Immunogenicity 7142

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ARRB2
Transcript ID
NM_004313
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (409 aa)
MGEKP
1
GTRVF
6
KKSSP
11
NCKLT
16
VYLGK
21
RDFVD
26
HLDKV
31
DPVDG
36
VVLVD
41
PDYLK
46
DRKVF
51
VTLTC
56
AFRYG
61
REDLD
66
VLGLS
71
FRKDL
76
FIATY
81
QAFPP
86
VPNPP
91
RPPTR
96
LQDRL
101
LRKLG
106
QHAHP
111
FFFTI
116
PQNLP
121
CSVTL
126
QPGPE
131
DTGKA
136
CGVDF
141
EIRAF
146
CAKSL
151
EEKSH
156
KRNSV
161
RLVIR
166
KVQFA
171
PEKPG
176
PQPSA
181
ETTRH
186
FLMSD
191
RSLHL
196
EASLD
201
KELYY
206
HGEPL
211
NVNVH
216
VTNNS
221
TKTVK
226
KIKVS
231
VRQYA
236
DICLF
241
STAQY
246
KCPVA
251
QLEQD
256
DQVSP
261
SSTFC
266
KVYTI
271
TPLLS
276
DNREK
281
RGLAL
286
DGKLK
291
HEDTN
296
LASST
301
IVKEG
306
ANKEV
311
LGILV
316
SYRVK
321
VKLVV
326
SRGGD
331
VSVEL
336
PFVLM
341
HPKPH
346
DHIPL
351
PRPQS
356
AAPET
361
DVPVD
366
TNLIE
371
FDTNY
376
ATDDD
381
IVFED
386
FARLR
391
LKGMK
396
DDDYD
401
DQLC
406
Mutation Information
DNA mutation:
None
Peptide Range:
40 ~ 64
Mut AA position:
52 (13 in Wild Type peptide)
Alignment
Wild Type:
"GVVLVDPDYLKDRKVFVTLTCAFRY
||||||||||||.||||||||||||
Mutant:
GVVLVDPDYLKDCKVFVTLTCAFRY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ARRB2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay