Immunogenicity 6815

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CACNB3
Transcript ID
NM_001206917
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (471 aa)
MEGSA
1
DSYTS
6
RPSLD
11
SDVSL
16
EEDRE
21
SARRE
26
VESQA
31
QQQLE
36
RAKHK
41
PVAFA
46
VRTNV
51
SYCGV
56
LDEEC
61
PVQGS
66
GVNFE
71
AKDFL
76
HIKEK
81
YSNDW
86
WIGRL
91
VKEGG
96
DIAFI
101
PSPQR
106
LESIR
111
LKQEQ
116
KARRS
121
GNPSS
126
LSDIG
131
NRRSP
136
PPSLA
141
KQKQK
146
QAEHV
151
PPYDV
156
VPSMR
161
PVVLV
166
GPSLK
171
GYEVT
176
DMMQK
181
ALFDF
186
LKHRF
191
DGRIS
196
ITRVT
201
ADLSL
206
AKRSV
211
LNNPG
216
KRTII
221
ERSSA
226
RSSIA
231
EVQSE
236
IERIF
241
ELAKS
246
LQLVV
251
LDADT
256
INHPA
261
QLAKT
266
SLAPI
271
IVFVK
276
VSSPK
281
VLQRL
286
IRSRG
291
KSQMK
296
HLTVQ
301
MMAYD
306
KLVQC
311
PPESF
316
DVILD
321
ENQLE
326
DACEH
331
LAEYL
336
EVYWR
341
ATHHP
346
APGPG
351
LLGPP
356
SAIPG
361
LQNQQ
366
LLGER
371
GEEHS
376
PLERD
381
SLMPS
386
DEASE
391
SSRQA
396
WTGSS
401
QRSSR
406
HLEED
411
YADAY
416
QDLYQ
421
PHRQH
426
TSGLP
431
SANGH
436
DPQDR
441
LLAQD
446
SEHNH
451
SDRNW
456
QRNRP
461
WPKDS
466
Y
471
Mutation Information
DNA mutation:
None
Peptide Range:
169 ~ 193
Mut AA position:
181 (13 in Wild Type peptide)
Alignment
Wild Type:
"LVGPSLKGYEVTDMMQKALFDFLKH
||||||||||||.||||||||||||
Mutant:
LVGPSLKGYEVTEMMQKALFDFLKH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CACNB3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay