Immunogenicity 6994

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TARS
Transcript ID
NM_001258438
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (756 aa)
MFEEK
1
ASSPS
6
GKMGG
11
EEKPI
16
GAGEE
21
KQKEG
26
GKKKN
31
KEGSG
36
DGGRA
41
ELNPW
46
PEYIY
51
TRLEM
56
YNILK
61
AEHDS
66
ILAEK
71
AEKDS
76
KPIKV
81
TLPDG
86
KQVDA
91
ESWKT
96
TPYQI
101
ACGIS
106
HTASC
111
KNLSS
116
LASLL
121
ASVAI
126
PSSGM
131
PWPPL
136
FFLQG
141
LADNT
146
VIAKV
151
NNVVW
156
DLDRP
161
LEEDC
166
TLELL
171
KFEDE
176
EAQAV
181
YWHSS
186
AHIMG
191
EAMER
196
VYGGC
201
LCYGP
206
PIENG
211
FYYDM
216
YLEEG
221
GVSSN
226
DFSSL
231
EALCK
236
KIIKE
241
KQAFE
246
RLEVK
251
KETLL
256
AMFKY
261
NKFKC
266
RILNE
271
KVNTP
276
TTTVY
281
RCGPL
286
IDLCR
291
GPHVR
296
HTGKI
301
KALKI
306
HKNSS
311
TYWEG
316
KADME
321
TLQRI
326
YGISF
331
PDPKM
336
LKEWE
341
KFQEE
346
AKNRD
351
HRKIG
356
RDQEL
361
YFFHE
366
LSPGS
371
CFFLP
376
KGAYI
381
YNALI
386
EFIRS
391
EYRKR
396
GFQEV
401
VTPNI
406
FNSRL
411
WMTSG
416
HWQHY
421
SENMF
426
SFEVE
431
KELFA
436
LKPMN
441
CPGHC
446
LMFDH
451
RPRSW
456
RELPL
461
RLADF
466
GVLHR
471
NELSG
476
ALTGL
481
TRVRR
486
FQQDD
491
AHIFC
496
AMEQI
501
EDEIK
506
GCLDF
511
LRTVY
516
SVFGF
521
SFKLN
526
LSTRP
531
EKFLG
536
DIEVW
541
DQAEK
546
QLENS
551
LNEFG
556
EKWEL
561
NSGDG
566
AFYGP
571
KIDIQ
576
IKDAI
581
GRYHQ
586
CATIQ
591
LDFQL
596
PIRFN
601
LTYVS
606
HDGDD
611
KKRPV
616
IVHRA
621
ILGSV
626
ERMIA
631
ILTEN
636
YGGKW
641
PFWLS
646
PRQVM
651
VVPVG
656
PTCDE
661
YAQKV
666
RQQFH
671
DAKFM
676
ADIDL
681
DPGCT
686
LNKKI
691
RNAQL
696
AQYNF
701
ILVVG
706
EKEKI
711
SGTVN
716
IRTRD
721
NKVHG
726
ERTIS
731
ETIER
736
LQQLK
741
EFRSK
746
QAEEE
751
F
756
Mutation Information
DNA mutation:
None
Peptide Range:
470 ~ 494
Mut AA position:
482 (13 in Wild Type peptide)
Alignment
Wild Type:
"FGVLHRNELSGALTGLTRVRRFQQD
||||||||||||.||||||||||||
Mutant:
FGVLHRNELSGAPTGLTRVRRFQQD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TARS

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay