Immunogenicity 656
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NACA
Transcript ID
ENST00000454682
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (2078 aa)
MPGEA
1
TETVP
6
ATEQE
11
LPQPQ
16
AETAV
21
LPMSS
26
ALSVT
31
AALGQ
36
PGPTL
41
PPPCS
46
PAPQQ
51
CPLSA
56
ANQAS
61
PFPSP
66
STIAS
71
TPLEV
76
PFPQS
81
SSGTA
86
LPLGT
91
APEAP
96
TFLPN
101
LIGPP
106
ISPAA
111
LALAS
116
PMIAP
121
TLKGT
126
PSSSA
131
PLALV
136
ALAPH
141
SVQKS
146
SAFPP
151
NLLTS
156
PPSVA
161
VAESG
166
SVITL
171
SAPIA
176
PSEPK
181
TNLNK
186
VPSEV
191
VPNPK
196
GTPSP
201
PCIVS
206
TVPYH
211
CVTPM
216
ASIQS
221
GVASL
226
PQTTP
231
TTTLA
236
IASPQ
241
VKDTT
246
ISSVL
251
ISPQN
256
PGSLS
261
LKGPV
266
SPPAA
271
LSLST
276
QSLPV
281
VTSSQ
286
KTAGP
291
NTPPD
296
FPISL
301
GSHLA
306
PLHQS
311
SFGSV
316
QLLGQ
321
TGPSA
326
LSDPT
331
VKTIS
336
VDHSS
341
TGASY
346
PSQRS
351
VIPPL
356
PSRNE
361
VVPAT
366
VAAFP
371
VVAPS
376
VDKGP
381
STISS
386
ITCSP
391
SGSLN
396
VATSF
401
SLSPT
406
TSLIL
411
KSSPN
416
ATYHY
421
PLVAQ
426
MPVSS
431
VGTTP
436
LVVTN
441
PCTIA
446
AAPTT
451
TFEVA
456
TCVSP
461
PMSSG
466
PISNI
471
EPTSP
476
AALVM
481
APVAP
486
KEPST
491
QVATT
496
LRIPV
501
SPPLP
506
DPEDL
511
KNLPS
516
SVLVK
521
FPTQK
526
DLQTV
531
PASLE
536
GAPFS
541
PAQAG
546
LTTKK
551
DPTVL
556
PLVQA
561
APKNS
566
PSFQS
571
TSSSP
576
EIPLS
581
PEATL
586
AKKSL
591
GEPLP
596
IGKPA
601
SSMTS
606
PLGVN
611
SSASV
616
IKTDS
621
YAGPD
626
SAGPL
631
LKSSL
636
ITPTV
641
AAFPL
646
ESADP
651
AGVAP
656
TTAKG
661
TSTYT
666
TTASP
671
FLEGT
676
VSLAP
681
KNHPV
686
KEGTL
691
TTLPL
696
VPTAS
701
ENCPV
706
APSPQ
711
NTCAP
716
LATLV
721
LAPEI
726
PKSVP
731
SPSLP
736
PAGTP
741
PGTKK
746
VDGIS
751
HTSAL
756
APVAS
761
SPKEC
766
PTEDS
771
GASAT
776
ASSKG
781
TLTYL
786
ADSPS
791
PLGVS
796
VSPQT
801
KRPPT
806
KKGSA
811
GPDTP
816
IGNLS
821
SPVSP
826
VEASF
831
LPENS
836
LSFQG
841
SKDSP
846
ATTHS
851
PTPPS
856
PKGAP
861
TPSAV
866
TPLSP
871
KGVTL
876
PPKET
881
PTPSV
886
VNLPF
891
PKEGP
896
ATPAP
901
KQAPA
906
LSMTS
911
SSPKK
916
ARATP
921
APKGI
926
PASPS
931
PKGAP
936
TPPAA
941
TPPSP
946
KGGPA
951
TPSPK
956
WAPTP
961
PAATP
966
PSPKG
971
GPATP
976
SPKGA
981
PTPPA
986
ATPPS
991
PKGGP
996
ATPSP
1001
KGAPT
1006
PPAVT
1011
PPSPK
1016
GSPAA
1021
TPFPK
1026
GASTP
1031
PAATP
1036
PSPKG
1041
SPAAT
1046
PLPKG
1051
APTTP
1056
AATLP
1061
SPKGG
1066
PATPS
1071
LKGAP
1076
TPPAA
1081
TPPSP
1086
KGGPA
1091
TPSPK
1096
GAPMP
1101
PAATP
1106
PSPKG
1111
GLATP
1116
PHKGA
1121
PTTPA
1126
ATPPS
1131
PKGGL
1136
ATPPP
1141
KGAPT
1146
TPAAT
1151
PPSPK
1156
GGLAT
1161
PPPKG
1166
APTTP
1171
AATPP
1176
SPKGG
1181
LATPS
1186
PKGAP
1191
TTPAA
1196
TPPSP
1201
KGGLA
1206
TPSPK
1211
GAPTT
1216
PAATP
1221
PSPKG
1226
GLATP
1231
SPKGA
1236
PTTPA
1241
ATPPS
1246
PKGGP
1251
ATPPP
1256
KGAPT
1261
PPAAT
1266
PPSLK
1271
GGLAT
1276
PPHKG
1281
APNPA
1286
VVTPP
1291
SPKGG
1296
PATSP
1301
PKGAP
1306
TPPAA
1311
TPPSP
1316
KGSPG
1321
TPPPK
1326
GAPTP
1331
PAVTP
1336
PSPKG
1341
TPTLP
1346
ATTPS
1351
SKGGP
1356
TTPSS
1361
KEGPT
1366
PPAAT
1371
PSHKG
1376
GPAMT
1381
PPSPK
1386
RGPAI
1391
PSPKG
1396
DPTSP
1401
AVIPL
1406
SPKKA
1411
PATPV
1416
TREGA
1421
ATPSK
1426
GDLTP
1431
PAVTP
1436
VSLKK
1441
APATS
1446
APKGG
1451
PATPS
1456
SKGDP
1461
TLPAV
1466
TPPSP
1471
KEPPA
1476
PKQVA
1481
TSSSP
1486
KKAPA
1491
TPAPM
1496
GAPTL
1501
PAVIP
1506
SSPKE
1511
VPATP
1516
SSRRD
1521
PIAPT
1526
ATLLS
1531
KKTPA
1536
TLAPK
1541
EALIP
1546
PAMTV
1551
PSPKK
1556
TPAIP
1561
TPKEA
1566
PATPS
1571
SKEAS
1576
SPPAV
1581
TPSTY
1586
KGAPS
1591
PKELL
1596
IPPAV
1601
TSPSP
1606
KEAPT
1611
PPAVT
1616
PPSPE
1621
KGPAT
1626
PAPKG
1631
TPTSP
1636
PVTPS
1641
SLKDS
1646
PTSPA
1651
SVTCK
1656
MGATV
1661
PQASK
1666
GLPAK
1671
KGPTA
1676
LKEVL
1681
VAPAP
1686
ESTPI
1691
ITAPT
1696
RKGPQ
1701
TKKSS
1706
ATSPP
1711
ICPDP
1716
SAKNG
1721
SKGPL
1726
STVAP
1731
APLLP
1736
VQKDS
1741
SKTAK
1746
GKDAS
1751
HSPKG
1756
PLAPP
1761
ESKAS
1766
TPLTA
1771
AAFEK
1776
VLPKP
1781
ESASV
1786
SAAPS
1791
PPVSL
1796
PLAPS
1801
PVPTL
1806
PPKQQ
1811
FLPSS
1816
PGLVL
1821
ESPSK
1826
PLAPA
1831
DEDEL
1836
LPLIP
1841
PEPIS
1846
GGVPF
1851
QSVLV
1856
NMPTP
1861
KSAGI
1866
PVPTP
1871
SAKQP
1876
VTKNN
1881
KGSGT
1886
ESDSD
1891
ESVPE
1896
LEEQD
1901
STQAT
1906
TQQAQ
1911
LAAAA
1916
EIDEE
1921
PVSKA
1926
KQSRS
1931
EKKAR
1936
KAMSK
1941
LGLRQ
1946
VTGVT
1951
RVTIR
1956
KSKNI
1961
LFVIT
1966
KPDVY
1971
KSPAS
1976
DTYIV
1981
FGEAK
1986
IEDLS
1991
QQAQL
1996
AAAEK
2001
FKVQG
2006
EAVSN
2011
IQENT
2016
QTPTV
2021
QEESE
2026
EEEVD
2031
ETGVE
2036
VKDIE
2041
LVMSQ
2046
ANVSR
2051
AKAVR
2056
ALKNN
2061
SNDIV
2066
NAIME
2071
LTM
2076
Mutation Information
DNA mutation:
None
Peptide Range:
1365 ~ 1389
Mut AA position:
1377 (13 in Wild Type peptide)
Alignment
Wild Type:
"SKEGPTPPAATPSHKGGPAMTPPSP
||||||||||||.||||||||||||
Mutant:
SKEGPTPPAATPPHKGGPAMTPPSP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ENSG00000196531
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay