Immunogenicity 6580

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MGAT5B
Transcript ID
NM_144677
HLA INFO
DQA*02:01 / DQB*02:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:01
sequence
Full length protein sequence (790 aa)
MITVN
1
PDGKI
6
MVRRC
11
LVTLR
16
PFRLF
21
VLGIG
26
FFTLC
31
FLMTS
36
LGGQF
41
SARRL
46
GDSPF
51
TIRTE
56
VMGGP
61
ESRGV
66
LRKMS
71
DLLEL
76
MVKRM
81
DALAR
86
LENSS
91
ELHRA
96
GGDLH
101
FPADR
106
MPPGA
111
GLMER
116
IQAIA
121
QNVSD
126
IAVKV
131
DQILR
136
HSLLL
141
HSKVS
146
EGRRD
151
QCEAP
156
SDPKF
161
PDCSG
166
KVEWM
171
RARWT
176
SDPCY
181
AFFGV
186
DGTEC
191
SFLIY
196
LSEVE
201
WFCPP
206
LPWRN
211
QTAAQ
216
RAPKP
221
LPKVQ
226
AVFRS
231
NLSHL
236
LDLMG
241
SGKES
246
LIFMK
251
KRTKR
256
LTAQW
261
ALAAQ
266
RLAQK
271
LGATQ
276
RDQKQ
281
ILVHI
286
GFLTE
291
ESGDV
296
FSPRV
301
LKGGP
306
LGEMV
311
QWADI
316
LTALY
321
VLGHG
326
LRVTV
331
SLKEL
336
QSNLG
341
VPPGR
346
GSCPL
351
TMPLP
356
FDLIY
361
TDYHG
366
LQQMK
371
RHMGL
376
SFKKY
381
RCRIR
386
VIDTF
391
GTEPA
396
YNHEE
401
YATLH
406
GYRTN
411
WGYWN
416
LNPKQ
421
FMTMF
426
PHTPD
431
NSFMG
436
FVSEE
441
LNETE
446
KRLIK
451
GGKAS
456
NMAVV
461
YGKEA
466
SIWKG
471
KEKFL
476
GILNK
481
YMEIH
486
GTVYY
491
ESQRP
496
PEVPA
501
FVKNH
506
GLLPQ
511
PEFQQ
516
LLRKA
521
KLFIG
526
FGFPY
531
EGPAP
536
LEAIA
541
NGCIF
546
LQSRF
551
SPPHS
556
SLNHE
561
FFRGK
566
PTSRE
571
VFSQH
576
PYAEN
581
FIGKP
586
HVWTV
591
DYNNS
596
EEFEA
601
AIKAI
606
MRTQV
611
DPYLP
616
YEYTC
621
EGMLE
626
RIHAY
631
IQHQD
636
FCRAP
641
DPALP
646
EAHAP
651
QSPFV
656
LAPNA
661
THLEW
666
ARNTS
671
LAPGA
676
WPPAH
681
ALRAW
686
LAVPG
691
RACTD
696
TCLDH
701
GLICE
706
PSFFP
711
FLNSQ
716
DAFLK
721
LQVPC
726
DSTES
731
EMNHL
736
YPAFA
741
QPGQE
746
CYLQK
751
EPLLF
756
SCAGS
761
NTKYR
766
RLCPC
771
RDFRK
776
GQVAL
781
CQGCL
786
Mutation Information
DNA mutation:
None
Peptide Range:
259 ~ 283
Mut AA position:
271 (13 in Wild Type peptide)
Alignment
Wild Type:
"KRLTAQWALAAQRLAQKLGATQRDQ
||||||||||||.||||||||||||
Mutant:
KRLTAQWALAAQHLAQKLGATQRDQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MGAT5B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay