Immunogenicity 6928

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
TAF3
Transcript ID
NM_031923
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (929 aa)
MCESY
1
SRSLL
6
RVSVA
11
QICQA
16
LGWDS
21
VQLSA
26
CHLLT
31
DVLQR
36
YLQQL
41
GRGCH
46
RYSEL
51
YGRTD
56
PILDD
61
VGEAF
66
QLMGV
71
SLHEL
76
EDYIH
81
NIEPV
86
TFPHQ
91
IPSFP
96
VSKNN
101
VLQFP
106
QPGSK
111
DAEER
116
KEYIP
121
DYLPP
126
IVSSQ
131
EEEEE
136
EQVPT
141
DGGTS
146
AEAMQ
151
VPLEE
156
DDELE
161
EEEII
166
NDENF
171
LGKRP
176
LDSPE
181
AEELP
186
AMKRP
191
RLLST
196
KGDTL
201
DVVLL
206
EAREP
211
LSSIN
216
TQKIP
221
PMLSP
226
VHVQD
231
STDLA
236
PPSPE
241
PPMLA
246
PVAKS
251
QMPTA
256
KPLET
261
KSFTP
266
KTKTK
271
TSSPG
276
QKTKS
281
PKTAQ
286
SPAMV
291
GSPIR
296
SPKTV
301
SKEKK
306
SPGRS
311
KSPKS
316
PKSPK
321
VTTHI
326
PQTPV
331
RPETP
336
NRTPS
341
ATLSE
346
KISKE
351
TIQVK
356
QIQTP
361
PDAGK
366
LNSEN
371
QPKKA
376
VVADK
381
TIEAS
386
IDAVI
391
ARACA
396
EREPD
401
PFEFS
406
SGSES
411
EGDIF
416
TSPKR
421
ISGPE
426
CTTPK
431
ASTSA
436
NNFTK
441
SGSTP
446
LPLSG
451
GTSSS
456
DNSWT
461
MDASI
466
DEVVR
471
KAKLG
476
TPSNM
481
PPNFP
486
YISSP
491
SVSPP
496
TPEPL
501
HKVYE
506
EKTKL
511
PSSVE
516
VKKKL
521
KKELK
526
TKMKK
531
KEKQR
536
DRERE
541
KDKNK
546
DKSKE
551
KDKVK
556
EKEKD
561
KETGR
566
ETKYP
571
WKEFL
576
KEEEA
581
DPYKF
586
KIKEF
591
EDVDP
596
KVKLK
601
DGLVR
606
KEKEK
611
HKDKK
616
KDREK
621
GKKDK
626
DKREK
631
EKVKD
636
KGRED
641
KMKAP
646
APPLV
651
LPPKE
656
LALPL
661
FSPAT
666
ASRVP
671
AMLPS
676
LLPVL
681
PEKLF
686
EEKEK
691
VKEKE
696
KKKDK
701
KEKKK
706
KKEKE
711
KEKKE
716
KEREK
721
EKRER
726
EKREK
731
EKEKH
736
KHEKI
741
KVEPV
746
ALAPS
751
PVIPR
756
LTLRV
761
GAGQD
766
KIVIS
771
KVVPA
776
PEAKP
781
APSQN
786
RPKTP
791
PPAPA
796
PAPGP
801
MLVSP
806
APVPL
811
PLLAQ
816
AAAGP
821
ALLPS
826
PGPAA
831
SGASA
836
KAPVR
841
SVVTE
846
TVSTY
851
VIRDE
856
WGNQI
861
WICPG
866
CNKPD
871
DGSPM
876
IGCDD
881
CDDWY
886
HWPCV
891
GIMTA
896
PPEEM
901
QWFCP
906
KCANK
911
KKDKK
916
HKKRK
921
HRAH
926
Mutation Information
DNA mutation:
None
Peptide Range:
582 ~ 606
Mut AA position:
594 (13 in Wild Type peptide)
Alignment
Wild Type:
"EEEADPYKFKIKEFEDVDPKVKLKD
||||||||||||.||||||||||||
Mutant:
EEEADPYKFKIKQFEDVDPKVKLKD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TAF3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay