Immunogenicity 7084

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
CFH
Transcript ID
NM_000186
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (1231 aa)
MRLLA
1
KIICL
6
MLWAI
11
CVAED
16
CNELP
21
PRRNT
26
EILTG
31
SWSDQ
36
TYPEG
41
TQAIY
46
KCRPG
51
YRSLG
56
NVIMV
61
CRKGE
66
WVALN
71
PLRKC
76
QKRPC
81
GHPGD
86
TPFGT
91
FTLTG
96
GNVFE
101
YGVKA
106
VYTCN
111
EGYQL
116
LGEIN
121
YRECD
126
TDGWT
131
NDIPI
136
CEVVK
141
CLPVT
146
APENG
151
KIVSS
156
AMEPD
161
REYHF
166
GQAVR
171
FVCNS
176
GYKIE
181
GDEEM
186
HCSDD
191
GFWSK
196
EKPKC
201
VEISC
206
KSPDV
211
INGSP
216
ISQKI
221
IYKEN
226
ERFQY
231
KCNMG
236
YEYSE
241
RGDAV
246
CTESG
251
WRPLP
256
SCEEK
261
SCDNP
266
YIPNG
271
DYSPL
276
RIKHR
281
TGDEI
286
TYQCR
291
NGFYP
296
ATRGN
301
TAKCT
306
STGWI
311
PAPRC
316
TLKPC
321
DYPDI
326
KHGGL
331
YHENM
336
RRPYF
341
PVAVG
346
KYYSY
351
YCDEH
356
FETPS
361
GSYWD
366
HIHCT
371
QDGWS
376
PAVPC
381
LRKCY
386
FPYLE
391
NGYNQ
396
NHGRK
401
FVQGK
406
SIDVA
411
CHPGY
416
ALPKA
421
QTTVT
426
CMENG
431
WSPTP
436
RCIRV
441
KTCSK
446
SSIDI
451
ENGFI
456
SESQY
461
TYALK
466
EKAKY
471
QCKLG
476
YVTAD
481
GETSG
486
SITCG
491
KDGWS
496
AQPTC
501
IKSCD
506
IPVFM
511
NARTK
516
NDFTW
521
FKLND
526
TLDYE
531
CHDGY
536
ESNTG
541
STTGS
546
IVCGY
551
NGWSD
556
LPICY
561
ERECE
566
LPKID
571
VHLVP
576
DRKKD
581
QYKVG
586
EVLKF
591
SCKPG
596
FTIVG
601
PNSVQ
606
CYHFG
611
LSPDL
616
PICKE
621
QVQSC
626
GPPPE
631
LLNGN
636
VKEKT
641
KEEYG
646
HSEVV
651
EYYCN
656
PRFLM
661
KGPNK
666
IQCVD
671
GEWTT
676
LPVCI
681
VEEST
686
CGDIP
691
ELEHG
696
WAQLS
701
SPPYY
706
YGDSV
711
EFNCS
716
ESFTM
721
IGHRS
726
ITCIH
731
GVWTQ
736
LPQCV
741
AIDKL
746
KKCKS
751
SNLII
756
LEEHL
761
KNKKE
766
FDHNS
771
NIRYR
776
CRGKE
781
GWIHT
786
VCING
791
RWDPE
796
VNCSM
801
AQIQL
806
CPPPP
811
QIPNS
816
HNMTT
821
TLNYR
826
DGEKV
831
SVLCQ
836
ENYLI
841
QEGEE
846
ITCKD
851
GRWQS
856
IPLCV
861
EKIPC
866
SQPPQ
871
IEHGT
876
INSSR
881
SSQES
886
YAHGT
891
KLSYT
896
CEGGF
901
RISEE
906
NETTC
911
YMGKW
916
SSPPQ
921
CEGLP
926
CKSPP
931
EISHG
936
VVAHM
941
SDSYQ
946
YGEEV
951
TYKCF
956
EGFGI
961
DGPAI
966
AKCLG
971
EKWSH
976
PPSCI
981
KTDCL
986
SLPSF
991
ENAIP
996
MGEKK
1001
DVYKA
1006
GEQVT
1011
YTCAT
1016
YYKMD
1021
GASNV
1026
TCINS
1031
RWTGR
1036
PTCRD
1041
TSCVN
1046
PPTVQ
1051
NAYIV
1056
SRQMS
1061
KYPSG
1066
ERVRY
1071
QCRSP
1076
YEMFG
1081
DEEVM
1086
CLNGN
1091
WTEPP
1096
QCKDS
1101
TGKCG
1106
PPPPI
1111
DNGDI
1116
TSFPL
1121
SVYAP
1126
ASSVE
1131
YQCQN
1136
LYQLE
1141
GNKRI
1146
TCRNG
1151
QWSEP
1156
PKCLH
1161
PCVIS
1166
REIME
1171
NYNIA
1176
LRWTA
1181
KQKLY
1186
SRTGE
1191
SVEFV
1196
CKRGY
1201
RLSSR
1206
SHTLR
1211
TTCWD
1216
GKLEY
1221
PTCAK
1226
R
1231
Mutation Information
DNA mutation:
None
Peptide Range:
571 ~ 595
Mut AA position:
583 (13 in Wild Type peptide)
Alignment
Wild Type:
"LPKIDVHLVPDRKKDQYKVGEVLKF
||||||||||||.||||||||||||
Mutant:
LPKIDVHLVPDRRKDQYKVGEVLKF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CFH

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay