Immunogenicity 722

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CEACAM1
Transcript ID
ENST00000599389
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (399 aa)
MGHLS
1
APLHR
6
VRVPW
11
QGLLL
16
TASLL
21
TFWNP
26
PTTAQ
31
LTTES
36
MPFNV
41
AEGKE
46
VLLLV
51
HNLPQ
56
QLFGY
61
SWYKG
66
ERVDG
71
NRQIV
76
GYAIG
81
TQQAT
86
PGPAN
91
SGRET
96
IYPNA
101
SLLIQ
106
NVTQN
111
DTGFY
116
TLQVI
121
KSDLV
126
NEEAT
131
GQFHV
136
YPELP
141
KPSIS
146
SNNSN
151
PVEDK
156
DAVAF
161
TCEPE
166
TQDTT
171
YLWWI
176
NNQSL
181
PVSPR
186
LQLSN
191
GNRTL
196
TLLSV
201
TRNDT
206
GPYEC
211
EIQNP
216
VSANR
221
SDPVT
226
LNVTY
231
GPDTP
236
TISPS
241
DTYYR
246
PGANL
251
SLSCY
256
AASNP
261
PAQYS
266
WLING
271
TFQQS
276
TQELF
281
IPNIT
286
VNNSG
291
SYTCH
296
ANNSV
301
TGCNR
306
TTVKT
311
IIVTE
316
MAFHH
321
VAKAG
326
LKLLS
331
SSNPP
336
ASTSQ
341
SAKIT
346
DNALP
351
QENGL
356
SPGAI
361
AGIVI
366
GVVAL
371
VALIA
376
VALAC
381
FLHFG
386
KTGSS
391
GPLQ
396
Mutation Information
DNA mutation:
None
Peptide Range:
310 ~ 334
Mut AA position:
322 (13 in Wild Type peptide)
Alignment
Wild Type:
"RTTVKTIIVTEMAFHHVAKAGLKLL
||||||||||||.||||||||||||
Mutant:
RTTVKTIIVTEMGFHHVAKAGLKLL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000079385

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay