Immunogenicity 710

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
RAPGEF2
Transcript ID
ENST00000505478
HLA INFO
B*18:01
TCR INFO

No TCR info found!

T cell Tumor cell B*18:01
sequence
Full length protein sequence (279 aa)
DNSFR
1
QAVMK
6
NPPER
11
TPQDL
16
EIVYS
21
YLHGM
26
EALSN
31
LREHQ
36
LRLMC
41
ETVRY
46
ERHEA
51
NEVLY
56
YPDDI
61
GTCWY
66
ILLSG
71
SVFIK
76
ESMFL
81
PRSSF
86
GKRSA
91
GSFRR
96
GCECI
101
VLEPS
106
EMIVV
111
DYMDE
116
NEEYF
121
QRQAS
126
HRQSR
131
RRFRK
136
INQKG
141
ERQTI
146
IDTVD
151
PYPMG
156
KPPLP
161
RGYHT
166
ECTKS
171
QLPAD
176
FTKLH
181
LTDSL
186
HPQVT
191
HVSSS
196
HSGCS
201
ITSDS
206
GSSSL
211
SDIYQ
216
ATESE
221
AGDMD
226
LSGLP
231
ETAVD
236
SEDDD
241
DEEDI
246
ERASD
251
PLMSR
256
DIVRD
261
CLEKD
266
PIDRT
271
DDDI
276
Mutation Information
DNA mutation:
None
Peptide Range:
2 ~ 26
Mut AA position:
14 (13 in Wild Type peptide)
Alignment
Wild Type:
"NSFRQAVMKNPPERTPQDLEIVYSY
||||||||||||.||||||||||||
Mutant:
NSFRQAVMKNPPQRTPQDLEIVYSY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000109756

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay