Immunogenicity 6362

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MGAT1
Transcript ID
NM_001114618
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (445 aa)
MLKKQ
1
SAGLV
6
LWGAI
11
LFVAW
16
NALLL
21
LFFWT
26
RPAPG
31
RPPSV
36
SALDG
41
DPASL
46
TREVI
51
RLAQD
56
AEVEL
61
ERQRG
66
LLQQI
71
GDALS
76
SQRGR
81
VPTAA
86
PPAQP
91
RVPVT
96
PAPAV
101
IPILV
106
IACDR
111
STVRR
116
CLDKL
121
LHYRP
126
SAELF
131
PIIVS
136
QDCGH
141
EETAQ
146
AIASY
151
GSAVT
156
HIRQP
161
DLSSI
166
AVPPD
171
HRKFQ
176
GYYKI
181
ARHYR
186
WALGQ
191
VFRQF
196
RFPAA
201
VVVED
206
DLEVA
211
PDFFE
216
YFRAT
221
YPLLK
226
ADPSL
231
WCVSA
236
WNDNG
241
KEQMV
246
DASRP
251
ELLYR
256
TDFFP
261
GLGWL
266
LLAEL
271
WAELE
276
PKWPK
281
AFWDD
286
WMRRP
291
EQRQG
296
RACIR
301
PEISR
306
TMTFG
311
RKGVS
316
HGQFF
321
DQHLK
326
FIKLN
331
QQFVH
336
FTQLD
341
LSYLQ
346
REAYD
351
RDFLA
356
RVYGA
361
PQLQV
366
EKVRT
371
NDRKE
376
LGEVR
381
VQYTG
386
RDSFK
391
AFAKA
396
LGVMD
401
DLKSG
406
VPRAG
411
YRGIV
416
TFQFR
421
GRRVH
426
LAPPL
431
TWEGY
436
DPSWN
441
Mutation Information
DNA mutation:
None
Peptide Range:
34 ~ 58
Mut AA position:
46 (13 in Wild Type peptide)
Alignment
Wild Type:
"PGRPPSVSALDGDPASLTREVIRLA
||||||||||||.||||||||||||
Mutant:
PGRPPSVSALDGAPASLTREVIRLA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MGAT1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay