Immunogenicity 6507

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TRIM28
Transcript ID
NM_005762
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (835 aa)
MAASA
1
AAASA
6
AAASA
11
ASGSP
16
GPGEG
21
SAGGE
26
KRSTA
31
PSAAA
36
SASAS
41
AAASS
46
PAGGG
51
AEALE
56
LLEHC
61
GVCRE
66
RLRPE
71
REPRL
76
LPCLH
81
SACSA
86
CLGPA
91
APAAA
96
NSSGD
101
GGAAG
106
DGTVV
111
DCPVC
116
KQQCF
121
SKDIV
126
ENYFM
131
RDSGS
136
KAATD
141
AQDAN
146
QCCTS
151
CEDNA
156
PATSY
161
CVECS
166
EPLCE
171
TCVEA
176
HQRVK
181
YTKDH
186
TVRST
191
GPAKS
196
RDGER
201
TVYCN
206
VHKHE
211
PLVLF
216
CESCD
221
TLTCR
226
DCQLN
231
AHKDH
236
QYQFL
241
EDAVR
246
NQRKL
251
LASLV
256
KRLGD
261
KHATL
266
QKSTK
271
EVRSS
276
IRQVS
281
DVQKR
286
VQVDV
291
KMAIL
296
QIMKE
301
LNKRG
306
RVLVN
311
DAQKV
316
TEGQQ
321
ERLER
326
QHWTM
331
TKIQK
336
HQEHI
341
LRFAS
346
WALES
351
DNNTA
356
LLLSK
361
KLIYF
366
QLHRA
371
LKMIV
376
DPVEP
381
HGEMK
386
FQWDL
391
NAWTK
396
SAEAF
401
GKIVA
406
ERPGT
411
NSTGP
416
APMAP
421
PRAPG
426
PLSKQ
431
GSGSS
436
QPMEV
441
QEGYG
446
FGSGD
451
DPYSS
456
AEPHV
461
SGVKR
466
SRSGE
471
GEVSG
476
LMRKV
481
PRVSL
486
ERLDL
491
DLTAD
496
SQPPV
501
FKVFP
506
GSTTE
511
DYNLI
516
VIERG
521
AAAAA
526
TGQPG
531
TAPAG
536
TPGAP
541
PLAGM
546
AIVKE
551
EETEA
556
AIGAP
561
PTATE
566
GPETK
571
PVLMA
576
LAEGP
581
GAEGP
586
RLASP
591
SGSTS
596
SGLEV
601
VAPEG
606
TSAPG
611
GGPGT
616
LDDSA
621
TICRV
626
CQKPG
631
DLVMC
636
NQCEF
641
CFHLD
646
CHLPA
651
LQDVP
656
GEEWS
661
CSLCH
666
VLPDL
671
KEEDG
676
SLSLD
681
GADST
686
GVVAK
691
LSPAN
696
QRKCE
701
RVLLA
706
LFCHE
711
PCRPL
716
HQLAT
721
DSTFS
726
LDQPG
731
GTLDL
736
TLIRA
741
RLQEK
746
LSPPY
751
SSPQE
756
FAQDV
761
GRMFK
766
QFNKL
771
TEDKA
776
DVQSI
781
IGLQR
786
FFETR
791
MNEAF
796
GDTKF
801
SAVLV
806
EPPPM
811
SLPGA
816
GLSSQ
821
ELSGG
826
PGDGP
831
Mutation Information
DNA mutation:
None
Peptide Range:
370 ~ 394
Mut AA position:
382 (13 in Wild Type peptide)
Alignment
Wild Type:
"FQLHRALKMIVDPVEPHGEMKFQWD
||||||||||||.||||||||||||
Mutant:
FQLHRALKMIVDSVEPHGEMKFQWD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TRIM28

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay