Immunogenicity 7192

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DLD
Transcript ID
NM_000108
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (509 aa)
MQSWS
1
RVYCS
6
LAKRG
11
HFNRI
16
SHGLQ
21
GLSAV
26
PLRTY
31
ADQPI
36
DADVT
41
VIGSG
46
PGGYV
51
AAIKA
56
AQLGF
61
KTVCI
66
EKNET
71
LGGTC
76
LNVGC
81
IPSKA
86
LLNNS
91
HYYHM
96
AHGKD
101
FASRG
106
IEMSE
111
VRLNL
116
DKMME
121
QKSTA
126
VKALT
131
GGIAH
136
LFKQN
141
KVVHV
146
NGYGK
151
ITGKN
156
QVTAT
161
KADGG
166
TQVID
171
TKNIL
176
IATGS
181
EVTPF
186
PGITI
191
DEDTI
196
VSSTG
201
ALSLK
206
KVPEK
211
MVVIG
216
AGVIG
221
VELGS
226
VWQRL
231
GADVT
236
AVEFL
241
GHVGG
246
VGIDM
251
EISKN
256
FQRIL
261
QKQGF
266
KFKLN
271
TKVTG
276
ATKKS
281
DGKID
286
VSIEA
291
ASGGK
296
AEVIT
301
CDVLL
306
VCIGR
311
RPFTK
316
NLGLE
321
ELGIE
326
LDPRG
331
RIPVN
336
TRFQT
341
KIPNI
346
YAIGD
351
VVAGP
356
MLAHK
361
AEDEG
366
IICVE
371
GMAGG
376
AVHID
381
YNCVP
386
SVIYT
391
HPEVA
396
WVGKS
401
EEQLK
406
EEGIE
411
YKVGK
416
FPFAA
421
NSRAK
426
TNADT
431
DGMVK
436
ILGQK
441
STDRV
446
LGAHI
451
LGPGA
456
GEMVN
461
EAALA
466
LEYGA
471
SCEDI
476
ARVCH
481
AHPTL
486
SEAFR
491
EANLA
496
ASFGK
501
SINF
506
Mutation Information
DNA mutation:
None
Peptide Range:
130 ~ 154
Mut AA position:
142 (13 in Wild Type peptide)
Alignment
Wild Type:
"AVKALTGGIAHLFKQNKVVHVNGYG
||||||||||||.||||||||||||
Mutant:
AVKALTGGIAHLLKQNKVVHVNGYG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DLD

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay