Immunogenicity 6434

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GPHN
Transcript ID
NM_020806
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (769 aa)
MATEG
1
MILTN
6
HDHQI
11
RVGVL
16
TVSDS
21
CFRNL
26
AEDRS
31
GINLK
36
DLVQD
41
PSLLG
46
GTISA
51
YKIVP
56
DEIEE
61
IKETL
66
IDWCD
71
EKELN
76
LILTT
81
GGTGF
86
APRDV
91
TPEAT
96
KEVIE
101
REAPG
106
MALAM
111
LMGSL
116
NVTPL
121
GMLSR
126
PVCGI
131
RGKTL
136
IINLP
141
GSKKG
146
SQECF
151
QFILP
156
ALPHA
161
IDLLR
166
DAIVK
171
VKEVH
176
DELED
181
LPSPP
186
PPLSP
191
PPTTS
196
PHKQT
201
EDKGV
206
QCEEE
211
EEEKK
216
DSGVA
221
STEDS
226
SSSHI
231
TAAAI
236
AAKKH
241
PFYTS
246
PAVVM
251
AHGEQ
256
PIPGL
261
INYSH
266
HSTDE
271
RIPDS
276
IISRG
281
VQVLP
286
RDTAS
291
LSTTP
296
SESPR
301
AQATS
306
RLSTA
311
SCPTP
316
KVQSR
321
CSSKE
326
NILRA
331
SHSAV
336
DITKV
341
ARRHR
346
MSPFP
351
LTSMD
356
KAFIT
361
VLEMT
366
PVLGT
371
EIINY
376
RDGMG
381
RVLAQ
386
DVYAK
391
DNLPP
396
FPASV
401
KDGYA
406
VRAAD
411
GPGDR
416
FIIGE
421
SQAGE
426
QPTQT
431
VMPGQ
436
VMRVT
441
TGAPI
446
PCGAD
451
AVVQV
456
EDTEL
461
IRESD
466
DGTEE
471
LEVRI
476
LVQAR
481
PGQDI
486
RPIGH
491
DIKRG
496
ECVLA
501
KGTHM
506
GPSEI
511
GLLAT
516
VGVTE
521
VEVNK
526
FPVVA
531
VMSTG
536
NELLN
541
PEDDL
546
LPGKI
551
RDSNR
556
STLLA
561
TIQEH
566
GYPTI
571
NLGIV
576
GDNPD
581
DLLNA
586
LNEGI
591
SRADV
596
IITSG
601
GVSMG
606
EKDYL
611
KQVLD
616
IDLHA
621
QIHFG
626
RVFMK
631
PGLPT
636
TFATL
641
DIDGV
646
RKIIF
651
ALPGN
656
PVSAV
661
VTCNL
666
FVVPA
671
LRKMQ
676
GILDP
681
RPTII
686
KARLS
691
CDVKL
696
DPRPE
701
YHRCI
706
LTWHH
711
QEPLP
716
WAQST
721
GNQMS
726
SRLMS
731
MRSAN
736
GLLML
741
PPKTE
746
QYVEL
751
HKGEV
756
VDVMV
761
IGRL
766
Mutation Information
DNA mutation:
None
Peptide Range:
427 ~ 451
Mut AA position:
439 (13 in Wild Type peptide)
Alignment
Wild Type:
"QAGEQPTQTVMPGQVMRVTTGAPIP
||||||||||||.||||||||||||
Mutant:
QAGEQPTQTVMPEQVMRVTTGAPIP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GPHN

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay