Immunogenicity 6759

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GRM4
Transcript ID
NM_001256813
HLA INFO
B*13:02
TCR INFO

No TCR info found!

T cell Tumor cell B*13:02
sequence
Full length protein sequence (779 aa)
MAVPL
1
GAPCW
6
ASALP
11
AWAPP
16
GLPHR
21
SLLTR
26
LLSQH
31
VKPAK
36
IPQIS
41
YASTA
46
PDLSD
51
NSRYD
56
FFSRV
61
VPSDT
66
YQAQA
71
MVDIV
76
RALKW
81
NYVST
86
VASEG
91
SYGES
96
GVEAF
101
IQKSR
106
EDGGV
111
CIAQS
116
VKIPR
121
EPKAG
126
EFDKI
131
IRRLL
136
ETSNA
141
RAVII
146
FANED
151
DIRRV
156
LEAAR
161
RANQT
166
GHFFW
171
MGSDS
176
WGSKI
181
APVLH
186
LEEVA
191
EGAVT
196
ILPKR
201
MSVRG
206
FDRYF
211
SSRTL
216
DNNRR
221
NIWFA
226
EFWED
231
NFHCK
236
LSRHA
241
LKKGS
246
HVKKC
251
TNRER
256
IGQDS
261
AYEQE
266
GKVQF
271
VIDAV
276
YAMGH
281
ALHAM
286
HRDLC
291
PGRVG
296
LCPRM
301
DPVDG
306
TQLLK
311
YIRNV
316
NFSGI
321
AGNPV
326
TFNEN
331
GDAPG
336
RYDIY
341
QYQLR
346
NDSAE
351
YKVIG
356
SWTDH
361
LHLRI
366
ERMHW
371
PGSGQ
376
QLPRS
381
ICSLP
386
CQPGE
391
RKKTV
396
KGMPC
401
CWHCE
406
PCTGY
411
QYQVD
416
RYTCK
421
TCPYD
426
MRPTE
431
NRTGC
436
RPIPI
441
IKLEW
446
GSPWA
451
VLPLF
456
LAVVG
461
IAATL
466
FVVIT
471
FVRYN
476
DTPIV
481
KASGR
486
ELSYV
491
LLAGI
496
FLCYA
501
TTFLM
506
IAEPD
511
LGTCS
516
LRRIF
521
LGLGM
526
SISYA
531
ALLTK
536
TNRIY
541
RIFEQ
546
GKRSV
551
SAPRF
556
ISPAS
561
QLAIT
566
FSLIS
571
LQLLG
576
ICVWF
581
VVDPS
586
HSVVD
591
FQDQR
596
TLDPR
601
FARGV
606
LKCDI
611
SDLSL
616
ICLLG
621
YSMLL
626
MVTCT
631
VYAIK
636
TRGVP
641
ETFNE
646
AKPIG
651
FTMYT
656
TCIVW
661
LAFIP
666
IFFGT
671
SQSAD
676
KLYIQ
681
TTTLT
686
VSVSL
691
SASVS
696
LGMLY
701
MPKVY
706
IILFH
711
PEQNV
716
PKRKR
721
SLKAV
726
VTAAT
731
MSNKF
736
TQKGN
741
FRPNG
746
EAKSE
751
LCENL
756
EAPAL
761
ATKQT
766
YVTYT
771
NHAI
776
Mutation Information
DNA mutation:
None
Peptide Range:
147 ~ 171
Mut AA position:
159 (13 in Wild Type peptide)
Alignment
Wild Type:
"AVIIFANEDDIRRVLEAARRANQTG
||||||||||||.||||||||||||
Mutant:
AVIIFANEDDIRHVLEAARRANQTG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRM4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay