Immunogenicity 68
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
HEATR5B
Transcript ID
uc002rpp.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (2070 aa)
MELAH
1
SLLLN
6
EEALA
11
QITEA
16
KRPVF
21
IFEWL
26
RFLDK
31
VLVAA
36
NKTDV
41
KEKQK
46
KLVEQ
51
LTGLI
56
SSSPG
61
PPTRK
66
LLAKN
71
LAALY
76
SIGDT
81
FTVFQ
86
TLDKC
91
NDIIR
96
NKDDT
101
AAYLP
106
TKLAA
111
VACVG
116
AFYEK
121
MGRML
126
GSAFP
131
ETVNN
136
LLKSL
141
KSAES
146
QGRSE
151
ILMSL
156
QKVLS
161
GLGGA
166
AASSH
171
RDIYK
176
NARSL
181
LTDRS
186
MAVRC
191
AVAKC
196
LLELQ
201
NEAVF
206
MWTAE
211
LENIA
216
TLCFK
221
ALENS
226
NYGVR
231
VAVSK
236
LLGTV
241
MATAL
246
MPKQA
251
TVMRQ
256
NVKRA
261
TFDEV
266
LELMA
271
TGFLR
276
GGSGF
281
LKSGG
286
EMLKV
291
GGSVN
296
REVRV
301
GVTQA
306
YVVFV
311
TTLGG
316
QWLER
321
SFATF
326
LSHVL
331
DLVSH
336
PRATQ
341
THVEA
346
VYSRR
351
CVSFI
356
LRATV
361
GSLLG
366
EKAQI
371
AAAKE
376
ICQAI
381
GKQMK
386
AVEAV
391
VNDTS
396
GENKS
401
GAADI
406
AASQH
411
VMVCA
416
LQELG
421
SLVQS
426
LNATA
431
SPLIQ
436
EASIG
441
LLEIV
446
TSVLL
451
HPSMA
456
ARLAA
461
AWCLR
466
CVAVA
471
LPFQL
476
TPFLD
481
RCAER
486
LNNLK
491
TSPEA
496
VSGYS
501
FAMAA
506
LLGGV
511
HQCPL
516
GIPHA
521
KGKMV
526
VSIAE
531
DLLRT
536
AAQNS
541
RLSLQ
546
RTQAG
551
WLLLG
556
ALMTL
561
GPSVV
566
RYHLP
571
KMLLL
576
WRNVF
581
PRSLK
586
ELEAE
591
KARGD
596
SFTWQ
601
VTLEG
606
RAGAL
611
CAMRS
616
FVAHC
621
PELLT
626
EDVIR
631
KLMTP
636
IECAM
641
TMMSH
646
IPSVM
651
KAHGA
656
HLKAS
661
AAMVR
666
LRLYD
671
ILALL
676
PPKTY
681
EGSFN
686
ALLRE
691
LVAEF
696
TLTDN
701
SANTT
706
TSLLR
711
SLCHY
716
DDSVL
721
LGSWL
726
QETDH
731
KSIED
736
QLQPN
741
SASGS
746
GALEH
751
DPSSI
756
YLRIP
761
AGEAV
766
PGPLP
771
LGVSV
776
IDASV
781
ALFGV
786
VFPHV
791
SYKHR
796
LQMLD
801
HFAEC
806
VKQAK
811
GVRQQ
816
AVQLN
821
IFTAV
826
LSALK
831
GLAEN
836
KSTLG
841
PEEVR
846
KSALT
851
LVMGP
856
LDNPN
861
PILRC
866
AAGEA
871
LGRMA
876
QVVGE
881
ATFIA
886
RMAQY
891
SFDKL
896
KSARD
901
VVSRT
906
GHSLA
911
LGCLH
916
RYVGG
921
IGSGQ
926
HLKTS
931
VSILL
936
ALAQD
941
GTSPE
946
VQTWS
951
LHSLA
956
LIVDS
961
SGPMY
966
RGYVE
971
PTLSL
976
VLTLL
981
LTVPP
986
SHTEV
991
HQCLG
996
RCLGA
1001
IITTV
1006
GPELQ
1011
GNGAT
1016
TSTIR
1021
SSCLV
1026
GCAIT
1031
QDHSD
1036
SLVQA
1041
AAISC
1046
LQQLH
1051
MFAPR
1056
HVNLS
1061
SLVPS
1066
LCVHL
1071
CSSHL
1076
LLRRA
1081
AVACL
1086
RQLAQ
1091
REAAE
1096
VCEYA
1101
MSLAK
1106
NTGDK
1111
ESSSA
1116
NVSPF
1121
APGVS
1126
SRTDI
1131
HCRHQ
1136
GVNIT
1141
ETGLE
1146
GLLFG
1151
MLDRE
1156
TDRKL
1161
CSDIH
1166
DTLGH
1171
MLSSL
1176
AVEKL
1181
SHWLM
1186
LCKDV
1191
LAASS
1196
DMSTA
1201
TLLSS
1206
GKDEE
1211
AEKKD
1216
EMDDD
1221
TMFTT
1226
LGEED
1231
KSKPF
1236
VAPRW
1241
ATRVF
1246
AADCL
1251
CRIIN
1256
LCENA
1261
DQAHF
1266
DLALA
1271
RSAKL
1276
RNPTN
1281
DLLVL
1286
HLSDL
1291
IRMAF
1296
MAATD
1301
HSNQL
1306
RMAGL
1311
QALED
1316
IIKKF
1321
ASVPE
1326
PEFPG
1331
HVILE
1336
QYQAN
1341
VGAAL
1346
RPAFS
1351
QDTPS
1356
DIIAK
1361
ACQVC
1366
STWIG
1371
SGVVS
1376
DLNDL
1381
RRVHN
1386
LLVSS
1391
LDKVQ
1396
AGKGS
1401
SSQLY
1406
RESAT
1411
TMEKL
1416
AVLKA
1421
WAEVY
1426
VVAMN
1431
IKKEA
1436
ESKPK
1441
RAIKN
1446
TDDDD
1451
DDCGT
1456
IDELP
1461
PDSLI
1466
TLVQP
1471
ELPTL
1476
SRLWL
1481
AALKD
1486
YALLT
1491
LPAEF
1496
SSQLP
1501
PDGGA
1506
FYTPE
1511
TIDTA
1516
RLHYR
1521
NSWAP
1526
ILHAV
1531
ALWLN
1536
STGFT
1541
CSEST
1546
EAAAI
1551
SGLQK
1556
RSTSV
1561
NLNQA
1566
SGAVG
1571
SAKSL
1576
PEINK
1581
DRMHL
1586
ILGVS
1591
IQFLC
1596
SPRPE
1601
EPIEH
1606
VTACL
1611
QALHT
1616
LLDSP
1621
YARVH
1626
IAEDQ
1631
LIGVE
1636
LLSVL
1641
HRLLL
1646
TWNPS
1651
SVQLL
1656
VTGVV
1661
QQIVR
1666
AAQDY
1671
LQEKR
1676
NTLNE
1681
DDMEK
1686
EACTV
1691
LGEGG
1696
DSGGL
1701
IPGKS
1706
LVFAT
1711
MELLM
1716
FILVR
1721
HMPHL
1726
STKVS
1731
DSPSH
1736
IATKT
1741
RLSEE
1746
SARLV
1751
AATVT
1756
ILSDL
1761
PSLCS
1766
PAGCM
1771
TILPT
1776
ILFLI
1781
ARILK
1786
DTAIK
1791
SADNQ
1796
VPPPV
1801
SAALQ
1806
GIKSI
1811
VTLSM
1816
AKTEA
1821
GVQKQ
1826
WTALI
1831
RSTLA
1836
CILEY
1841
SQPDS
1846
VPTPD
1851
EVSML
1856
TAIAL
1861
FLWSA
1866
SNEII
1871
GVQSL
1876
QNGCM
1881
NRFKN
1886
ALNSC
1891
DPWVQ
1896
AKCYQ
1901
LLLSV
1906
FQHSN
1911
RALST
1916
PYIHS
1921
LAPIV
1926
VEKLK
1931
AVERN
1936
RPASN
1941
IELLA
1946
VQEGI
1951
KVLET
1956
LVALG
1961
EEQNR
1966
VQLLA
1971
LLVPT
1976
LISYL
1981
LDENS
1986
FASAS
1991
SASKD
1996
LHEFA
2001
LQNLM
2006
HIGPL
2011
YPHAF
2016
KTVMG
2021
AAPEL
2026
KVRLE
2031
TAVRA
2036
SQASK
2041
AKAAA
2046
RQPAP
2051
AIHSA
2056
PTIKL
2061
KTSFF
2066
Mutation Information
DNA mutation:
c.G3757A
Peptide Range:
1241 ~ 1265
Mut AA position:
1253 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAPRWATRVFAADCLCRIINLCENA
||||||||||||.||||||||||||
Mutant:
VAPRWATRVFAANCLCRIINLCENA"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) HEATR5B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VAPRWATRVFAANCLCRIINLCENA
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT