Immunogenicity 7092
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ADCY1
Transcript ID
NM_021116
HLA INFO
B*44:03
TCR INFO
No TCR info found!
Full length protein sequence (1119 aa)
MAGAP
1
RGGGG
6
GGGGA
11
GEPGG
16
AERAA
21
GTSRR
26
RGLRA
31
CDEEF
36
ACPEL
41
EALFR
46
GYTLR
51
LEQAA
56
TLKAL
61
AVLSL
66
LAGAL
71
ALAEL
76
LGAPG
81
PAPGL
86
AKGSH
91
PVHCV
96
LFLAL
101
LVVTN
106
VRSLQ
111
VPQLQ
116
QVGQL
121
ALLFS
126
LTFAL
131
LCCPF
136
ALGGP
141
ARGSA
146
GAAGG
151
PATAE
156
QGVWQ
161
LLLVT
166
FVSYA
171
LLPVR
176
SLLAI
181
GFGLV
186
VAASH
191
LLVTA
196
TLVPA
201
KRPRL
206
WRTLG
211
ANALL
216
FVGVN
221
MYGVF
226
VRILT
231
ERSQR
236
KAFLQ
241
ARSCI
246
EDRLR
251
LEDEN
256
EKQER
261
LLMSL
266
LPRNV
271
AMEMK
276
EDFLK
281
PPERI
286
FHKIY
291
IQRHD
296
NVSIL
301
FADIV
306
GFTGL
311
ASQCT
316
AQELV
321
KLLNE
326
LFGKF
331
DELAT
336
ENHCR
341
RIKIL
346
GDCYY
351
CVSGL
356
TQPKT
361
DHAHC
366
CVEMG
371
LDMID
376
TITSV
381
AEATE
386
VDLNM
391
RVGLH
396
TGRVL
401
CGVLG
406
LRKWQ
411
YDVWS
416
NDVTL
421
ANVME
426
AAGLP
431
GKVHI
436
TKTTL
441
ACLNG
446
DYEVE
451
PGYGH
456
ERNSF
461
LKTHN
466
IETFF
471
IVPSH
476
RRKIF
481
PGLIL
486
SDIKP
491
AKRMK
496
FKTVC
501
YLLVQ
506
LMHCR
511
KMFKA
516
EIPFS
521
NVMTC
526
EDDDK
531
RRALR
536
TASEK
541
LRNRS
546
SFSTN
551
VVYTT
556
PGTRV
561
NRYIS
566
RLLEA
571
RQTEL
576
EMADL
581
NFFTL
586
KYKHV
591
EREQK
596
YHQLQ
601
DEYFT
606
SAVVL
611
TLILA
616
ALFGL
621
VYLLI
626
FPQSV
631
VVLLL
636
LVFCI
641
CFLVA
646
CVLYL
651
HITRV
656
QCFPG
661
CLTIQ
666
IRTVL
671
CIFIV
676
VLIYS
681
VAQGC
686
VVGCL
691
PWAWS
696
SKPNS
701
SLVVL
706
SSGGQ
711
RTALP
716
TLPCE
721
STHHA
726
LLCCL
731
VGTLP
736
LAIFF
741
RVSSL
746
PKMIL
751
LSGLT
756
TSYIL
761
VLELS
766
GYTRT
771
GGGAV
776
SGRSY
781
EPIVA
786
ILLFS
791
CALAL
796
HARQV
801
DIRLR
806
LDYLW
811
AAQAE
816
EERED
821
MEKVK
826
LDNRR
831
ILFNL
836
LPAHV
841
AQHFL
846
MSNPR
851
NMDLY
856
YQSYS
861
QVGVM
866
FASIP
871
NFNDF
876
YIELD
881
GNNMG
886
VECLR
891
LLNEI
896
IADFD
901
ELMEK
906
DFYKD
911
IEKIK
916
TIGST
921
YMAAV
926
GLAPT
931
SGTKA
936
KKSIS
941
SHLST
946
LADFA
951
IEMFD
956
VLDEI
961
NYQSY
966
NDFVL
971
RVGIN
976
VGPVV
981
AGVIG
986
ARRPQ
991
YDIWG
996
NTVNV
1001
ASRMD
1006
STGVQ
1011
GRIQV
1016
TEEVH
1021
RLLRR
1026
CPYHF
1031
VCRGK
1036
VSVKG
1041
KGEML
1046
TYFLE
1051
GRTDG
1056
NGSQI
1061
RSLGL
1066
DRKMC
1071
PFGRA
1076
GLQGR
1081
RPPVC
1086
PMPGV
1091
SVRAG
1096
LPPHS
1101
PGQYL
1106
PSAAA
1111
GKEA
1116
Mutation Information
DNA mutation:
None
Peptide Range:
333 ~ 357
Mut AA position:
345 (13 in Wild Type peptide)
Alignment
Wild Type:
"GKFDELATENHCRRIKILGDCYYCV
||||||||||||.||||||||||||
Mutant:
GKFDELATENHCHRIKILGDCYYCV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ADCY1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay