Immunogenicity 6598
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TFAP2E
Transcript ID
NM_178548
HLA INFO
C*05:01
TCR INFO
No TCR info found!
Full length protein sequence (442 aa)
MLVHT
1
YSAME
6
RPDGL
11
GAAAG
16
GARLS
21
SLPQA
26
AYGPA
31
PPLCH
36
TPAAT
41
AAAEF
46
QPPYF
51
PPPYP
56
QPPLP
61
YGQAP
66
DAAAA
71
FPHLA
76
GDPYG
81
GLAPL
86
AQPQP
91
PQAAW
96
AAPRA
101
AARAH
106
EEPPG
111
LLAPP
116
ARALG
121
LDPRR
126
DYATA
131
VPRLL
136
HGLAD
141
GAHGL
146
ADAPL
151
GLPGL
156
AAAPG
161
LEDLQ
166
AMDEP
171
GMSLL
176
DQSVI
181
KKVPI
186
PSKAS
191
SLSAL
196
SLAKD
201
SLVGG
206
ITNPG
211
EVFCS
216
VPGRL
221
SLLSS
226
TSKYK
231
VTVGE
236
VQRRL
241
SPPEC
246
LNASL
251
LGGVL
256
RRAKS
261
KNGGR
266
CLRER
271
LEKIG
276
LNLPA
281
GRRKA
286
ANVTL
291
LTSLV
296
EGEAV
301
HLARD
306
FGYVC
311
ETEFP
316
AKAAA
321
EYLCR
326
QHADP
331
GELHS
336
RKSML
341
LAAKQ
346
ICKEF
351
ADLMA
356
QDRSP
361
LGNSR
366
PALIL
371
EPGVQ
376
SCLTH
381
FSLIT
386
HGFGG
391
PAICA
396
ALTAF
401
QNYLL
406
ESLKG
411
LDKMF
416
LSSVG
421
SGHGE
426
TKASE
431
KDAKH
436
RK
441
Mutation Information
DNA mutation:
None
Peptide Range:
382 ~ 406
Mut AA position:
394 (13 in Wild Type peptide)
Alignment
Wild Type:
"CLTHFSLITHGFGGPAICAALTAFQ
||||||||||||.||||||||||||
Mutant:
CLTHFSLITHGFAGPAICAALTAFQ"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TFAP2E
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay