Immunogenicity 6413
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
RADIL
Transcript ID
NM_018059
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1075 aa)
MFYGT
1
HFIMS
6
PPTKS
11
KLKRQ
16
SQLLS
21
SMLSR
26
TLSYK
31
YRDLD
36
STFSS
41
LGASD
46
DPAEL
51
STQLS
56
APGVL
61
KVFGD
66
SVCTG
71
THYKS
76
VLATG
81
TSSAR
86
ELVKE
91
ALERY
96
ALDPR
101
QAGQY
106
VLCDV
111
VGQAG
116
DAGQR
121
WQARC
126
FRVFG
131
DSEKP
136
LLIQE
141
LWKPR
146
EGLSR
151
RFELR
156
KRSDV
161
EELAA
166
KEVDT
171
ITAGI
176
NAQAR
181
RLQRS
186
RAKGT
191
PTPAL
196
GDARS
201
SPPPR
206
LRRTV
211
SETSL
216
SPVNA
221
LPAAA
226
QGPEE
231
PGPDA
236
MRYSL
241
YQSPH
246
LLLLQ
251
GYSQQ
256
HDSLV
261
YVLNR
266
DRHTV
271
GQRTP
276
SSKPS
281
ISLSA
286
PDILP
291
LHCTI
296
RRQPL
301
PDSGQ
306
AAGRL
311
VLEPI
316
PGAHI
321
SVNFS
326
EVGHR
331
TVVLH
336
HGDLL
341
SLGLY
346
YLLLF
351
KDPAQ
356
AQPLP
361
ARALA
366
RLRAV
371
PQSCR
376
LCGAA
381
LGARG
386
AASPT
391
QAALP
396
RRQQL
401
LLEFE
406
PHLED
411
TLLQR
416
IMTLI
421
EPGGD
426
DHKLT
431
PAFLL
436
CLCIQ
441
HSATH
446
FQPGT
451
FGQLL
456
LKIAR
461
LIRET
466
VWEKT
471
KELAE
476
KQAQL
481
QEPIS
486
LASCA
491
MADLV
496
PDLQP
501
ILFWM
506
SNSIE
511
LLYFI
516
QQKCP
521
LYMQS
526
MEEQL
531
DITGS
536
KESLF
541
SCTLT
546
ASEEA
551
MAVLE
556
EVVLY
561
AFQQC
566
VYYVS
571
KSLYI
576
CLPAL
581
LECPP
586
FQTER
591
RESWS
596
SAPEL
601
PEELR
606
RVVSV
611
YQAAL
616
DLLRQ
621
LQVHP
626
EVASQ
631
MLAYL
636
FFFSG
641
TLLLN
646
QLLDR
651
GPSLS
656
CFHWP
661
RGVQA
666
CARLQ
671
QLLEW
676
MRSAG
681
FGAAG
686
EHFFQ
691
KLSCT
696
LNLLA
701
TPRAQ
706
LIQMS
711
WTALR
716
AAFPA
721
LSPAQ
726
LHRLL
731
THYQL
736
ASAMG
741
PMSTW
746
EPGAQ
751
DSPEA
756
FRSED
761
VLESY
766
ENPPP
771
IVLPS
776
DGFQV
781
DLEAN
786
CLDDS
791
IYQHL
796
LYVRH
801
FLWGL
806
RSRAS
811
PGSPG
816
RPGSG
821
ASQPV
826
CPEGM
831
HHVVL
836
DGHLE
841
APSCP
846
LAPRD
851
PGPAA
856
REVAP
861
ERTLP
866
LRGAP
871
WAQAP
876
PGRQP
881
SRGGS
886
QAGPP
891
HTDSS
896
CLLTP
901
PSTPL
906
GPEPG
911
DPDWP
916
ESGGP
921
CGKAL
926
PERQR
931
NGLSG
936
LRGAA
941
PEGDS
946
AALAE
951
ESPPA
956
PSSRS
961
SSTED
966
FCYVF
971
TVELE
976
RGPSG
981
LGMGL
986
IDGMH
991
THLGA
996
PGLYI
1001
QTLLP
1006
GSPAA
1011
ADGRL
1016
SLGDR
1021
ILEVN
1026
GSSLL
1031
GLGYL
1036
RAVDL
1041
IRHGG
1046
KKMRF
1051
LVAKS
1056
DVETA
1061
KKIHF
1066
RTPPL
1071
Mutation Information
DNA mutation:
None
Peptide Range:
389 ~ 413
Mut AA position:
401 (13 in Wild Type peptide)
Alignment
Wild Type:
"RGAASPTQAALPRRQQLLLEFEPHL
||||||||||||.||||||||||||
Mutant:
RGAASPTQAALPWRQQLLLEFEPHL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) RADIL
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay