Immunogenicity 6370

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZSCAN1
Transcript ID
NM_182572
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (408 aa)
MLPRP
1
KAPAS
6
PRRPQ
11
TPTPS
16
EQDAD
21
PGPAS
26
PRDTE
31
AQRLR
36
FRQFQ
41
YHVAS
46
GPHLA
51
LGQLW
56
TLCRQ
61
WLRPE
66
ARSKE
71
QMLEL
76
LVLEQ
81
FLGAL
86
PSKMR
91
TWVQS
96
QGPRS
101
CREAA
106
SLVED
111
LTQMC
116
QQEVL
121
VSLDS
126
VEPQD
131
WSFGE
136
EEDGK
141
SPRSQ
146
KEPSQ
151
ASELI
156
LDAVA
161
AAPAL
166
PEESE
171
WLETT
176
QLQQS
181
LHTRA
186
EAEAP
191
RAPGL
196
LGSRA
201
RLPLK
206
PSIWD
211
EPEDL
216
LAGPS
221
SDLRA
226
EGTVI
231
SSPKG
236
PSAQR
241
ISPRR
246
RNRNT
251
DQSGR
256
HQPSL
261
KHTKG
266
GTQEA
271
VAGIS
276
VVPRG
281
PRGGR
286
PFQCA
291
DCGMV
296
FTWVT
301
HFIEH
306
QKTHR
311
EEGPF
316
PCPEC
321
GKVFL
326
HNSVL
331
TEHGK
336
IHLLE
341
PPRKK
346
APRSK
351
GPRES
356
VPPRD
361
GAQGP
366
VAPRS
371
PKRPF
376
QCSVC
381
GKAFP
386
WMVHL
391
IDHQK
396
LHTAH
401
GHM
406
Mutation Information
DNA mutation:
None
Peptide Range:
30 ~ 54
Mut AA position:
42 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPRDTEAQRLRFRQFQYHVASGPHL
||||||||||||.||||||||||||
Mutant:
SPRDTEAQRLRFQQFQYHVASGPHL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZSCAN1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay