Immunogenicity 69
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MBD5
Transcript ID
uc002twm.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1740 aa)
MNGGK
1
ECDGG
6
DKEGG
11
LPAIQ
16
VPVGW
21
QRRVD
26
QNGVL
31
YVSPS
36
GSLLS
41
CLEQV
46
KTYLL
51
TDGTC
56
KCGLE
61
CPLIL
66
PKVFN
71
FDPGA
76
AVKQR
81
TAEDV
86
KADED
91
VTKLC
96
IHKRK
101
IIAVA
106
TLHKS
111
MEAPH
116
PSLVL
121
TSPGG
126
GTNAT
131
PVVPS
136
RAATP
141
RSVRN
146
KSHEG
151
ITNSV
156
MPECK
161
NPFKL
166
MIGSS
171
NAMGR
176
LYVQE
181
LPGSQ
186
QQELH
191
PVYPR
196
QRLGS
201
SEHGQ
206
KSPFR
211
GSHGG
216
LPSPA
221
SSGSQ
226
IYGDG
231
SISPR
236
TDPLG
241
SPDVF
246
TRSNP
251
GFHGA
256
PNSSP
261
IHLNR
266
TPLSP
271
PSVML
276
HGSPV
281
QSSCA
286
MAGRT
291
NIPLS
296
PTLTT
301
KSPVM
306
KKPMC
311
NFSTN
316
MEIPR
321
AMFHH
326
KPPQG
331
PPPPP
336
PPSCA
341
LQKKP
346
LTSEK
351
DPLGI
356
LDPIP
361
SKPVN
366
QNPVI
371
INPTS
376
FHSNV
381
HSQVP
386
MMNVS
391
MPPAV
396
VPLPS
401
NLPLP
406
TVKPG
411
HMNHG
416
SHVQR
421
VQHSA
426
STSLS
431
PSPVT
436
SPVHM
441
MGTGI
446
GRIEA
451
SPQRS
456
RSSST
461
SSDHG
466
NFMMP
471
PVGPQ
476
ATSSG
481
IKVPP
486
RSPRS
491
TIGSP
496
RPSMP
501
SSPST
506
KSDGH
511
HQYKD
516
IPNPL
521
IAGIS
526
NVLNT
531
PSSAA
536
FPTAS
541
AGSSS
546
VKSQP
551
GLLGM
556
PLNQI
561
LNQHN
566
AASFP
571
ASSLL
576
SAAAK
581
AQLAN
586
QNKLA
591
GNNSS
596
SSSNS
601
GAVAG
606
SGNTE
611
GHSTL
616
NTMFP
621
PTANM
626
LLPTG
631
EGQSG
636
RAALR
641
DKLMS
646
QQKDA
651
LRKRK
656
QPPTT
661
VLSLL
666
RQSQM
671
DSSAV
676
PKPGP
681
DLLRK
686
QGQGS
691
FPISS
696
MSQLL
701
QSMSC
706
QSSHL
711
SSNST
716
PGCGA
721
SNTAL
726
PCSAN
731
QLHFT
736
DPSMN
741
SSVLQ
746
NIPLR
751
GEAVH
756
CHNAN
761
TNFVH
766
SNSPV
771
PNHHL
776
AGLIN
781
QIQAS
786
GNCGM
791
LSQSG
796
MALGN
801
SLHPN
806
PPQSR
811
ISTSS
816
TPVIP
821
NSIVS
826
SYNQT
831
SSEAG
836
GSGPS
841
SSIAI
846
AGTNH
851
PAITK
856
TTSVL
861
QDGVI
866
VTTAA
871
GNPLQ
876
SQLPI
881
GSDFP
886
FVGQE
891
HALHF
896
PSNST
901
SNNHL
906
PHPLN
911
PSLLS
916
SLPIS
921
LPVNQ
926
QHLLN
931
QNLLN
936
ILQPS
941
AGEGK
946
SEINL
951
HPLGF
956
LNPNV
961
NAALA
966
FLSSD
971
MDGQV
976
LQPVH
981
FQLLA
986
ALLQN
991
QAQAA
996
AMLPL
1001
PSFNL
1006
TISDL
1011
LQQQN
1016
TPLPS
1021
LTQMT
1026
APPDH
1031
LPSNQ
1036
SDNSR
1041
AETLL
1046
TSPLG
1051
NPLPS
1056
FAGSD
1061
TTFNP
1066
LFLPA
1071
VNGAS
1076
GLMTL
1081
NPQLL
1086
GGVLN
1091
SASAN
1096
TANHP
1101
EVSIA
1106
TSSQA
1111
TTTTT
1116
TTSSA
1121
VAALT
1126
VSTLG
1131
GTAVV
1136
SMAET
1141
LLNIS
1146
NNAGN
1151
TPGPA
1156
KLNSN
1161
SVVPQ
1166
LLNPL
1171
LGTGL
1176
LGDMS
1181
SINNT
1186
LSNHQ
1191
LTHLQ
1196
SLLNN
1201
NQMFP
1206
PNQQQ
1211
QQLLQ
1216
GYQNL
1221
QAFQG
1226
QSTIP
1231
CPANN
1236
NPMAC
1241
LFQNF
1246
QVRMQ
1251
EDAAL
1256
LNKRI
1261
STQPG
1266
LTALP
1271
ENPNT
1276
TLPPF
1281
QDTPC
1286
ELQPR
1291
IDPSL
1296
GQQVK
1301
DGLVV
1306
GGPGD
1311
ASVDA
1316
IYKAV
1321
VDAAS
1326
KGMQV
1331
VITTA
1336
VNSTT
1341
QISPI
1346
PALSA
1351
MSAFT
1356
ASIGD
1361
PLNLS
1366
SAVSA
1371
VIHGR
1376
NMGGV
1381
DHDGR
1386
LRNSR
1391
GARLP
1396
KNLDH
1401
GKNVN
1406
EGDGF
1411
EYFKS
1416
ASCHT
1421
SKKQW
1426
DGEQS
1431
PRGER
1436
NRWKY
1441
EEFLD
1446
HPGHI
1451
HSSPC
1456
HERPN
1461
NVSTL
1466
PFLPG
1471
EQHPI
1476
LLPPR
1481
NCPGD
1486
KILEE
1491
NFRYN
1496
NYKRT
1501
MMSFK
1506
ERLEN
1511
TVERC
1516
AHING
1521
NRPRQ
1526
SRGFG
1531
ELLST
1536
AKQDL
1541
VLEEQ
1546
SPSSS
1551
NSLEN
1556
SLVKD
1561
YIHYN
1566
GDFNA
1571
KSVNG
1576
CVPSP
1581
SDAKS
1586
ISSED
1591
DLRNP
1596
DSPSS
1601
NELIH
1606
YRPRT
1611
FNVGD
1616
LVWGQ
1621
IKGLT
1626
SWPGK
1631
LVRED
1636
DVHNS
1641
CQQSP
1646
EEGKV
1651
WVMWF
1656
GLHTF
1661
TQVEP
1666
EKLKT
1671
LTEGL
1676
EAYSR
1681
VRKRN
1686
RKSGK
1691
LNNHL
1696
EAAIH
1701
EAMSE
1706
LDKMS
1711
GTVHQ
1716
IPQGD
1721
RQMRP
1726
PKPKR
1731
RKISR
1736
Mutation Information
DNA mutation:
c.G2521A
Peptide Range:
829 ~ 853
Mut AA position:
841 (13 in Wild Type peptide)
Alignment
Wild Type:
"VSSYNQTSSEAGGSGPSSSIAIAGT
||||||||||||.||||||||||||
Mutant:
VSSYNQTSSEAGSSGPSSSIAIAGT"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) MBD5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VSSYNQTSSEAGSSGPSSSIAIAGT
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT