Immunogenicity 6971

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF91
Transcript ID
NM_003430
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (1191 aa)
MPGTP
1
GSLEM
6
GLLTF
11
RDVAI
16
EFSPE
21
EWQCL
26
DTAQQ
31
NLYRN
36
VMLEN
41
YRNLA
46
FLGIA
51
LSKPD
56
LITYL
61
EQGKE
66
PWNMK
71
QHEMV
76
DEPTG
81
ICPHF
86
PQDFW
91
PEQSM
96
EDSFQ
101
KVLLR
106
KYEKC
111
GHENL
116
QLRKG
121
CKSVD
126
ECKVH
131
KEGYN
136
KLNQC
141
LTTAQ
146
SKVFQ
151
CGKYL
156
KVFYK
161
FLNSN
166
RHTIR
171
HTGKK
176
CFKCK
181
KCVKS
186
FCIRL
191
HKTQH
196
KCVYI
201
TEKSC
206
KCKEC
211
EKTFH
216
WSSTL
221
TNHKE
226
IHTED
231
KPYKC
236
EECGK
241
AFKQL
246
STLTT
251
HKIIC
256
AKEKI
261
YKCEE
266
CGKAF
271
LWSST
276
LTRHK
281
RIHTG
286
EKPYK
291
CEECG
296
KAFSH
301
SSTLA
306
KHKRI
311
HTGEK
316
PYKCE
321
ECGKA
326
FSRSS
331
TLAKH
336
KRIHT
341
GEKPY
346
KCKEC
351
GKAFS
356
NSSTL
361
ANHKI
366
THTEE
371
KPYKC
376
KECDK
381
AFKRL
386
STLTK
391
HKIIH
396
AGEKL
401
YKCEE
406
CGKAF
411
NRSSN
416
LTIHK
421
FIHTG
426
EKPYK
431
CEECG
436
KAFNW
441
SSSLT
446
KHKRF
451
HTREK
456
PFKCK
461
ECGKA
466
FIWSS
471
TLTRH
476
KRIHT
481
GEKPY
486
KCEEC
491
GKAFR
496
QSSTL
501
TKHKI
506
IHTGE
511
KPYKF
516
EECGK
521
AFRQS
526
LTLNK
531
HKIIH
536
SREKP
541
YKCKE
546
CGKAF
551
KQFST
556
LTTHK
561
IIHAG
566
KKLYK
571
CEECG
576
KAFNH
581
SSSLS
586
THKII
591
HTGEK
596
SYKCE
601
ECGKA
606
FLWSS
611
TLRRH
616
KRIHT
621
GEKPY
626
KCEEC
631
GKAFS
636
HSSAL
641
AKHKR
646
IHTGE
651
KPYKC
656
KECGK
661
AFSNS
666
STLAN
671
HKITH
676
TEEKP
681
YKCKE
686
CDKTF
691
KRLST
696
LTKHK
701
IIHAG
706
EKLYK
711
CEECG
716
KAFNR
721
SSNLT
726
IHKFI
731
HTGEK
736
PYKCE
741
ECGKA
746
FNWSS
751
SLTKH
756
KRIHT
761
REKPF
766
KCKEC
771
GKAFI
776
WSSTL
781
TRHKR
786
IHTGE
791
KPYKC
796
EECGK
801
AFSRS
806
STLTK
811
HKTIH
816
TGEKP
821
YKCKE
826
CGKAF
831
KHSSA
836
LAKHK
841
IIHAG
846
EKLYK
851
CEECG
856
KAFNQ
861
SSNLT
866
THKII
871
HTKEK
876
PSKSE
881
ECDKA
886
FIWSS
891
TLTEH
896
KRIHT
901
REKTY
906
KCEEC
911
GKAFS
916
QPSHL
921
TTHKR
926
MHTGE
931
KPYKC
936
EECGK
941
AFSQS
946
STLTT
951
HKIIH
956
TGEKP
961
YKCEE
966
CGKAF
971
RKSST
976
LTEHK
981
IIHTG
986
EKPYK
991
CEECG
996
KAFSQ
1001
SSTLT
1006
RHTRM
1011
HTGEK
1016
PYKCE
1021
ECGKA
1026
FNRSS
1031
KLTTH
1036
KIIHT
1041
GEKPY
1046
KCEEC
1051
GKAFI
1056
SSSTL
1061
NGHKR
1066
IHTRE
1071
KPYKC
1076
EECGK
1081
AFSQS
1086
STLTR
1091
HKRLH
1096
TGEKP
1101
YKCGE
1106
CGKAF
1111
KESSA
1116
LTKHK
1121
IIHTG
1126
EKPYK
1131
CEKCG
1136
KAFNQ
1141
SSILT
1146
NHKKI
1151
HTITP
1156
VIPLL
1161
WEAEA
1166
GGSRG
1171
QEMET
1176
ILANT
1181
VKPLL
1186
Y
1191
Mutation Information
DNA mutation:
None
Peptide Range:
291 ~ 326
Mut AA position:
303 (13 in Wild Type peptide)
Alignment
Wild Type:
"EKPYKCEECGKAFSHSSTLAKHKRI------------
||||||||||||.| ||||.||||.
Mutant:
EKPYKCEECGKAYS-SSTLNKHKRLHTGEKPYKCEEC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF91

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay