Immunogenicity 7156

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ATXN7
Transcript ID
NM_000333
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (892 aa)
MSERA
1
ADDVR
6
GEPRR
11
AAAAA
16
GGAAA
21
AAARQ
26
QQQQQ
31
QQQQP
36
PPPQP
41
QRQQH
46
PPPPP
51
RRTRP
56
EDGGP
61
GAAST
66
SAAAM
71
ATVGE
76
RRPLP
81
SPEVM
86
LGQSW
91
NLWVE
96
ASKLP
101
GKDGT
106
ELDES
111
FKEFG
116
KNREV
121
MGLCR
126
EDMPI
131
FGFCP
136
AHDDF
141
YLVVC
146
NDCNQ
151
VVKPQ
156
AFQSH
161
YERRH
166
SSSSK
171
PPLAV
176
PPTSV
181
FSFFP
186
SLSKS
191
KGGSA
196
SGSNR
201
SSSGG
206
VLSAS
211
SSSSK
216
LLKSP
221
KEKLQ
226
LRGNT
231
RPMHP
236
IQQSR
241
VPHGR
246
IMTPS
251
VKVEK
256
IHPKM
261
DGTLL
266
KSAVG
271
PTCPA
276
TVSSL
281
VKPGL
286
NCPSI
291
PKPTL
296
PSPGQ
301
ILNGK
306
GLPAP
311
PTLEK
316
KPEDN
321
SNNRK
326
FLNKR
331
LSERE
336
FDPDI
341
HCGVI
346
DLDTK
351
KPCTR
356
SLTCK
361
THSLT
366
QRRAV
371
QGRRK
376
RFDVL
381
LAEHK
386
NKTRE
391
KELIR
396
HPDSQ
401
QPPQP
406
LRDPH
411
PAPPR
416
TSQEP
421
HQNPH
426
GVIPS
431
ESKPF
436
VASKP
441
KPHTP
446
SLPRP
451
PGCPA
456
QQGGS
461
APIDP
466
PPVHE
471
SPHPP
476
LPATE
481
PASRL
486
SSEEG
491
EGDDK
496
EESVE
501
KLDCH
506
YSGHH
511
PQPAS
516
FCTFG
521
SRQIG
526
RGYYV
531
FDSRW
536
NRLRC
541
ALNLM
546
VEKHL
551
NAQLW
556
KKIPP
561
VPSTT
566
SPIST
571
RIPHR
576
TNSVP
581
TSQCG
586
VSYLA
591
AATVS
596
TSPVL
601
LSSTC
606
ISPNS
611
KSVPA
616
HGTTL
621
NAQPA
626
ASGAM
631
DPVCS
636
MQSRQ
641
VSSSS
646
SSPST
651
PSGLS
656
SVPSS
661
PMSRK
666
PQKLK
671
SSKSL
676
RPKES
681
SGNST
686
NCQNA
691
SSSTS
696
GGSGK
701
KRKNS
706
SPLLV
711
HSSSS
716
SSSSS
721
SSSHS
726
MESFR
731
KNCVA
736
HSGPP
741
YPSTV
746
TSSHS
751
IGLNC
756
VTNKA
761
NAVNV
766
RHDQS
771
GRGPP
776
TGSPA
781
ESIKR
786
MSVMV
791
NSSDS
796
TLSLG
801
PFIHQ
806
SNELP
811
VNSHG
816
SFSHS
821
HTPLD
826
KLIGK
831
KRKCS
836
PSSSS
841
INNSS
846
SKPTK
851
VAKVP
856
AVNNV
861
HMKHT
866
GTIPG
871
AQGLM
876
NSSLL
881
HQPKA
886
RP
891
Mutation Information
DNA mutation:
None
Peptide Range:
17 ~ 41
Mut AA position:
29 (13 in Wild Type peptide)
Alignment
Wild Type:
"AAAAGGAAAAAARQQQQQQQQQQPP
||||||||||||.||||||||||||
Mutant:
AAAAGGAAAAAAPQQQQQQQQQQPP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ATXN7

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay