Immunogenicity 7078

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
AKR1B1
Transcript ID
NM_000044
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (920 aa)
MEVQL
1
GLGRV
6
YPRPP
11
SKTYR
16
GAFQN
21
LFQSV
26
REVIQ
31
NPGPR
36
HPEAA
41
SAAPP
46
GASLL
51
LLQQQ
56
QQQQQ
61
QQQQQ
66
QQQQQ
71
QQQQQ
76
ETSPR
81
QQQQQ
86
QGEDG
91
SPQAH
96
RRGPT
101
GYLVL
106
DEEQQ
111
PSQPQ
116
SALEC
121
HPERG
126
CVPEP
131
GAAVA
136
ASKGL
141
PQQLP
146
APPDE
151
DDSAA
156
PSTLS
161
LLGPT
166
FPGLS
171
SCSAD
176
LKDIL
181
SEAST
186
MQLLQ
191
QQQQE
196
AVSEG
201
SSSGR
206
AREAS
211
GAPTS
216
SKDNY
221
LGGTS
226
TISDN
231
AKELC
236
KAVSV
241
SMGLG
246
VEALE
251
HLSPG
256
EQLRG
261
DCMYA
266
PLLGV
271
PPAVR
276
PTPCA
281
PLAEC
286
KGSLL
291
DDSAG
296
KSTED
301
TAEYS
306
PFKGG
311
YTKGL
316
EGESL
321
GCSGS
326
AAAGS
331
SGTLE
336
LPSTL
341
SLYKS
346
GALDE
351
AAAYQ
356
SRDYY
361
NFPLA
366
LAGPP
371
PPPPP
376
PHPHA
381
RIKLE
386
NPLDY
391
GSAWA
396
AAAAQ
401
CRYGD
406
LASLH
411
GAGAA
416
GPGSG
421
SPSAA
426
ASSSW
431
HTLFT
436
AEEGQ
441
LYGPC
446
GGGGG
451
GGGGG
456
GGGGG
461
GGGGG
466
GGGEA
471
GAVAP
476
YGYTR
481
PPQGL
486
AGQES
491
DFTAP
496
DVWYP
501
GGMVS
506
RVPYP
511
SPTCV
516
KSEMG
521
PWMDS
526
YSGPY
531
GDMRL
536
ETARD
541
HVLPI
546
DYYFP
551
PQKTC
556
LICGD
561
EASGC
566
HYGAL
571
TCGSC
576
KVFFK
581
RAAEG
586
KQKYL
591
CASRN
596
DCTID
601
KFRRK
606
NCPSC
611
RLRKC
616
YEAGM
621
TLGAR
626
KLKKL
631
GNLKL
636
QEEGE
641
ASSTT
646
SPTEE
651
TTQKL
656
TVSHI
661
EGYEC
666
QPIFL
671
NVLEA
676
IEPGV
681
VCAGH
686
DNNQP
691
DSFAA
696
LLSSL
701
NELGE
706
RQLVH
711
VVKWA
716
KALPG
721
FRNLH
726
VDDQM
731
AVIQY
736
SWMGL
741
MVFAM
746
GWRSF
751
TNVNS
756
RMLYF
761
APDLV
766
FNEYR
771
MHKSR
776
MYSQC
781
VRMRH
786
LSQEF
791
GWLQI
796
TPQEF
801
LCMKA
806
LLLFS
811
IIPVD
816
GLKNQ
821
KFFDE
826
LRMNY
831
IKELD
836
RIIAC
841
KRKNP
846
TSCSR
851
RFYQL
856
TKLLD
861
SVQPI
866
ARELH
871
QFTFD
876
LLIKS
881
HMVSV
886
DFPEM
891
MAEII
896
SVQVP
901
KILSG
906
KVKPI
911
YFHTQ
916
Mutation Information
DNA mutation:
None
Peptide Range:
265 ~ 289
Mut AA position:
277 (13 in Wild Type peptide)
Alignment
Wild Type:
"GDCMYAPLLGVPPAVRPTPCAPLAE
||||||||||||.||||||||||||
Mutant:
GDCMYAPLLGVPSAVRPTPCAPLAE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AR

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay