Immunogenicity 6538

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FGD1
Transcript ID
NM_004463
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (961 aa)
MHGHR
1
APGGA
6
GPSEP
11
EHPAT
16
NPPGA
21
APPAC
26
ADSDP
31
GASEP
36
GLLAR
41
RGSGS
46
ALGGP
51
LDPQF
56
VGPSD
61
TSLGA
66
APGHR
71
VLPCG
76
PSPQH
81
HRALR
86
FSYHL
91
EGSQP
96
RPGLH
101
QGNRI
106
LVKSL
111
SLDPG
116
QSLEP
121
HPEGP
126
QRLRS
131
DPGPP
136
TETPS
141
QRPSP
146
LKRAP
151
GPKPQ
156
VPPKP
161
SYLQM
166
PRMPP
171
PLEPI
176
PPPPS
181
RPLPA
186
DPRVA
191
KGLAP
196
RAEAS
201
PSSAA
206
VSSLI
211
EKFER
216
EPVIV
221
ASDRP
226
VPGPS
231
PGPPE
236
PVMLP
241
QPTSQ
246
PPVPQ
251
LPEGE
256
ASRCL
261
FLLAP
266
GPRDG
271
EKVPN
276
RDSGI
281
DSISS
286
PSNSE
291
ETCFV
296
SDDGP
301
PSHSL
306
CPGPP
311
ALASV
316
PVALA
321
DPHRP
326
GSQEV
331
DSDLE
336
EEDDE
341
EEEEE
346
KDREI
351
PVPLM
356
ERQES
361
VELTV
366
QQKVF
371
HIANE
376
LLQTE
381
KAYVS
386
RLHLL
391
DQVFC
396
ARLLE
401
EARNR
406
SSFPA
411
DVVHG
416
IFSNI
421
CSIYC
426
FHQQF
431
LLPEL
436
EKRME
441
EWDRY
446
PRIGD
451
ILQKL
456
APFLK
461
MYGEY
466
VKNFD
471
RAVEL
476
VNTWT
481
ERSTQ
486
FKVII
491
HEVQK
496
EEACG
501
NLTLQ
506
HHMLE
511
PVQRI
516
PRYEL
521
LLKDY
526
LLKLP
531
HGSPD
536
SKDAQ
541
KSLEL
546
IATAA
551
EHSNA
556
AIRKM
561
ERMHK
566
LLKVY
571
ELLGG
576
EEDIV
581
SPTKE
586
LIKEG
591
HILKL
596
SAKNG
601
TTQDR
606
YLILF
611
NDRLL
616
YCVPR
621
LRLLG
626
QKFSV
631
RARID
636
VDGME
641
LKESS
646
NLNLP
651
RTFLV
656
SGKQR
661
SLELQ
666
ARTEE
671
EKKDW
676
VQAIN
681
STLLK
686
HEQTL
691
ETFKL
696
LNSTN
701
REDED
706
TPPNS
711
PNVDL
716
GKRAP
721
TPIRE
726
KEVTM
731
CMRCQ
736
EPFNS
741
ITKRR
746
HHCKA
751
CGHVV
756
CGKCS
761
EFRAR
766
LVYDN
771
NRSNR
776
VCTDC
781
YVALH
786
GVPGS
791
SPACS
796
QHTPQ
801
RRRSI
806
LEKQA
811
SVAAE
816
NSVIC
821
SFLHY
826
MEKGG
831
KGWHK
836
AWFVV
841
PENEP
846
LVLYI
851
YGAPQ
856
DVKAQ
861
RSLPL
866
IGFEV
871
GPPEA
876
GERPD
881
RRHVF
886
KITQS
891
HLSWY
896
FSPET
901
EELQR
906
RWMAV
911
LGRAG
916
RGDTF
921
CPGPT
926
LSEDR
931
EMEEA
936
PVAAL
941
GATAE
946
PPESP
951
QTRDK
956
T
961
Mutation Information
DNA mutation:
None
Peptide Range:
160 ~ 184
Mut AA position:
172 (13 in Wild Type peptide)
Alignment
Wild Type:
"QVPPKPSYLQMPRMPPPLEPIPPPP
||||||||||||.||||||||||||
Mutant:
QVPPKPSYLQMPQMPPPLEPIPPPP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FGD1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay