Immunogenicity 6705

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TMEM245
Transcript ID
NM_032012
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (879 aa)
MADGG
1
GPKDA
6
PSLRS
11
SPGPA
16
PRVPR
21
AVGPS
26
GGGGE
31
TPRTA
36
ALALR
41
FDKPI
46
KQAFY
51
NTGAV
56
LFVCL
61
CCGAA
66
VLVYF
71
ILEAF
76
LRPLL
81
WAVLC
86
GTFLH
91
PFKSS
96
LTRLG
101
RHWLQ
106
RLHRA
111
HTPIV
116
LAALL
121
LPLCF
126
VDYGV
131
EALGE
136
QALRR
141
RRLLL
146
LLGAG
151
GPLLY
156
GLYCL
161
GSYLG
166
VQVLL
171
VHAAT
176
LICRG
181
LDYFS
186
SLWIW
191
TLVVG
196
YVLTV
201
SFKWN
206
ASTER
211
YLRAV
216
SIPVW
221
IILLF
226
HLASL
231
AGSWR
236
IPVFL
241
VIVFL
246
MSVGT
251
LYEKQ
256
NGKES
261
SGAEL
266
PGQVI
271
SMAAS
276
TLANL
281
AISIT
286
GYESS
291
SEDQP
296
STQPA
301
EAVDR
306
GESAP
311
TLSTS
316
PSPSS
321
PSPTS
326
PSPTL
331
GRRRP
336
EIGTF
341
LRKKK
346
TSDIY
351
FVSLV
356
WAIVV
361
MQIWL
366
NLWIV
371
QLLPV
376
PIAVW
381
ILKKL
386
VIHFG
391
VVDFL
396
EKRYH
401
VWWGI
406
IESFL
411
KERQG
416
ALAPW
421
PIVGL
426
GKFLL
431
KVDSK
436
LWHWL
441
NKKMI
446
IWLEK
451
MLDKI
456
ISIFI
461
IFLLV
466
IGTLL
471
LALLL
476
TAKVH
481
QESVH
486
MIEVT
491
SNLIN
496
ETLAN
501
HPEWA
506
NWLPE
511
AQVVQ
516
RALNS
521
AANNV
526
YQYGR
531
EWITH
536
KLHKI
541
LGDKV
546
NNTAV
551
IEKQV
556
LELWD
561
RLYHS
566
WFVKN
571
VTHSG
576
RHKGQ
581
KLHVS
586
RQNSW
591
LGDIL
596
DWQDI
601
VSFVH
606
ENIET
611
FLSIL
616
ESLWI
621
VMSRN
626
VSLLF
631
TTVTT
636
LLTIL
641
FYSGT
646
ALLNF
651
VLSLI
656
IFLTT
661
LFYLL
666
SSSDE
671
YYKPV
676
KWVIS
681
LTPLS
686
QPGPS
691
SNIIG
696
QSVEE
701
AIRGV
706
FDASL
711
KMAGF
716
YGLYT
721
WLTHT
726
MFGIN
731
IVFIP
736
SALAA
741
ILGAV
746
PFLGT
751
YWAAV
756
PAVLD
761
LWLTQ
766
GLGCK
771
AILLL
776
IFHLL
781
PTYFV
786
DTAIY
791
SDISG
796
GGHPY
801
LTGLA
806
VAGGA
811
YYLGL
816
EGAII
821
GPILL
826
CILVV
831
ASNIY
836
SAMLV
841
SPTNS
846
VPTPN
851
QTPWP
856
AQPQR
861
TFRDI
866
SEDLK
871
SSVG
876
Mutation Information
DNA mutation:
None
Peptide Range:
23 ~ 47
Mut AA position:
35 (13 in Wild Type peptide)
Alignment
Wild Type:
"VPRAVGPSGGGGETPRTAALALRFD
||||||||||||.||||||||||||
Mutant:
VPRAVGPSGGGGGTPRTAALALRFD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TMEM245

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay