Immunogenicity 7107

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GPR149
Transcript ID
NM_001038705
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (731 aa)
MSLFL
1
SNLST
6
NDSSL
11
WKENH
16
NSTDL
21
LNPPG
26
TLNIY
31
LFCLT
36
CLMTF
41
AALVG
46
SIYSL
51
ISLLK
56
MQNRT
61
VVSML
66
VASWS
71
VDDLM
76
SVLSV
81
TIFMF
86
LQWPN
91
EVPGY
96
FQFLC
101
TTSAL
106
MYLCQ
111
GLSSN
116
LKATL
121
LVSYN
126
FYTMH
131
RGVGS
136
QTASR
141
RSGQV
146
LGVVL
151
TVWAA
156
SLLLS
161
ALPLC
166
GWGAF
171
VRTPW
176
GCLVD
181
CSSSY
186
VLFLS
191
IVYAL
196
AFGLL
201
VGLSV
206
PLTHR
211
LLCSE
216
EPPRL
221
HSNYQ
226
EISRG
231
ASIPG
236
TPPTA
241
GRVVS
246
LSPED
251
APGPS
256
LRRSG
261
GCSPS
266
SDTVF
271
GPGAP
276
AAAGA
281
EACRR
286
ENRGT
291
LYGTR
296
SFTVS
301
VAQKR
306
FALIL
311
ALTKV
316
VLWLP
321
MMMHM
326
VVQNV
331
VGFQS
336
LPLET
341
FSFLL
346
TLLAT
351
TVTPV
356
FVLSK
361
RWTHL
366
PCGCI
371
INCRQ
376
NAYAV
381
ASDGK
386
KIKRK
391
GFEFN
396
LSFQK
401
SYGIY
406
KIAHE
411
DYYDD
416
DENSI
421
FYHNL
426
MNSEC
431
ETTKD
436
PQRDN
441
RNIFN
446
AIKVE
451
ISTTP
456
SLDSS
461
TQRGI
466
NKCTN
471
TDITE
476
AKQDS
481
NNKKD
486
AFSDK
491
TGGDI
496
NYEET
501
TFSEG
506
PERRL
511
SHEES
516
QKPDL
521
SDWEW
526
CRSKS
531
ERTPR
536
QRSGY
541
ALAIP
546
LCAFQ
551
GTVSL
556
HAPTG
561
KTLSL
566
STYEV
571
SAEGQ
576
KITPA
581
SKKIE
586
VYRSK
591
SVGHE
596
PNSED
601
SSSTF
606
VDTSV
611
KIHLE
616
VLEIC
621
DNEEA
626
LDTVS
631
IISNI
636
SQSST
641
QVRSP
646
SLRYS
651
RKENR
656
FVSCD
661
LGETA
666
SYSLF
671
LPTSN
676
PDGDI
681
NISIP
686
DTVEA
691
HRQNS
696
KRQHQ
701
ERDGY
706
QEEIQ
711
LLNKA
716
YRKRE
721
EESKG
726
S
731
Mutation Information
DNA mutation:
None
Peptide Range:
339 ~ 363
Mut AA position:
351 (13 in Wild Type peptide)
Alignment
Wild Type:
"QSLPLETFSFLLTLLATTVTPVFVL
||||||||||||.||||||||||||
Mutant:
QSLPLETFSFLLILLATTVTPVFVL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GPR149

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay