Immunogenicity 6504

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SWT1
Transcript ID
NM_017673
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (900 aa)
MSSKE
1
SCGKK
6
ETSQR
11
KDTTT
16
SSPNF
21
GEKDK
26
KERKT
31
PASST
36
SSSSI
41
RSVSS
46
EKRKL
51
KSDHT
56
DVLYY
61
NIKRR
66
QGLKR
71
LSVEI
76
DTLRR
81
RPKIG
86
SSSQR
91
PIKLK
96
EASYS
101
NDNQI
106
ILQSP
111
SSNGT
116
KKDIH
121
KCVDF
126
KPKDI
131
KLTNA
136
GSKLD
141
HGIKS
146
LSSPK
151
IASDV
156
KPKAE
161
GQASE
166
NKWSH
171
LLVQR
176
EKMKE
181
LKKGR
186
NSKFR
191
DNSEK
196
CVLEK
201
WKRNQ
206
FSQDY
211
NSNKI
216
IKEPL
221
GSRRQ
226
KISFK
231
IPIKS
236
RDTLQ
241
KLVEE
246
NVFNI
251
DSNNS
256
KTKQE
261
EREYL
266
ESSQV
271
SLNVT
276
RQKTE
281
HLLSD
286
FTYKR
291
TVHEW
296
KRKHH
301
YDHQE
306
SNDSH
311
SRENL
316
TQSFE
321
APCCS
326
VSSES
331
IQDAD
336
QEMQI
341
VEELH
346
AARVG
351
KSVDL
356
PGELM
361
SMEID
366
LEDDV
371
HSSSA
376
NNTSD
381
RKLLI
386
VIDTN
391
ILMNH
396
LKFVR
401
ILKTT
406
EVPGF
411
DKLVL
416
IIPWV
421
VMQEL
426
DRMKE
431
GKLLK
436
RAQHK
441
AIPAV
446
HFIND
451
SLKNQ
456
DRKLW
461
GQSIQ
466
LASQK
471
HYGLS
476
DENND
481
DRVLK
486
CCLQH
491
QELFP
496
CSFVI
501
LCTDD
506
RNLRN
511
KGLIS
516
GVKSL
521
SKEEL
526
SAELL
531
HLSLN
536
TDVCH
541
QPCIP
546
KQQLK
551
AETTP
556
LKESY
561
KEEST
566
NSGLS
571
ILLES
576
IVSDL
581
EKSLG
586
TGLSS
591
ILETE
596
MKIAF
601
GNLWM
606
EILYL
611
KPPWT
616
LLHLL
621
QCFKK
626
HWLAV
631
FGLVM
636
EKNLL
641
LTIES
646
LYKNL
651
RKANK
656
AVDFT
661
TVKFL
666
LQDSR
671
SLLHA
676
FSTRS
681
NYDGI
686
LPQTF
691
AQVNN
696
LLQTF
701
AEVKT
706
KLKPN
711
SSENT
716
VTKKQ
721
EGTSL
726
KNSHN
731
QEITV
736
FSSSH
741
LPQPS
746
RHQEI
751
WSILE
756
SVWIT
761
IYQNS
766
TDVFQ
771
RLGSN
776
SALTT
781
SNIAS
786
FEEAF
791
ICLQK
796
LMAAV
801
RDILE
806
GIQRI
811
LAPNS
816
NYQDV
821
ETLYN
826
FLIKY
831
EVNKN
836
VKFTA
841
QEIYD
846
CVSQT
851
EYREK
856
LTIGC
861
RQLVE
866
MEYTM
871
QQCNA
876
SVYME
881
AKNRG
886
WCEDM
891
LNYRI
896
Mutation Information
DNA mutation:
None
Peptide Range:
244 ~ 268
Mut AA position:
256 (13 in Wild Type peptide)
Alignment
Wild Type:
"LQKLVEENVFNIDSNNSKTKQEERE
||||||||||||.||||||||||||
Mutant:
LQKLVEENVFNIYSNNSKTKQEERE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SWT1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay