Immunogenicity 6936

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NELL1
Transcript ID
NM_201551
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (763 aa)
MPMDL
1
ILVVW
6
FCVCT
11
ARTVV
16
GFGMD
21
PDLQM
26
DIVTE
31
LDLVN
36
TTLGV
41
AQVSG
46
MHNAS
51
KAFLF
56
QDIER
61
EIHAA
66
PHVSE
71
KLIQL
76
FRNKS
81
EFTIL
86
ATVQQ
91
KPSTS
96
GVILS
101
IRELE
106
HSYFE
111
LESSG
116
LRDEI
121
RYHYI
126
HNGKP
131
RTEAL
136
PYRMA
141
DGQWH
146
KVALS
151
VSASH
156
LLLHV
161
DCNRI
166
YERVI
171
DPPDT
176
NLPPG
181
INLWL
186
GQRNQ
191
KHGLF
196
KGIIQ
201
DGKII
206
FMPNG
211
YITQC
216
PNLNH
221
TCPTC
226
SDFLS
231
LVQGI
236
MDLQE
241
LLAKM
246
TAKLN
251
YAETR
256
LSQLE
261
NCHCE
266
KTCQV
271
SGLLY
276
RDQDS
281
WVDGD
286
HCRNC
291
TCKSG
296
AVECR
301
RMSCP
306
PLNCS
311
PDSLP
316
VHIAG
321
QCCKV
326
CRPKC
331
IYGGK
336
VLAEG
341
QRILT
346
KSCRE
351
CRGGV
356
LVKIT
361
EMCPP
366
LNCSE
371
KDHIL
376
PENQC
381
CRVCR
386
GHNFC
391
AEGPK
396
CGENS
401
ECKNW
406
NTKAT
411
CECKS
416
GYISV
421
QGDSA
426
YCEDI
431
DECAA
436
KMHYC
441
HANTV
446
CVNLP
451
GLYRC
456
DCVPG
461
YIRVD
466
DFSCT
471
EHDEC
476
GSGQH
481
NCDEN
486
AICTN
491
TVQGH
496
SCTCK
501
PGYVG
506
NGTIC
511
RAFCE
516
EGCRY
521
GGTCV
526
APNKC
531
VCPSG
536
FTGSH
541
CEKDI
546
DECAL
551
RTHTC
556
WNDSA
561
CINLA
566
GGFDC
571
LCPSG
576
PSCSG
581
DCPHE
586
GGLKH
591
NGQVW
596
TLKED
601
RCSVC
606
SCKDG
611
KIFCR
616
RTACD
621
CQNPS
626
ADLFC
631
CPECD
636
TRVTS
641
QCLDQ
646
NGHKL
651
YRSGD
656
NWTHS
661
CQQCR
666
CLEGE
671
VDCWP
676
LTCPN
681
LSCEY
686
TAILE
691
GECCP
696
RCVSD
701
PCLAD
706
NITYD
711
IRKTC
716
LDSYG
721
VSRLS
726
GSVWT
731
MAGSP
736
CTTCK
741
CKNGR
746
VCCSV
751
DFECL
756
QNN
761
Mutation Information
DNA mutation:
None
Peptide Range:
404 ~ 428
Mut AA position:
416 (13 in Wild Type peptide)
Alignment
Wild Type:
"NSECKNWNTKATCECKSGYISVQGD
||||||||||||.||||||||||||
Mutant:
NSECKNWNTKATWECKSGYISVQGD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NELL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay