Immunogenicity 6593

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SYTL5
Transcript ID
NM_001163335
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (730 aa)
MSKNS
1
EFINL
6
SFLLD
11
HEKEM
16
ILGVL
21
KRDEY
26
LKKVE
31
DKRIR
36
KLKNE
41
LLEAK
46
RRSGK
51
TQQEA
56
SRVCV
61
HCHRN
66
LGLIF
71
DRGDP
76
CQACS
81
LRVCR
86
ECRVA
91
GPNGS
96
WKCTV
101
CDKIA
106
QLRII
111
TGEWF
116
FEEKA
121
KRFKQ
126
VNVLG
131
TDVVR
136
QSILR
141
RSPGA
146
EEVQS
151
QEQTR
156
QDAEK
161
SDTSP
166
VAGKK
171
ASHDG
176
PKRKG
181
FLLSK
186
FRSAT
191
RGEII
196
TPKTD
201
TGRSY
206
SLDLD
211
GQHFR
216
SLKSP
221
PGSDR
226
GSTGS
231
SDLND
236
QEPGP
241
RTPKS
246
SRSNG
251
VTPGT
256
QSSPA
261
PSTRT
266
VTSVI
271
SREYG
276
FENSM
281
DLAAI
286
EGTSQ
291
ELTKS
296
HRRNT
301
SGTPS
306
IAVSG
311
TSLSS
316
DQSRS
321
ELDLS
326
ESFTE
331
DSEDT
336
VSIRS
341
KSVPG
346
ALDKD
351
SLEET
356
EESID
361
ALVSS
366
QLSTN
371
THRLA
376
SGLST
381
TSLNS
386
MMSVY
391
SETGD
396
YGNVK
401
VSGEI
406
LLHIS
411
YCYKT
416
GGLYI
421
FVKNC
426
RNLAI
431
GDEKK
436
QRTDA
441
YVKSY
446
LLPDK
451
SRNNK
456
RKTKI
461
RTGTN
466
PEFNE
471
TLKYT
476
ISHTQ
481
LETRT
486
LQLSV
491
WHYDR
496
FGRNS
501
FLGEV
506
EIPFD
511
SWNFE
516
NPTDE
521
WFVLQ
526
PKVEF
531
APDIG
536
LQYKG
541
ELTVV
546
LRYIP
551
PEENL
556
MLPPE
561
QLQGN
566
KTFKK
571
GKKKE
576
SPVIS
581
GGILE
586
VFIKE
591
AKNLT
596
AVKSG
601
GTSDS
606
FVKGY
611
LLPDD
616
SKATK
621
HKTLV
626
IKKSV
631
NPQWN
636
HTFMF
641
SGIHP
646
QDIKN
651
VCLEL
656
TIWDK
661
EAFSS
666
NIFLG
671
GVRLN
676
SGSGV
681
SHGKN
686
VDWMD
691
SQGEE
696
QRLWQ
701
KMANN
706
PGTPF
711
EGVLM
716
LRSSM
721
GKCRL
726
Mutation Information
DNA mutation:
None
Peptide Range:
236 ~ 260
Mut AA position:
248 (13 in Wild Type peptide)
Alignment
Wild Type:
"SDLNDQEPGPRTPKSSRSNGVTPGT
||||||||||||.||||||||||||
Mutant:
SDLNDQEPGPRTLKSSRSNGVTPGT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SYTL5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay