Immunogenicity 664

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
POTEG
Transcript ID
ENST00000409832
HLA INFO
DRB*03:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*03:01
sequence
Full length protein sequence (508 aa)
MVAEA
1
GSMPA
6
ASSVK
11
KPFGL
16
RSKMG
21
KWCRH
26
CFPWC
31
RGSGK
36
SNVGT
41
SGDHD
46
DSAMK
51
TLRSK
56
MGKWC
61
RHCFP
66
WCRGS
71
SKSNV
76
GTSGD
81
HDDSA
86
MKTLR
91
SKMGK
96
WCCHC
101
FPCCR
106
GSGKS
111
KVGPW
116
GDYDD
121
SAFME
126
PRYHV
131
RREDL
136
DKLHR
141
AAWWG
146
KVPRK
151
DLIVM
156
LKDTD
161
MNKKD
166
KQKRT
171
ALHLA
176
SANGN
181
SEVVK
186
LLLDR
191
RCQLN
196
ILDNK
201
KRTAL
206
TKAVQ
211
CREDE
216
CALML
221
LEHGT
226
DPNIP
231
DEYGN
236
TALHY
241
AIYNE
246
DKLMA
251
KALLL
256
YGADI
261
ESKNK
266
HGLTP
271
LLLGV
276
HEQKQ
281
QVVKF
286
LIKKK
291
ANLNA
296
LDRYG
301
RTALI
306
LAVCC
311
GSASI
316
VSLLL
321
EQNID
326
VSSQD
331
LSGQT
336
AREYA
341
VSSHH
346
NVICQ
351
LLSDY
356
KEKQM
361
LKVSS
366
ENSNP
371
EQDLK
376
LTSEE
381
ESQRL
386
KGSEN
391
SQPEE
396
MSQEP
401
EINKG
406
GDRKV
411
EEEMK
416
KHGST
421
HMGFP
426
ENLPN
431
GATAD
436
NGDDG
441
LIPPR
446
KSRTP
451
ESQQF
456
PDTEN
461
EQYHS
466
DEQND
471
TQKQL
476
SEEQN
481
TGILQ
486
DEILI
491
HEEKQ
496
IEVAE
501
NEF
506
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 19
Mut AA position:
7 (7 in Wild Type peptide)
Alignment
Wild Type:
"MVAEAGSMPAASSVKKPFGLRSKMG
||||||.||||||||||||
Mutant:
MVAEAGLMPAASSVKKPFG------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) POTEG

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay