Immunogenicity 7047

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
WDPCP
Transcript ID
NM_015910
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (746 aa)
MRREF
1
CWDAY
6
SKAAG
11
SRASS
16
PLPRQ
21
DRDSF
26
CHQMS
31
FCLTE
36
LHLWS
41
LKNTL
46
HIADR
51
DIGIY
56
QYYDK
61
KDPPA
66
TEHGN
71
LEKKQ
76
KLAES
81
RDYPW
86
TLKNR
91
RPEKL
96
RDSLK
101
ELEEL
106
MQNSR
111
CVLSK
116
WKNKY
121
VCQLL
126
FGSGV
131
LVSLS
136
LSGPQ
141
LEKVV
146
IDRSL
151
VGKLI
156
SDTIS
161
DALLT
166
DSFII
171
LSFLA
176
QNKLC
181
FIQFT
186
KKMES
191
SDVNK
196
RLEKL
201
SALDY
206
KIFYY
211
EIPGP
216
INKTT
221
ERHLA
226
INCVH
231
DRVVC
236
WWPLV
241
NDDAW
246
PWAPI
251
SSEKD
256
RANLL
261
LLGYA
266
QGRLE
271
VLSSV
276
RTEWD
281
PLDVR
286
FGTKQ
291
PYQVF
296
TVEHS
301
VSVDK
306
EPMAD
311
SCIYE
316
CIRNK
321
IQCVS
326
VTRIP
331
LKSKA
336
ISCCR
341
NVTED
346
KLILG
351
CEDSS
356
LILYE
361
THRRV
366
TLLAQ
371
TELLP
376
SLISC
381
HPSGA
386
ILLVG
391
SNQGE
396
LQIFD
401
MALSP
406
INIQL
411
LAEDR
416
LPRET
421
LQFSK
426
LFDAS
431
SSLVQ
436
MQWIA
441
PQVVS
446
QKGEG
451
SDIYD
456
LLFLR
461
FERGP
466
LGVLL
471
FKLGV
476
FTRGQ
481
LGLID
486
IIFQY
491
IHCDE
496
IYEAI
501
NILSS
506
MNWDT
511
LGHQC
516
FISMS
521
AIVNH
526
LLRQK
531
LTPER
536
EAQLE
541
TSLGT
546
FYAPT
551
RPLLD
556
STILE
561
YRDQI
566
SKYAR
571
RFFHH
576
LLRYQ
581
RFEKA
586
FLLAV
591
DVGAR
596
DLFMD
601
IHYLA
606
LDKGE
611
LALAE
616
VARKR
621
ASDID
626
AESIT
631
SGVEL
636
LGPLD
641
RGDML
646
NEAFI
651
GLSLA
656
PQGED
661
SFPDN
666
LPPSC
671
PTHRH
676
ILQQR
681
ILNGS
686
SNRQI
691
IDRRN
696
ELEKD
701
ICSGF
706
LMTNT
711
CNAED
716
GELRE
721
DGREQ
726
EIRDG
731
GSLKM
736
IHFGL
741
V
746
Mutation Information
DNA mutation:
None
Peptide Range:
323 ~ 347
Mut AA position:
335 (13 in Wild Type peptide)
Alignment
Wild Type:
"RNKIQCVSVTRIPLKSKAISCCRNV
||||||||||||.||||||||||||
Mutant:
RNKIQCVSVTRISLKSKAISCCRNV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) WDPCP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay