Immunogenicity 6615

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TIMM21
Transcript ID
NM_014177
HLA INFO
DRB*03:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*03:01
sequence
Full length protein sequence (248 aa)
MICTF
1
LRAVQ
6
YTEKL
11
HRSSA
16
KRLLL
21
PYIVL
26
NKACL
31
KTEPS
36
LRCGL
41
QYQKK
46
TLRPR
51
CILGV
56
TQKTI
61
WTQGP
66
SPRKA
71
KEDGS
76
KQVSV
81
HRSQR
86
GGTAV
91
PTSQK
96
VKEAG
101
RDFTY
106
LIVVL
111
FGISI
116
TGGLF
121
YTIFK
126
ELFSS
131
SSPSK
136
IYGRA
141
LEKCR
146
SHPEV
151
IGVFG
156
ESVKG
161
YGEVT
166
RRGRR
171
QHVRF
176
TEYVK
181
DGLKH
186
TCVKF
191
YIEGS
196
EPGKQ
201
GTVYA
206
QVKEN
211
PGSGE
216
YDFRY
221
IFVEI
226
ESYPR
231
RTIII
236
EDNRS
241
QDD
246
Mutation Information
DNA mutation:
None
Peptide Range:
115 ~ 139
Mut AA position:
127 (13 in Wild Type peptide)
Alignment
Wild Type:
"LFGISITGGLFYTIFKELFSSSSPS
||||||||||||.||||||||||||
Mutant:
LFGISITGGLFYMIFKELFSSSSPS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TIMM21

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay