Immunogenicity 6544

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
RASGRP4
Transcript ID
NM_001146203
HLA INFO
DQA*05:01 / DQB*04:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*04:02
sequence
Full length protein sequence (581 aa)
MNRKD
1
SKRKS
6
HQECT
11
GKIGG
16
RGRPR
21
QVRRH
26
KTCPS
31
PREIS
36
KVMAS
41
MNLGL
46
LSEGG
51
CSEDE
56
LLEKC
61
IQSFD
66
SAGSL
71
CHEDH
76
MLNMV
81
LAMHS
86
WVLPS
91
ADLAA
96
RLLTS
101
YQKAT
106
GDTQE
111
LRRLQ
116
ICHLV
121
RYWLM
126
RHPEV
131
MHQDP
136
QLEEV
141
IGRFW
146
ATVAR
151
EGNSA
156
QRRLG
161
DSSDL
166
LSPGG
171
PGPPL
176
PMSSP
181
GLGKK
186
RKVSL
191
LFDHL
196
ETGEL
201
AQHLT
206
YLEFR
211
SFQAI
216
TPQDL
221
RSYVL
226
QGSVR
231
GCPAL
236
EGSVG
241
LSNSV
246
SRWVQ
251
VMVLS
256
RPGPL
261
QRAQV
266
LDKFI
271
HVAQR
276
LHQLQ
281
NFNTL
286
MAVTG
291
GLCHS
296
AISRL
301
KDSHA
306
HLSPD
311
STKLS
316
LDLFY
321
TEDEI
326
YELSY
331
AREPR
336
CPKSL
341
PPSPF
346
NAPLV
351
VEWAP
356
GVTPK
361
PDRVT
366
LGRHV
371
EQLVE
376
SVFKN
381
YDPEG
386
RGTIS
391
QEDFE
396
RLSGN
401
FPFAC
406
HGLHP
411
PPRQG
416
RGSFS
421
REELT
426
GYLLR
431
ASAIC
436
SKLGL
441
AFLHT
446
FHEVT
451
FRKPT
456
FCDSC
461
SGFLW
466
GVTKQ
471
GYRCR
476
ECGLC
481
CHKHC
486
RDQVK
491
VECKK
496
RPGAK
501
GDAGP
506
PGAPV
511
PSTPA
516
PHASC
521
GSEEN
526
HSYTL
531
SLEPE
536
TGCQL
541
RHAWT
546
QTESP
551
HPSWE
556
TDTVP
561
CPVMD
566
PPSTA
571
SSKLD
576
S
581
Mutation Information
DNA mutation:
None
Peptide Range:
309 ~ 333
Mut AA position:
321 (13 in Wild Type peptide)
Alignment
Wild Type:
"HAHLSPDSTKLSLDLFYTEDEIYEL
||||||||||||.||||||||||||
Mutant:
HAHLSPDSTKLSMDLFYTEDEIYEL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RASGRP4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay