Immunogenicity 7028
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
BOC
Transcript ID
NM_033254
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1114 aa)
MLRGT
1
MTAWR
6
GMRPE
11
VTLAC
16
LLLAT
21
AGCFA
26
DLNEV
31
PQVTV
36
QPAST
41
VQKPG
46
GTVIL
51
GCVVE
56
PPRMN
61
VTWRL
66
NGKEL
71
NGSDD
76
ALGVL
81
ITHGT
86
LVITA
91
LNNHT
96
VGRYQ
101
CVARM
106
PAGAV
111
ASVPA
116
TVTLA
121
NLQDF
126
KLDVQ
131
HVIEV
136
DEGNT
141
AVIAC
146
HLPES
151
HPKAQ
156
VRYSV
161
KQEWL
166
EASRG
171
NYLIM
176
PSGNL
181
QIVNA
186
SQEDE
191
GMYKC
196
AAYNP
201
VTQEV
206
KTSGS
211
SDRLR
216
VRRST
221
AEAAR
226
IIYPP
231
EAQTI
236
IVTKG
241
QSLIL
246
ECVAS
251
GIPPP
256
RVTWA
261
KDGSS
266
VTGYN
271
KTRFL
276
LSNLL
281
IDTTS
286
EEDSG
291
TYRCM
296
ADNGV
301
GQPGA
306
AVILY
311
NVQVF
316
EPPEV
321
TMELS
326
QLVIP
331
WGQSA
336
KLTCE
341
VRGNP
346
PPSVL
351
WLRNA
356
VPLIS
361
SQRLR
366
LSRRA
371
LRVLS
376
MGPED
381
EGVYQ
386
CMAEN
391
EVGSA
396
HAVVQ
401
LRTSR
406
PSITP
411
RLWQD
416
AELAT
421
GTPPV
426
SPSKL
431
GNPEQ
436
MLRGQ
441
PALPR
446
PPTSV
451
GPASP
456
QCPGE
461
KGQGA
466
PAEAP
471
IILSS
476
PRTSK
481
TDSYE
486
LVWRP
491
RHEGS
496
GRAPI
501
LYYVV
506
KHRKV
511
TNSSD
516
DWTIS
521
GIPAN
526
QHRLT
531
LTRLD
536
PGSLY
541
EVEMA
546
AYNCA
551
GEGQT
556
AMVTF
561
RTGRR
566
PKPEI
571
MASKE
576
QQIQR
581
DDPGA
586
SPQSS
591
SQPDH
596
GRLSP
601
PEAPD
606
RPTIS
611
TASET
616
SVYVT
621
WIPRG
626
NGGFP
631
IQSFR
636
VEYKK
641
LKKVG
646
DWILA
651
TSAIP
656
PSRLS
661
VEITG
666
LEKGT
671
SYKFR
676
VRALN
681
MLGES
686
EPSAP
691
SRPYV
696
VSGYS
701
GRVYE
706
RPVAG
711
PYITF
716
TDAVN
721
ETTIM
726
LKWMY
731
IPASN
736
NNTPI
741
HGFYI
746
YYRPT
751
DSDND
756
SDYKK
761
DMVEG
766
DKYWH
771
SISHL
776
QPETS
781
YDIKM
786
QCFNE
791
GGESE
796
FSNVM
801
ICETK
806
ARKSS
811
GQPGR
816
LPPPT
821
LAPPQ
826
PPLPE
831
TIERP
836
VGTGA
841
MVARS
846
SDLPY
851
LIVGV
856
VLGSI
861
VLIIV
866
TFIPF
871
CLWRA
876
WSKQK
881
HTTDL
886
GFPRS
891
ALPPS
896
CPYTM
901
VPLGG
906
LPGHQ
911
ASGQP
916
YLSGI
921
SGRAC
926
ANGIH
931
MNRGC
936
PSAAV
941
GYPGM
946
KPQQH
951
CPGEL
956
QQQSD
961
TSSLL
966
RQTHL
971
GNGYD
976
PQSHQ
981
ITRGP
986
KSSPD
991
EGSFL
996
YTLPD
1001
DSTHQ
1006
LLQPH
1011
HDCCQ
1016
RQEQP
1021
AAVGQ
1026
SGVRR
1031
APDSP
1036
VLEAV
1041
WDPPF
1046
HSGPP
1051
CCLGL
1056
VPVEE
1061
VDSPD
1066
SCQVS
1071
GGDWC
1076
PQHPV
1081
GAYVG
1086
QEPGM
1091
QLSPG
1096
PLVRV
1101
SFETP
1106
PLTI
1111
Mutation Information
DNA mutation:
None
Peptide Range:
244 ~ 268
Mut AA position:
256 (13 in Wild Type peptide)
Alignment
Wild Type:
"KGQSLILECVASGIPPPRVTWAKDG
||||||||||||.||||||||||||
Mutant:
KGQSLILECVASRIPPPRVTWAKDG"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) BOC
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay