Immunogenicity 6742

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SYT14
Transcript ID
NM_001146264
HLA INFO
DQA*02:01 / DQB*02:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:01
sequence
Full length protein sequence (600 aa)
MASAS
1
WRLKV
6
EREPV
11
EYMNL
16
SVLEK
21
IGYFS
26
VARLE
31
YSGTI
36
LAHCN
41
FRLLG
46
SNDSS
51
ASASQ
56
VTGTT
61
VSPEA
66
VGFLS
71
AVGVF
76
IILML
81
LLFLY
86
INKKF
91
CFENV
96
GGFPD
101
LGSEY
106
STRKN
111
SQDKI
116
YNSYM
121
DKDEH
126
GSSSE
131
SEDEA
136
LGKYH
141
EALSR
146
THNSR
151
LPLAD
156
SRQRN
161
YAWET
166
RQKYS
171
PLSAE
176
YDGYS
181
SEASI
186
DEGNC
191
IQRMR
196
RTPPL
201
DELQP
206
PPYQD
211
DSGSP
216
HLSCT
221
PSEIG
226
DSKCE
231
FSHCS
236
NSPRC
241
SYNKC
246
PSEGS
251
TGHEI
256
ESFHN
261
KGYEE
266
DVPSD
271
STAVL
276
SPEDM
281
SAQGS
286
SSQLP
291
KPFDP
296
EPEAK
301
YGTLD
306
VTFDY
311
DSQEQ
316
KLLVT
321
VTAVT
326
DIPTY
331
NRTGG
336
NSWQV
341
HLVLL
346
PIKKQ
351
RAKTS
356
IQRGP
361
CPVFT
366
ETFKF
371
NHVES
376
EMIGN
381
YAVRF
386
RLYGV
391
HRMKK
396
EKIVG
401
EKIFY
406
LTKLN
411
LQGKM
416
SLPVI
421
LEPSY
426
NHSGC
431
DSQMS
436
VSEMS
441
CSEST
446
SSCQS
451
LEHGS
456
VPEIL
461
IGLLY
466
NATTG
471
RLSAE
476
VIKGS
481
HFKNL
486
AANRP
491
PNTYV
496
KLTLL
501
NSMGQ
506
EMSKC
511
KTSIR
516
RGQPN
521
PVYKE
526
TFVFQ
531
VALFQ
536
LSDVT
541
LILSV
546
YNKRS
551
MKRKE
556
MIGWI
561
SLGLN
566
SSGEE
571
ELNHW
576
TEMKE
581
SKGQQ
586
VCRWH
591
ALLES
596
Mutation Information
DNA mutation:
None
Peptide Range:
70 ~ 94
Mut AA position:
82 (13 in Wild Type peptide)
Alignment
Wild Type:
"AVGFLSAVGVFIILMLLLFLYINKK
||||||||||||.||||||||||||
Mutant:
AVGFLSAVGVFIMLMLLLFLYINKK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SYT14

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay