Immunogenicity 6465

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
BLNK
Transcript ID
NM_001114094
HLA INFO
A*25:01
TCR INFO

No TCR info found!

T cell Tumor cell A*25:01
sequence
Full length protein sequence (433 aa)
MDKLN
1
KITVP
6
ASQKL
11
RQLQK
16
MVHDI
21
KNNEG
26
GIMNK
31
IKKLK
36
VKAPP
41
SVPRR
46
DYASE
51
SPADE
56
EEQWS
61
DDFDS
66
DYENP
71
DEHSD
76
SEMYV
81
MPAEE
86
NADDS
91
YEPPP
96
VEQET
101
RPVHP
106
ALPFA
111
RGEYI
116
DNRSS
121
QRHSP
126
PFSKT
131
LPSKP
136
SWPSE
141
KARLT
146
STLPA
151
LTALQ
156
KPQVP
161
PKPKG
166
LLEDE
171
ADYVV
176
PVEDN
181
DENYI
186
HPTES
191
SSPPP
196
EKGRN
201
SGAWE
206
TKSPP
211
PAAPS
216
PLPRA
221
GKKPT
226
TPLKT
231
TPVAS
236
QQNAS
241
SVCEE
246
KPIPA
251
ERHRG
256
SSHRQ
261
EAVQS
266
PVFPP
271
AQKQI
276
HQKPI
281
PLPRF
286
TEGGN
291
PTVDG
296
PLPSF
301
SSNST
306
ISEQE
311
AGVLC
316
KPWYA
321
GACDR
326
KSAEE
331
ALHRS
336
NKDGS
341
FLIRK
346
SSGHD
351
SKQPY
356
TLVVF
361
FNKRV
366
YNIPV
371
RFIEA
376
TKQYA
381
LGRKK
386
NGEEY
391
FGSVA
396
EIIRN
401
HQHSP
406
LVLID
411
SQNNT
416
KDSTR
421
LKYAV
426
KVS
431
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 21
Mut AA position:
9 (9 in Wild Type peptide)
Alignment
Wild Type:
"MDKLNKITVPASQKLRQLQKMVHDI
||||||||.||||||||||||
Mutant:
MDKLNKITAPASQKLRQLQKM----"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) BLNK

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay