Immunogenicity 681
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FAT4
Transcript ID
ENST00000394329
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO
No TCR info found!
Full length protein sequence (4981 aa)
MDLAP
1
DRATG
6
RPWLP
11
LHTLS
16
VSQLL
21
RVFWL
26
LSLLP
31
GQAWV
36
HGAEP
41
RQVFQ
46
VLEEQ
51
PPGTL
56
VGTIQ
61
TRPGF
66
TYRLS
71
ESHAL
76
FAINS
81
STGAL
86
YTTST
91
IDRES
96
LPSDV
101
INLVV
106
LSSAP
111
TYPTE
116
VRVLV
121
RDLND
126
NAPVF
131
PDPSI
136
VVTFK
141
EDSSS
146
GRQVI
151
LDTAT
156
DSDIG
161
SNGVD
166
HRSYR
171
IIRGN
176
EAGRF
181
RLDIT
186
LNPSG
191
EGAFL
196
HLVSK
201
GGLDR
206
EVTPQ
211
YQLLV
216
EVEDK
221
GEPKR
226
RGYLQ
231
VNVTV
236
QDIND
241
NPPVF
246
GSSHY
251
QAGVP
256
EDAVV
261
GSSVL
266
QVAAA
271
DADEG
276
TNADI
281
RYRLQ
286
DEGTP
291
FQMDP
296
ETGLI
301
TVREP
306
LDFEA
311
RRQYS
316
LTVQA
321
MDRGV
326
PSLTG
331
RAEAL
336
IQLLD
341
VNDND
346
PVVKF
351
RYFPA
356
TSRYA
361
SVDEN
366
AQVGT
371
VVALL
376
TVTDA
381
DSPAA
386
NGNIS
391
VQILG
396
GNEQR
401
HFEVQ
406
SSKVP
411
NLSLI
416
KVASA
421
LDRER
426
IPSYN
431
LTVSV
436
SDNYG
441
APPGA
446
AVQAR
451
SSVAS
456
LVIFV
461
NDIND
466
HPPVF
471
SQQVY
476
RVNLS
481
EEAPP
486
GSYVS
491
GISAT
496
DGDSG
501
LNANL
506
RYSIV
511
SGNGL
516
GWFHI
521
SEHSG
526
LVTTG
531
SSGGL
536
DRELA
541
SQIVL
546
NISAR
551
DQGVH
556
PKVSY
561
AQLVV
566
TLLDV
571
NDEKP
576
VFSQP
581
EGYDV
586
SVVEN
591
APTGT
596
ELLML
601
RATDG
606
DLGDN
611
GTVRF
616
SLQEA
621
ETDRR
626
SFRLD
631
PVSGR
636
LSTIS
641
SLDRE
646
EQAFY
651
SLLVL
656
ATDLG
661
SPPQS
666
SMARI
671
NVSLL
676
DINDN
681
SPVFY
686
PVQYF
691
AHIKE
696
NEPGG
701
SYITT
706
VSATD
711
PDLGT
716
NGTVK
721
YSISA
726
GDRSR
731
FQVNA
736
QSGVI
741
STRMA
746
LDREE
751
KTAYQ
756
LQIVA
761
TDGGN
766
LQSPN
771
QAIVT
776
ITVLD
781
TQDNP
786
PVFSQ
791
VAYSF
796
VVFEN
801
VALGY
806
HVGSV
811
SASTM
816
DLNSN
821
ISYLI
826
TTGDQ
831
KGMFA
836
INQVT
841
GQLTT
846
ANVID
851
REEQS
856
FYQLK
861
VVASG
866
GTVTG
871
DTMVN
876
ITVKD
881
LNDNS
886
PHFLQ
891
AIESV
896
NVVEN
901
WQAGH
906
SIFQA
911
KAVDP
916
DEGVN
921
GMVLY
926
SLKQN
931
PKNLF
936
AINEK
941
NGTIS
946
LLGPL
951
DVHAG
956
SYQIE
961
ILASD
966
MGVPQ
971
LSSSV
976
ILTVY
981
VHDVN
986
DNSPV
991
FDQLS
996
YEVTL
1001
SESEP
1006
VNSRF
1011
FKVQA
1016
SDKDS
1021
GANGE
1026
IAYTI
1031
AEGNT
1036
GDAFG
1041
IFPDG
1046
QLYIK
1051
SELDR
1056
ELQDR
1061
YVLMV
1066
VASDR
1071
AVEPL
1076
SATVN
1081
VTVIL
1086
EDVND
1091
NRPLF
1096
NSTNY
1101
TFYFE
1106
EEQRA
1111
GSFVG
1116
KVSAV
1121
DKDFG
1126
PNGEV
1131
RYSFE
1136
MVQPD
1141
FELHA
1146
ISGEI
1151
TNTHQ
1156
FDRES
1161
LMRRR
1166
GTAVF
1171
SFTVI
1176
ATDQG
1181
IPQPL
1186
KDQAT
1191
VHVYM
1196
KDIND
1201
NAPKF
1206
LKDFY
1211
QATIS
1216
ESAAN
1221
LTQVL
1226
RVSAS
1231
DVDEG
1236
NNGLI
1241
HYSII
1246
KGNEE
1251
RQFAI
1256
DSTSG
1261
QVTLI
1266
GKLDY
1271
EATPA
1276
YSLVI
1281
QAVDS
1286
GTIPL
1291
NSTCT
1296
LNIDI
1301
LDEND
1306
NTPSF
1311
PKSTL
1316
FVDVL
1321
ENMRI
1326
GELVS
1331
SVTAT
1336
DSDSG
1341
DNADL
1346
YYSIT
1351
GTNNH
1356
GTFSI
1361
SPNTG
1366
SIFLA
1371
KKLDF
1376
ETQSL
1381
YKLNI
1386
TAKDQ
1391
GRPPR
1396
SSTMS
1401
VVIHV
1406
RDFND
1411
NPPSF
1416
PPGDI
1421
FKSIV
1426
ENIPI
1431
GTSVI
1436
SVTAH
1441
DPDAD
1446
INGQL
1451
SYTII
1456
QQMPR
1461
GNHFT
1466
IDEVK
1471
GTIYT
1476
NAEID
1481
REFAN
1486
LFELT
1491
VKAND
1496
QAVPI
1501
ETRRY
1506
ALKNV
1511
TILVT
1516
DLNDN
1521
VPMFI
1526
SQNAL
1531
AADPS
1536
AVIGS
1541
VLTTI
1546
MAADP
1551
DEGAN
1556
GEIEY
1561
EIING
1566
DTDTF
1571
IVDRY
1576
SGDLR
1581
VASAL
1586
VPSQL
1591
IYNLI
1596
VSATD
1601
LGPER
1606
RKSTT
1611
ELTII
1616
LQGLD
1621
GPVFT
1626
QPKYI
1631
TILKE
1636
GEPIG
1641
TNVIS
1646
IEAAS
1651
PRGSE
1656
APVEY
1661
YIVSV
1666
RCEEK
1671
TVGRL
1676
FTIGR
1681
HTGII
1686
QTAAI
1691
LDREQ
1696
GACLY
1701
LVDVY
1706
AIEKS
1711
TAFPR
1716
TQRAE
1721
VEITL
1726
QDIND
1731
NPPVF
1736
PTDML
1741
DLTVE
1746
ENIGD
1751
GSKIM
1756
QLTAM
1761
DADEG
1766
ANALV
1771
TYTII
1776
SGADD
1781
SFRID
1786
PESGD
1791
LIATR
1796
RLDRE
1801
RRSKY
1806
SLLVR
1811
ADDGL
1816
QSSDM
1821
RINIT
1826
VSDVN
1831
DHTPK
1836
FSRPV
1841
YSFDI
1846
PEDTI
1851
PGSLV
1856
AAILA
1861
TDDDS
1866
GVNGE
1871
ITYIV
1876
NEDDE
1881
DGIFF
1886
LNPIT
1891
GVFNL
1896
TRLLD
1901
YEVQQ
1906
YYILT
1911
VRAED
1916
GGGQF
1921
TTIRV
1926
YFNIL
1931
DVNDN
1936
PPIFS
1941
LNSYS
1946
TSLME
1951
NLPVG
1956
STVLV
1961
FNVTD
1966
ADDGI
1971
NSQLT
1976
YSIAS
1981
GDSLG
1986
QFTVD
1991
KNGVL
1996
KVLKA
2001
LDRES
2006
QSFYN
2011
LVVQV
2016
HDLPQ
2021
IPASR
2026
FTSTA
2031
QVSII
2036
LLDVN
2041
DNPPT
2046
FLSPK
2051
LTYIP
2056
ENTPI
2061
DTVVF
2066
KAQAT
2071
DPDSG
2076
PNSYI
2081
EYTLL
2086
NPLGN
2091
KFSIG
2096
TIDGE
2101
VRLTG
2106
ELDRE
2111
EVSNY
2116
TLTVV
2121
ATDKG
2126
QPSLS
2131
SSTEV
2136
VVMVL
2141
DINDN
2146
NPIFA
2151
QALYK
2156
VEINE
2161
NTLTG
2166
TDIIQ
2171
VFAAD
2176
GDEGT
2181
NGQVR
2186
YGIVN
2191
GNTNQ
2196
EFRID
2201
SVTGA
2206
ITVAK
2211
PLDRE
2216
KTPTY
2221
HLTVQ
2226
ATDRG
2231
STPRT
2236
DTSTV
2241
SIVLL
2246
DINDF
2251
VPVFE
2256
LSPYS
2261
VNVPE
2266
NLGTL
2271
PRTIL
2276
QVVAR
2281
DDDRG
2286
SNSKL
2291
SYVLF
2296
GGNED
2301
NAFTL
2306
SASGE
2311
LGVTQ
2316
SLDRE
2321
TKERF
2326
VLMIT
2331
ATDSG
2336
SPALT
2341
GTGTI
2346
NVIVD
2351
DVNDN
2356
VPTFA
2361
SKAYF
2366
TTIPE
2371
DAPTG
2376
TDVLL
2381
VNASD
2386
ADASK
2391
NAVIR
2396
IIGGN
2401
SQFTI
2406
NPSTG
2411
QIITS
2416
ALLDR
2421
ETKDN
2426
YTLVV
2431
VCSDA
2436
GSPEP
2441
LSSST
2446
SVLVT
2451
VTDVN
2456
DNPPR
2461
FQHHP
2466
YVTHI
2471
PSPTL
2476
PGSFV
2481
FAVTV
2486
TDADI
2491
GPNSE
2496
LHYSL
2501
SGRNS
2506
EKFHI
2511
DPLRG
2516
AIMAA
2521
GPLNG
2526
ASEVT
2531
FSVHV
2536
KDGGS
2541
FPKTD
2546
STTVT
2551
VRFVN
2556
KADFP
2561
KVRAK
2566
EQTFM
2571
FPENQ
2576
PVSSL
2581
VTTIT
2586
GSSLR
2591
GEPMS
2596
YYIAS
2601
GNLGN
2606
TFQID
2611
QLTGQ
2616
VSISQ
2621
PLDFE
2626
KIQKY
2631
VVWIE
2636
ARDGG
2641
FPPFS
2646
SYEKL
2651
DITVL
2656
DVNDN
2661
APIFK
2666
EDPFI
2671
SEILE
2676
NLSPR
2681
KILTV
2686
SAMDK
2691
DSGPN
2696
GQLDY
2701
EIVNG
2706
NMENS
2711
FSINH
2716
ATGEI
2721
RSVRP
2726
LDREK
2731
VSHYV
2736
LTIKS
2741
SDKGS
2746
PSQST
2751
SVKVM
2756
INILD
2761
ENDNA
2766
PRFSQ
2771
IFSAH
2776
VPENS
2781
PLGYT
2786
VTRVT
2791
TSDED
2796
IGINA
2801
ISRYS
2806
IMDAS
2811
LPFTI
2816
NPSTG
2821
DIVIS
2826
RPLNR
2831
EDTDR
2836
YRIRV
2841
SAHDS
2846
GWTVS
2851
TDVTI
2856
FVTDI
2861
NDNAP
2866
RFSRT
2871
SYYLD
2876
CPELT
2881
EIGSK
2886
VTQVF
2891
ATDPD
2896
EGSNG
2901
QVFYF
2906
IKSQS
2911
EYFRI
2916
NATTG
2921
EIFNK
2926
QILKY
2931
QNVTG
2936
FSNVN
2941
INRHS
2946
FIVTS
2951
SDRGK
2956
PSLIS
2961
ETTVT
2966
INIVD
2971
SNDNA
2976
PQFLK
2981
SKYFT
2986
PVTKN
2991
VKVGT
2996
KLIRV
3001
TAIDD
3006
KDFGL
3011
NSEVE
3016
YFISN
3021
DNHLG
3026
KFKLD
3031
NDTGW
3036
ISVAS
3041
SLISD
3046
LNQNF
3051
FITVT
3056
AKDKG
3061
NPPLS
3066
SQATV
3071
HITVT
3076
EENYH
3081
TPEFS
3086
QSHMS
3091
ATIPE
3096
SHSIG
3101
SIVRT
3106
VSARD
3111
RDAAM
3116
NGLIK
3121
YSISS
3126
GNEEG
3131
IFAIN
3136
SSTGI
3141
LTLAK
3146
ALDYE
3151
LCQKH
3156
EMTIS
3161
AIDGG
3166
WVART
3171
GYCSV
3176
TVNVI
3181
DVNDN
3186
SPVFL
3191
SDDYF
3196
PTVLE
3201
NAPSG
3206
TTVIH
3211
LNATD
3216
ADSGT
3221
NAVIA
3226
YTVQS
3231
SDSDL
3236
FVIDP
3241
NTGVI
3246
TTQGF
3251
LDFET
3256
KQSYH
3261
LTVKA
3266
FNVPD
3271
EERCS
3276
FATVN
3281
IQLKG
3286
TNEYV
3291
PRFVS
3296
KLYYF
3301
EISEA
3306
APKGT
3311
IVGEV
3316
FASDR
3321
DLGTD
3326
GEVHY
3331
LIFGN
3336
SRKKG
3341
FQINK
3346
KTGQI
3351
YVSGI
3356
LDREK
3361
EERVS
3366
LKVLA
3371
KNFGS
3376
IRGAD
3381
IDEVT
3386
VNVTV
3391
LDAND
3396
PPIFT
3401
LNIYS
3406
VQISE
3411
GVPIG
3416
THVTF
3421
VSAFD
3426
SDSIP
3431
SWSRF
3436
SYFIG
3441
SGNEN
3446
GAFSI
3451
NPQTG
3456
QITVT
3461
AELDR
3466
ETLPI
3471
YNLSV
3476
LAVDS
3481
GTPSA
3486
TGSAS
3491
LLVTL
3496
EDIND
3501
NGPML
3506
TVSEG
3511
EVMEN
3516
KRPGT
3521
LVMTL
3526
QSTDP
3531
DLPPN
3536
QGPFT
3541
YYLLS
3546
TGPAT
3551
SYFSL
3556
STAGV
3561
LSTTR
3566
EIDRE
3571
QIADF
3576
YLSVV
3581
TKDSG
3586
VPQMS
3591
STGTV
3596
HITVI
3601
DQNDN
3606
PSQSR
3611
TVEIF
3616
VNYYG
3621
NLFPG
3626
GILGS
3631
VKPQD
3636
PDVLD
3641
SFHCS
3646
LTSGV
3651
TSLFS
3656
IPGGT
3661
CDLNS
3666
QPRST
3671
DGTFD
3676
LTVLS
3681
NDGVH
3686
STVTS
3691
NIRVF
3696
FAGFS
3701
NATVD
3706
NSILL
3711
RLGVP
3716
TVKDF
3721
LTNHY
3726
LHFLR
3731
IASSQ
3736
LTGLG
3741
TAVQL
3746
YSAYE
3751
ENNRT
3756
FLLAA
3761
VKRNH
3766
NQYVN
3771
PSGVA
3776
TFFES
3781
IKEIL
3786
LRQSG
3791
VKVES
3796
VDHDS
3801
CVHGP
3806
CQNGG
3811
SCLRR
3816
LAVSS
3821
VLKSR
3826
ESLPV
3831
IIVAN
3836
EPLQP
3841
FLCKC
3846
LPGYA
3851
GSWCE
3856
IDIDE
3861
CLPSP
3866
CHSGG
3871
TCHNL
3876
VGGFS
3881
CSCPD
3886
GFTGR
3891
ACERD
3896
INECL
3901
QSPCK
3906
NGAIC
3911
QNFPG
3916
SFNCV
3921
CKTGY
3926
TGKMC
3931
ESSVN
3936
YCECN
3941
PCFNG
3946
GSCQS
3951
GVDSY
3956
YCHCP
3961
FGVFG
3966
KHCEL
3971
NSYGF
3976
EELSY
3981
MEFPS
3986
LDPNN
3991
NYIYV
3996
KFATI
4001
KSHAL
4006
LLYNY
4011
DNQTG
4016
DRAEF
4021
LALEI
4026
AEERL
4031
RFSYN
4036
LGSGT
4041
YKLTT
4046
MKKVS
4051
DGHFH
4056
TVIAR
4061
RAGMA
4066
ASLTV
4071
DSCSE
4076
NQEPG
4081
YCTVS
4086
NVAVS
4091
DDWTL
4096
DVQPN
4101
RVTVG
4106
GIRSL
4111
EPILQ
4116
RRGHV
4121
ESHDF
4126
VGCIM
4131
EFAVN
4136
GRPLE
4141
PSQAL
4146
AAQGI
4151
LDQCP
4156
RLEGA
4161
CTRSP
4166
CQHGG
4171
TCMDY
4176
WSWQQ
4181
CHCKE
4186
GLTGK
4191
YCEKS
4196
VTPDT
4201
ALSLE
4206
GKGRL
4211
DYHMS
4216
QNEKR
4221
EYLLR
4226
QSLRG
4231
AMLEP
4236
FGVNS
4241
LEVKF
4246
RTRSE
4251
NGVLI
4256
HIQES
4261
SNYTT
4266
VKIKN
4271
GKVYF
4276
TSDAG
4281
IAGKV
4286
ERNIP
4291
EVYVA
4296
DGHWH
4301
TFLIG
4306
KNGTA
4311
TVLSV
4316
DRIYN
4321
RDIIH
4326
PTQDF
4331
GGLDV
4336
LTISL
4341
GGIPP
4346
NQAHR
4351
DAQTA
4356
GFDGC
4361
IASMW
4366
YGGES
4371
LPFSG
4376
KHSLA
4381
SISKT
4386
DPSVK
4391
IGCRG
4396
PNICA
4401
SNPCW
4406
GDLLC
4411
INQWY
4416
AYRCV
4421
PPGDC
4426
ASHPC
4431
QNGGS
4436
CEPGL
4441
HSGFT
4446
CSCPD
4451
SHTGR
4456
TCEMV
4461
VACLG
4466
VLCPQ
4471
GKVCK
4476
AGSPA
4481
GHVCV
4486
LSQGP
4491
EEISL
4496
PLWAV
4501
PAIVG
4506
SCATV
4511
LALLV
4516
LSLIL
4521
CNQCR
4526
GKKAK
4531
NPKEE
4536
KKPKE
4541
KKKKG
4546
SENVA
4551
FDDPD
4556
NIPPY
4561
GDDMT
4566
VRKQP
4571
EGNPK
4576
PDIIE
4581
RENPY
4586
LIYDE
4591
TDIPH
4596
NSETI
4601
PSAPL
4606
ASPEQ
4611
EIEHY
4616
DIDNA
4621
SSIAP
4626
SDADI
4631
IQHYK
4636
QFRSH
4641
TPKFS
4646
IQRHS
4651
PLGFA
4656
RQSPM
4661
PLGAS
4666
SLTYQ
4671
PSYGQ
4676
GLRTS
4681
SLSHS
4686
ACPTP
4691
NPLSR
4696
HSPAP
4701
FSKSS
4706
TFYRN
4711
SPARE
4716
LHLPI
4721
RDGNT
4726
LEMHG
4731
DTCQP
4736
GIFNY
4741
ATRLG
4746
RRSKS
4751
PQAMA
4756
SHGSR
4761
PGSRL
4766
KQPIG
4771
QIPLE
4776
SSPPV
4781
GLSIE
4786
EVERL
4791
NTPRP
4796
RNPSI
4801
CSADH
4806
GRSSS
4811
EEDCR
4816
RPLSR
4821
TRNPA
4826
DGIPA
4831
PESSS
4836
DSDSH
4841
ESFTC
4846
SEMEY
4851
DREKP
4856
MVYTS
4861
RMPKL
4866
SQVNE
4871
SDADD
4876
EDNYG
4881
ARLKP
4886
RRYHG
4891
RRAEG
4896
GPVGT
4901
QAAAP
4906
GTADN
4911
TLPMK
4916
LGQQA
4921
GTFNW
4926
DNLLN
4931
WGPGF
4936
GHYVD
4941
VFKDL
4946
ASLPE
4951
KAAAN
4956
EEGKA
4961
GTTKP
4966
VPKDG
4971
EAEQY
4976
V
4981
Mutation Information
DNA mutation:
None
Peptide Range:
662 ~ 686
Mut AA position:
674 (13 in Wild Type peptide)
Alignment
Wild Type:
"TDLGSPPQSSMARINVSLLDINDNS
||||||||||||.||||||||||||
Mutant:
TDLGSPPQSSMACINVSLLDINDNS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) FAT4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay