Immunogenicity 6853
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
AKAP2
Transcript ID
NM_001004065
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (948 aa)
MRWPQ
1
PGAAA
6
RLPPE
11
SPGPP
16
ESPGP
21
PEREA
26
AAARR
31
WTGAE
36
PQDCA
41
PGSGR
46
PEKPP
51
QLSED
56
DIWLK
61
SEGDN
66
YSATL
71
LEPAA
76
SSLSP
81
DHKNM
86
EIEVS
91
VAECK
96
SVPGI
101
TSTPH
106
PMDHP
111
SAFYS
116
PPHNG
121
LLTDH
126
HESLD
131
NDVAR
136
EIRYL
141
DEVLE
146
ANCCD
151
SAVDG
156
TYNGT
161
SSPEP
166
GAVVL
171
VGGLS
176
PPVHE
181
ATQPE
186
PTERT
191
ASRQA
196
PPHIE
201
LSNSS
206
PDPMA
211
EAERT
216
NGHSP
221
SQPRD
226
ALGDS
231
LQVPV
236
SPSST
241
TSSRC
246
SSRDG
251
EFTLT
256
TLKKE
261
AKFEL
266
RAFHE
271
DKKPS
276
KLFED
281
DEHEK
286
EQYCI
291
RKVRP
296
SEEML
301
ELEKE
306
RRELI
311
RSQAV
316
KKNPG
321
IAAKW
326
WNPPQ
331
EKTIE
336
EQLDE
341
EHLES
346
HKKYK
351
ERKER
356
RAQQE
361
QLLLQ
366
KQLQQ
371
QQQQP
376
PSQLC
381
TAPAS
386
SHERA
391
SMIDK
396
AKEDI
401
VTEQI
406
DFSAA
411
RKQFQ
416
LMENS
421
RQAVA
426
KGQST
431
PRLFS
436
IKPFY
441
RPLGS
446
VNSDK
451
PLTNP
456
RPPSV
461
GGPPE
466
DSGAS
471
AAKGQ
476
KSPGA
481
LETPS
486
AAGSQ
491
GNTAS
496
QGKEG
501
PYSEP
506
SKRGP
511
LSKLW
516
AEDGE
521
FTSAR
526
AVLTV
531
VKDDD
536
HGILD
541
QFSRS
546
VNVSL
551
TQEEL
556
DSGLD
561
ELSVR
566
SQDTT
571
VLETL
576
SNDFS
581
MDNIS
586
DSGAS
591
NETTN
596
ALQEN
601
SLADF
606
SLPQT
611
PQTDN
616
PSEGR
621
GEGVS
626
KSFSD
631
HGFYS
636
PSSTL
641
GDSPL
646
VDDPL
651
EYQAG
656
LLVQN
661
AIQQA
666
IAEQV
671
DKAVS
676
KTSRD
681
GAEQQ
686
GPEAT
691
VEEAE
696
AAAFG
701
SEKPQ
706
SMFEP
711
PQVSS
716
PVQEK
721
RDVLP
726
KILPA
731
EDRAL
736
RERGP
741
PQPLP
746
AVQPS
751
GPINM
756
EETRP
761
EGSYF
766
SKYSE
771
AAELR
776
STASL
781
LATQE
786
SDVMV
791
GPFKL
796
RSRKQ
801
RTLSM
806
IEEEI
811
RAAQE
816
REEEL
821
KRQRQ
826
VLQST
831
QSPRT
836
KNAPS
841
LPSRT
846
CYKTA
851
PGKIE
856
KVKPP
861
PSPTT
866
EGPSL
871
QPDLA
876
PEEAA
881
GTQRP
886
KNLMQ
891
TLMED
896
YETHK
901
SKRRE
906
RMDDS
911
SVLEA
916
TRVNR
921
RKSAL
926
ALRWE
931
AGIYA
936
NQEEE
941
DNE
946
Mutation Information
DNA mutation:
None
Peptide Range:
406 ~ 430
Mut AA position:
418 (13 in Wild Type peptide)
Alignment
Wild Type:
"VTEQIDFSAARKQFQLMENSRQAVA
||||||||||||.||||||||||||
Mutant:
VTEQIDFSAARKKFQLMENSRQAVA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) AKAP2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay