Immunogenicity 647
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
IFNGR1
Transcript ID
ENST00000543628
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (461 aa)
MPTPT
1
NVTIE
6
SYNMN
11
PIVYW
16
EYQIM
21
PQVPV
26
FTVEV
31
KNYGV
36
KNSEW
41
IDACI
46
NISHH
51
YCNIS
56
DHVGD
61
PSNSL
66
WVRVK
71
ARVGQ
76
KESAY
81
AKSEE
86
FAVCR
91
DGKIG
96
PPKLD
101
IRKEE
106
KQIMI
111
DIFHP
116
SVFVN
121
GDEQE
126
VDYDP
131
ETTCY
136
IRVYN
141
VYVRM
146
NGSEI
151
QYKIL
156
TQKED
161
DCDEI
166
QCQLA
171
IPVSS
176
LNSQY
181
CVSAE
186
GVLHV
191
WGVTT
196
EKSKE
201
VCITI
206
FNSSI
211
KGSLW
216
IPVVA
221
ALLLF
226
LVLSL
231
VFICF
236
YIKKI
241
NPLKE
246
KSIIL
251
PKSLI
256
SVVRS
261
ATLET
266
KPESK
271
YVSLI
276
TSYQP
281
FSLEK
286
EVVCE
291
EPLSP
296
ATVPG
301
MHTED
306
NPGKV
311
EHTEE
316
LSSIT
321
EVVTT
326
EENIP
331
DVVPG
336
SHLTP
341
IERES
346
SSPLS
351
SNQSE
356
PGSIA
361
LNSYH
366
SRNCS
371
ESDHS
376
RNGFD
381
TDSSC
386
LESHS
391
SLSDS
396
EFPPN
401
NKGEI
406
KTEGQ
411
ELITV
416
IKAPT
421
SFGYD
426
KPHVL
431
VDLLV
436
DDSGK
441
ESLIG
446
YRPTE
451
DSKEF
456
S
461
Mutation Information
DNA mutation:
None
Peptide Range:
231 ~ 255
Mut AA position:
243 (13 in Wild Type peptide)
Alignment
Wild Type:
"LVLSLVFICFYIKKINPLKEKSIIL
||||||||||||.||||||||||||
Mutant:
LVLSLVFICFYIRKINPLKEKSIIL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) IFNGR1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay