Immunogenicity 7019

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
NFIC
Transcript ID
NM_001245002
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (508 aa)
MYSSP
1
LCLTQ
6
DEFHP
11
FIEAL
16
LPHVR
21
AFAYT
26
WFNLQ
31
ARKRK
36
YFKKH
41
EKRMS
46
KDEER
51
AVKDE
56
LLGEK
61
PEVKQ
66
KWASR
71
LLAKL
76
RKDIR
81
PECRE
86
DFVLS
91
ITGKK
96
APGCV
101
LSNPD
106
QKGKM
111
RRIDC
116
LRQAD
121
KVWRL
126
DLVMV
131
ILFKG
136
IPLES
141
TDGER
146
LVKAA
151
QCGHP
156
VLCVQ
161
PHHIG
166
VAVKE
171
LDLYL
176
AYFVR
181
ERDAE
186
QSGSP
191
RTGMG
196
SDQED
201
SKPIT
206
LDTTD
211
FQESF
216
VTSGV
221
FSVTE
226
LIQVS
231
RTPVV
236
TGTGP
241
NFSLG
246
ELQGH
251
LAYDL
256
NPAST
261
GLRRT
266
LPSTS
271
SSGSK
276
RHKSG
281
SMEED
286
VDTSP
291
GGDYY
296
TSPSS
301
PTSSS
306
RNWTE
311
DMEGG
316
ISSPV
321
KKTEM
326
DKSPF
331
NSPSP
336
QDSPR
341
LSSFT
346
QHHRP
351
VIAVH
356
SGIAR
361
SPHPS
366
SALHF
371
PTTSI
376
LPQTA
381
STYFP
386
HTAIR
391
YPPHL
396
NPQDP
401
LKDLV
406
SLACD
411
PASQQ
416
PGPLN
421
GSGQL
426
KMPSH
431
CLSAQ
436
MLAPP
441
PPGLP
446
RLALP
451
PATKP
456
ATTSE
461
GGATS
466
PTSPS
471
YSPPD
476
TSPAN
481
RSFVG
486
LGPRD
491
PAGIY
496
QAQSW
501
YLG
506
Mutation Information
DNA mutation:
None
Peptide Range:
284 ~ 308
Mut AA position:
296 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGSMEEDVDTSPGGDYYTSPSSPTS
||||||||||||.||||||||||||
Mutant:
SGSMEEDVDTSPVGDYYTSPSSPTS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NFIC

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay