL
491
YELNR
496
LYKHI
501
HPELR
506
KNLEK
511
DYISE
516
VSEIV
521
SSQMN
526
SGSSV
531
SADVQ
536
QARYV
541
FENTN
546
DSSQK
551
DLNSE
556
REYLE
561
WDEIL
566
KGEVQ
571
SIRWI
576
FENQP
581
LDSIN
586
NGSPD
591
EGDIS
596
RGIAD
601
QEIIA
606
GGDVK
611
YTTWM
616
FETQP
621
IDTLG
626
AYSSD
631
TVENA
636
EKIPE
641
LARGD
646
VCTAR
651
WMFET
656
RPLDS
661
MNKMH
666
QSQEE
671
SAVTI
676
SKDIT
681
GGDVK
686
TVRYM
691
FETQH
696
LDQLG
701
QLHSV
706
DEVHL
711
LQLRS
716
ELKEI
721
KGNVK
726
RSIKC
731
FETQP
736
LYVIR
741
DGSGQ
746
MLEIK
751
TVHRE
756
DVEKG
761
DVRTA
766
RWMFE
771
TQPLD
776
TINKD
781
ITEIK
786
VVRGI
791
SMEEN
796
VKGGV
801
SKAKW
806
LFETQ
811
PLEKI
816
KESEE
821
VIIEK
826
EKIIG
831
TDVSR
836
KCWMF
841
ETQPL
846
DILKE
851
VPDAD
856
SLQRE
861
EIIGG
866
DVQTT
871
KHLFE
876
TLPIE
881
ALKDS
886
PDIGK
891
LQKIT
896
ASEEE
901
KGDVR
906
HQKWI
911
FETQP
916
LEDIR
921
KDKKE
926
YTRTV
931
KLEEV
936
DRGDV
941
KNYTH
946
IFESN
951
NLIKF
956
DASHK
961
IEVEG
966
VTRGA
971
VELNK
976
SLFET
981
TPLYA
986
IQDPL
991
GKYHQ
996
VKTVQ
1001
QEEIV
1006
RGDVR
1011
SCRWL
1016
FETRP
1021
IDQFD
1026
ESIHK
1031
FQIIR
1036
GISAQ
1041
EIQTG
1046
NVKSA
1051
KWLFE
1056
TQPLD
1061
SIKYF
1066
SDVEE
1071
TESKT
1076
EQTRD
1081
IVKGD
1086
VKTCK
1091
WLFET
1096
QPMES
1101
LYEKV
1106
SLMTS
1111
SEEIH
1116
KGDVK
1121
TCTWL
1126
FETQP
1131
LDTIK
1136
DDSET
1141
AVKLQ
1146
TVKQE
1151
EIQGG
1156
DVRTA
1161
CFLFE
1166
TENLD
1171
SIQGE
1176
EVKEI
1181
KPVEM
1186
DIQAG
1191
DVSSM
1196
RYKFE
1201
NQSLD
1206
SISSS
1211
SEEVL
1216
KKIKT
1221
LKTED
1226
IQKGN
1231
VLNCR
1236
WLFEN
1241
QPIDK
1246
IKESQ
1251
EGDEC
1256
VKTVT
1261
DIQGG
1266
DVRKG
1271
CFIFE
1276
TFSLD
1281
EIKEE
1286
SDYIS
1291
TKKTI
1296
TEEVI
1301
QGDVK
1306
SYRML
1311
FETQP
1316
LYAIQ
1321
DREGS
1326
YHEVT
1331
TVKKE
1336
EVIHG
1341
DVRGT
1346
RWLFE
1351
TKPLD
1356
SINKS
1361
ETVYV
1366
IKSVT
1371
QEDIQ
1376
KGDVS
1381
SVRYR
1386
FETQP
1391
LDQIS
1396
EESHN
1401
IMPSI
1406
DHIQG
1411
GNVKT
1416
SRQFF
1421
ESENF
1426
DKNNY
1431
IRTVS
1436
VNEIQ
1441
KGNVK
1446
TSTWL
1451
FETHT
1456
MDELR
1461
GEGLE
1466
YENIK
1471
TVTQE
1476
DVQKG
1481
DVKQA
1486
VWLFE
1491
NRTFD
1496
SIMEA
1501
HKGIT
1506
KMTKE
1511
EIPPS
1516
DVKTT
1521
TWLFE
1526
TTPLH
1531
EFNET
1536
RVEKI
1541
EIIGK
1546
SIKET
1551
LEDLY
1556
SQKVI
1561
QAPGI
1566
IIEAD
1571
EIGDV
1576
RMAKY
1581
KLMNQ
1586
ASPEI
1591
QKEEI
1596
IRADL
1601
RNIMV
1606
NLLSK
1611
RDCTE
1616
REILI
1621
SEEEK
1626
GNVNL
1631
TKTQL
1636
LNRST
1641
EFHAE
1646
KEEIV
1651
KGDVQ
1656
QAIKN
1661
LFSEE
1666
RSVKK
1671
GILIQ
1676
EDEKG
1681
DINMT
1686
IYCLL
1691
HENDG
1696
DTIER
1701
EEVIG
1706
GDVKR
1711
TIHNL
1716
LSSTS
1721
NNKIS
1726
ERAKI
1731
DASER
1736
GNVQF
1741
FTTCI
1746
EAGAL
1751
DYLKQ
1756
LHTES
1761
NETLT
1766
AKKQE
1771
GEKEI
1776
IGGDV
1781
EGTKL
1786
LLKKR
1791
QSLVE
1796
RTVSE
1801
TDIIP
1806
GDVHN
1811
TVKVF
1816
MTEPQ
1821
STFGK
1826
IPKEE
1831
IIKGD
1836
LTSTL
1841
NSLSQ
1846
AVNQK
1851
TVTKT
1856
EEIIK
1861
GNMLA
1866
TLKSL
1871
KESSH
1876
RWKES
1881
KQPDA
1886
IPGDI
1891
EKAIE
1896
CLEKA
1901
TNTKT
1906
EILKK
1911
ELLKD
1916
DLETS
1921
LRSLK
1926
EAQRS
1931
FKEVH
1936
KEGVI
1941
KKDAK
1946
AVMAG
1951
SSGEQ
1956
KTDIH
1961
QVAVQ
1966
RNKNS
1971
LLQPK
1976
PGPFE
1981
PAAKW
1986
QGGAD
1991
TLSQT
1996
MGKSC
2001
HGNLV
2006
EERTE
2011
VNLPK
2016
APKGT
2021
VKIVI
2026
DREQN
2031
NDALE
2036
KSLRR
2041
LSNSH
2046
HKSNV
2051
LESGD
2056
KTGVW
2061
TDTTG
2066
EQHLR
2071
DEYMS
2076
RQLTS
2081
TVSVK
2086
NNLTT
2091
KESDR
2096
AVREL
2101
KKDDV
2106
FNSIQ
2111
SAGKT
2116
VGKQQ
2121
TYELR
2126
NDHQK
2131
MEGFH
2136
IKSPK
2141
KTKNI
2146
KILTD
2151
TQSSK
2156
PSPTQ
2161
HPVSM
2166
PVGGT
2171
YDLSG
2176
DFQKQ
2181
TLLKQ
2186
ETKYS
2191
NKDIK
2196
KKNIN
2201
LQPMW
2206
QLLPV
2211
EQDTS
2216
NVTEM
2221
KVSEK
2226
SHNTF
2231
KATNK
2236
KRETD
2241
VHLKS
2246
QDFLM
2251
KTNTS
2256
TGLKM
2261
AMERS
2266
LNPIN
2271
FNPEN
2276
NVKES
2281
ECPLP
2286
PPSPP
2291
PPPPS
2296
NASSE
2301
IEFPL
2306
PPPPP
2311
LMMFP
2316
EKNGF
2321
LPSLS
2326
TEKIK
2331
AEFES
2336
FPGLP
2341
LPPPP
2346
VDEKS
2351
ERESS
2356
SMFLP
2361
PPPPP
2366
TPSQK
2371
PAHLL
2376
SSSAP
2381
EKHSG
2386
DFMQQ
2391
YSQKE
2396
ASNSQ
2401
NSQAK
2406
IITGK
2411
TGVLP
2416
PPTLP
2421
KPKLP
2426
KHIKD
2431
NKNDF
2436
SPKVE
2441
LATSL
2446
SDMEC
2451
KITTS
2456
KDQKK
2461
VMVMT
2466
SSEHT
2471
ETKQN
2476
VISKS
2481
LDERK
2486
QLSID
2491
SANCL
2496
SHTVP
2501
GTSAP
2506
RKKQI
2511
APLIK
2516
SHSFP
2521
ESSGQ
2526
QNPKP
2531
YMRKF
2536
KTPLM
2541
IAEEK
2546
YRQQK
2551
EEIEK
2556
QKQES
2561
SYYNI
2566
VKTQS
2571
QNQHI
2576
TEVEK
2581
EMPLQ
2586
KTNEE
2591
VSLSG
2596
IDSEC
2601
TVVQP
2606
SPGSQ
2611
SNARI
2616
LGVCS
2621
DNQLS
2626
TTSPE
2631
TVAAK
2636
RLHHV
2641
LAASE
2646
DKDKM
2651
KKEVL
2656
QSSRD
2661
IMQSK
2666
SACEI
2671
KQSHQ
2676
ECSTQ
2681
QTQQK
2686
KYLEQ
2691
LHLPQ
2696
SKPIS
2701
PNFKV
2706
KTIKL
2711
PTLDH
2716
TLNET
2721
DHSYE
2726
SHKQQ
2731
SEIDV
2736
QTFTK
2741
KQYLK
2746
TKKTE
2751
ASTEC
2756
SHKQS
2761
LAERH
2766
YQLPK
2771
KEKRV
2776
TVQLP
2781
TESIQ
2786
KNQED
2791
KLKMV
2796
PRKQR
2801
EFSGS
2806
DRGKL
2811
PGSEE
2816
KNQGP
2821
SMIGR
2826
KEERL
2831
ITERK
2836
HEHLK
2841
NKSAP
2846
KVVKQ
2851
KVIDA
2856
HLDSQ
2861
TQNFQ
2866
QTQIQ
2871
TAESK
2876
AEHKK
2881
LPQPY
2886
NSLQE
2891
EKCLE
2896
VKGIQ
2901
EKQVF
2906
SNTKD
2911
SKQEI
2916
TQNKS
2921
FFSSV
2926
KESQR
2931
DDGKG
2936
ALNIV
2941
EFLRK
2946
REELQ
2951
QILSR
2956
VKQFE
2961
AEPNK
2966
SGLKT
2971
FQTLL
2976
NTIPG
2981
WLISE
2986
DKREY
2991
AVHIA
2996
MENNL
3001
EKVKE
3006
EITHI
3011
KTQAE
3016
DMLVS
3021
YENII
3026
QTAMM
3031
SSKTG
3036
KPGNK
3041
PTSLD
3046
ETSSK
3051
VSNVH
3056
VSNNK
3061
NSEQK
3066
ENKIA
3071
KEKTV
3076
QHQVA
3081
AHHEA
3086
TVRSH
3091
VKTHQ
3096
EIKLD
3101
DSNIP
3106
PPSLK
3111
TRPPS
3116
PTFIT
3121
IESTA
3126
RRTEN
3131
PTKNE
3136
LSQSP
3141
KKDSY
3146
VEPPP
3151
RRPMS
3156
QKSEI
3161
HRANT
3166
SPSPP
3171
RSRSE
3176
QLVRL
3181
KDTTA
3186
KLSKG
3191
AIPCP
3196
AATPV
3201
PIVEK
3206
RSEII
3211
MSPAT
3216
LRRQI
3221
KIETR
3226
GRDSP
3231
PTITI
3236
PVNIN
3241
HAASG
3246
SFRES
3251
VDAQE
3256
EIRKV
3261
EKRAT
3266
YVHKD
3271
GLNST
3276
DHMVP
3281
DTESY
3286
DAVEI
3291
IRKVA
3296
VPPRL
3301
SEHTQ
3306
RYEAA
3311
NRTVQ
3316
MAENF
3321
VNDPE
3326
NEINR
3331
WFREF
3336
EHGPV
3341
SEAKS
3346
NRRVY
3351
AKGET
3356
NHNIQ
3361
QESRT
3366
FCKEE
3371
FGLTS
3376
LGNTS
3381
FTDFS
3386
CKHPR
3391
ELREK
3396
IPVKQ
3401
PRICS
3406
ETRSL
3411
SEHFS
3416
GMDAF
3421
ESQIV
3426
ESKMK
3431
TSSSH
3436
SSEAG
3441
KSGCD
3446
FKHAP
3451
PTYED
3456
VIAGH
3461
ILDIS
3466
DSPKE
3471
VRKNF
3476
QKTWQ
3481
ESGRV
3486
FKGLG
3491
YATAD
3496
ASATE
3501
MRTTF
3506
QEESA
3511
FISEA
3516
AAPRQ
3521
GNMYT
3526
LSKDS
3531
LSNGV
3536
PSGRQ
3541
AEFS
3546
Mutation Information
DNA mutation:
None
Peptide Range:
797 ~ 821
Mut AA position:
809 (13 in Wild Type peptide)
Alignment
Wild Type:
"MEENVKGGVSKAKWLFETQPLEKIK
||||||||||||.||||||||||||
Mutant:
MEENVKGGVSKAMWLFETQPLEKIK"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) XIRP2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay