Immunogenicity 6795

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TPCN1
Transcript ID
NM_001143819
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (888 aa)
MESCY
1
IAQAG
6
LELLG
11
SSSSP
16
TLTSQ
21
SAEIT
26
EDASN
31
GGVSE
36
QHPWP
41
SGFER
46
ELKPE
51
TISSP
56
GYHIL
61
RATGE
66
ENMAV
71
SLDDD
76
VPLIL
81
TLDEG
86
GSAPL
91
APSNG
96
LGQEE
101
LPSKN
106
GGSYA
111
IHDSQ
116
APSLS
121
SGGES
126
SPSSP
131
AHNWE
136
MNYQE
141
AAIYL
146
QEGEN
151
NDKFF
156
THPKD
161
AKALA
166
AYLFA
171
HNHLF
176
YLMEL
181
ATALL
186
LLLLS
191
LCEAP
196
AVPAL
201
RLGIY
206
VHATL
211
ELFAL
216
MVVVF
221
ELCMK
226
LRWLG
231
LHTFI
236
RHKRT
241
MVKTS
246
VLVVQ
251
FVEAI
256
VVLVR
261
QMSHV
266
RVTRA
271
LRCIF
276
LVDCR
281
YCGGV
286
RRNLR
291
QIFQS
296
LPPFM
301
DILLL
306
LLFFM
311
IIFAI
316
LGFYL
321
FSPNP
326
SDPYF
331
STLEN
336
SIVSL
341
FVLLT
346
TANFP
351
DVMMP
356
SYSRN
361
PWSCV
366
FFIVY
371
LSIEL
376
YFIMN
381
LLLAV
386
VFDTF
391
NDIEK
396
RKFKS
401
LLLHK
406
RTAIQ
411
HAYRL
416
LISQR
421
RPAGI
426
SYRQF
431
EGLMR
436
FYKPR
441
MSARE
446
RYLTF
451
KALNQ
456
NNTPL
461
LSLKD
466
FYDIY
471
EVAAL
476
KWKAK
481
KNREH
486
WFDEL
491
PRTAL
496
LIFKG
501
INILV
506
KSKAF
511
QYFMY
516
LVVAV
521
NGVWI
526
LVETF
531
MLKGG
536
NFFSK
541
HVPWS
546
YLVFL
551
TIYGV
556
ELFLK
561
VAGLG
566
PVEYL
571
SSGWN
576
LFDFS
581
VTVFA
586
FLGLL
591
ALALN
596
MEPFY
601
FIVVL
606
RPLQL
611
LRLFK
616
LKERY
621
RNVLD
626
TMFEL
631
LPRMA
636
SLGLT
641
LLIFY
646
YSFAI
651
VGMEF
656
FCGIV
661
FPNCC
666
NTSTV
671
ADAYR
676
WRNHT
681
VGNRT
686
VVEEG
691
YYYLN
696
NFDNI
701
LNSFV
706
TLFEL
711
TVVNN
716
WYIIM
721
EGVTS
726
QTSHW
731
SRLYF
736
MTFYI
741
VTMVV
746
MTIIV
751
AFILE
756
AFVFR
761
MNYSR
766
KNQDS
771
EVDGG
776
ITLEK
781
EISKE
786
ELVAV
791
LELYR
796
EARGA
801
SSDVT
806
RLLET
811
LSQME
816
RYQQH
821
SMVFL
826
GRRSR
831
TKSDL
836
SLKMY
841
QEEIQ
846
EWYEE
851
HAREQ
856
EQQRQ
861
LSSSA
866
APAAQ
871
QPPGS
876
RQRSQ
881
TVT
886
Mutation Information
DNA mutation:
None
Peptide Range:
439 ~ 463
Mut AA position:
451 (13 in Wild Type peptide)
Alignment
Wild Type:
"MRFYKPRMSARERYLTFKALNQNNT
||||||||||||.||||||||||||
Mutant:
MRFYKPRMSAREHYLTFKALNQNNT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TPCN1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay