Immunogenicity 6869

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ARRDC1
Transcript ID
NM_152285
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (433 aa)
MGRVQ
1
LFEIS
6
LSHGR
11
VVYSP
16
GEPLA
21
GTVRV
26
RLGAP
31
LPFRA
36
IRVTC
41
IGSCG
46
VSNKA
51
NDTAW
56
VVEEG
61
YFNSS
66
LSLAD
71
KGSLP
76
AGEHS
81
FPFQF
86
LLPAT
91
APTSF
96
EGPFG
101
KIVHQ
106
VRAAI
111
HTPRF
116
SKDHK
121
CSLVF
126
YILSP
131
LNLNS
136
IPDIE
141
QPNVA
146
SATKK
151
FSYKL
156
VKTGS
161
VVLTA
166
STDLR
171
GYVVG
176
QALQL
181
HADVE
186
NQSGK
191
DTSPV
196
VASLL
201
QKVSY
206
KAKRW
211
IHDVR
216
TIAEV
221
EGAGV
226
KAWRR
231
AQWHE
236
QILVP
241
ALPQS
246
ALPGC
251
SLIHI
256
DYYLQ
261
VSLKA
266
PEATV
271
TLPVF
276
IGNIA
281
VNHAP
286
VSPRP
291
GLGLP
296
PGAPP
301
LVVPS
306
APPQE
311
EAEAE
316
AAAGG
321
PHFLD
326
PVFLS
331
TKSHS
336
QRQPL
341
LATLS
346
SVPGA
351
PEPCP
356
QDGSP
361
ASHPL
366
HPPLC
371
ISTGA
376
TVPYF
381
AEGSG
386
GPVPT
391
TSTLI
396
LPPEY
401
SSWGY
406
PYEAP
411
PSYEQ
416
SCGGV
421
EPSLT
426
PES
431
Mutation Information
DNA mutation:
None
Peptide Range:
16 ~ 40
Mut AA position:
28 (13 in Wild Type peptide)
Alignment
Wild Type:
"VVYSPGEPLAGTVRVRLGAPLPFRA
||||||||||||.||||||||||||
Mutant:
VVYSPGEPLAGTARVRLGAPLPFRA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ARRDC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay