Immunogenicity 6455

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
FYB2
Transcript ID
NM_001004303
HLA INFO
A*25:01
TCR INFO

No TCR info found!

T cell Tumor cell A*25:01
sequence
Full length protein sequence (728 aa)
MEGEG
1
VRNFK
6
ELRAK
11
FQNLD
16
APPLP
21
GPIKF
26
PAGVS
31
PKGDI
36
GGTQS
41
TQILA
46
NGKPL
51
SSNHK
56
QRTPY
61
CSSSE
66
SQPLQ
71
PQKIK
76
LAQKS
81
EIPKC
86
SNSPG
91
PLGKS
96
TVCSA
101
TSSQK
106
ASLLL
111
EVTQS
116
NVEII
121
TKEKV
126
MVANS
131
FRNKL
136
WNWEK
141
VSSQK
146
SEMSS
151
ALLLA
156
NYGSK
161
AIHLE
166
GQKGM
171
GLTPE
176
EPRKK
181
LETKG
186
AQTLP
191
SQKHV
196
VAPKI
201
LHNVS
206
EDPSF
211
VISQH
216
IRKSW
221
ENPPP
226
ERSPA
231
SSPCQ
236
PIYEC
241
ELASQ
246
APEKQ
251
PDVRH
256
HHLPK
261
TKPLP
266
SIDSL
271
GPPPP
276
KPSRP
281
PIVNL
286
QAFQR
291
QPAAV
296
PKTQG
301
EVTVE
306
EGSLS
311
PERLF
316
NAEFE
321
EPHNY
326
EATIS
331
YLRHS
336
GNSIN
341
LCTAK
346
EIADP
351
TYEVG
356
IEELQ
361
KPGKN
366
FPYPE
371
PSAKH
376
EDKKM
381
KEKQP
386
CELKP
391
KNTEK
396
EPYSN
401
HVFKV
406
DACEG
411
TPEKI
416
QMTNV
421
HTGRR
426
NMLAG
431
KQEAM
436
IDIIQ
441
TNPCP
446
EGPKL
451
ARHSQ
456
GHCGH
461
LEVLE
466
STKET
471
PDLGV
476
SKTSS
481
ISEEI
486
YDDVE
491
YSRKE
496
VPKLN
501
YSSSL
506
ASSSE
511
ENREL
516
YEDVY
521
KTKNN
526
YPKID
531
LDGKE
536
ALKRL
541
QQFFK
546
KEKDR
551
FKIKK
556
TKSKE
561
NLSAF
566
SILLP
571
DLELK
576
SQEVI
581
IYDDV
586
DLSEK
591
ESKDE
596
DKLKM
601
WKPKF
606
LTPKE
611
KKEKN
616
GAEES
621
ESFSP
626
RNFFK
631
TKKQN
636
LEKNR
641
MKREE
646
KLFRE
651
RFKYD
656
KEIIV
661
INTAV
666
ACSNN
671
SRNGI
676
FDLPI
681
SPGEE
686
LEVID
691
TTEQN
696
LVICR
701
NSKGK
706
YGYVL
711
IEHLD
716
FKHQS
721
WSP
726
Mutation Information
DNA mutation:
None
Peptide Range:
250 ~ 274
Mut AA position:
262 (13 in Wild Type peptide)
Alignment
Wild Type:
"QAPEKQPDVRHHHLPKTKPLPSIDS
||||||||||||.||||||||||||
Mutant:
QAPEKQPDVRHHNLPKTKPLPSIDS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) C1orf168

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay