Immunogenicity 7251
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
FOXO3
Transcript ID
NM_001455
HLA INFO
C*03:04
TCR INFO
No TCR info found!
Full length protein sequence (673 aa)
MAEAP
1
ASPAP
6
LSPLE
11
VELDP
16
EFEPQ
21
SRPRS
26
CTWPL
31
QRPEL
36
QASPA
41
KPSGE
46
TAADS
51
MIPEE
56
EDDED
61
DEDGG
66
GRAGS
71
AMAIG
76
GGGGS
81
GTLGS
86
GLLLE
91
DSARV
96
LAPGG
101
QDPGS
106
GPATA
111
AGGLS
116
GGTQA
121
LLQPQ
126
QPLPP
131
PQPGA
136
AGGSG
141
QPRKC
146
SSRRN
151
AWGNL
156
SYADL
161
ITRAI
166
ESSPD
171
KRLTL
176
SQIYE
181
WMVRC
186
VPYFK
191
DKGDS
196
NSSAG
201
WKNSI
206
RHNLS
211
LHSRF
216
MRVQN
221
EGTGK
226
SSWWI
231
INPDG
236
GKSGK
241
APRRR
246
AVSMD
251
NSNKY
256
TKSRG
261
RAAKK
266
KAALQ
271
TAPES
276
ADDSP
281
SQLSK
286
WPGSP
291
TSRSS
296
DELDA
301
WTDFR
306
SRTNS
311
NASTV
316
SGRLS
321
PIMAS
326
TELDE
331
VQDDD
336
APLSP
341
MLYSS
346
SASLS
351
PSVSK
356
PCTVE
361
LPRLT
366
DMAGT
371
MNLND
376
GLTEN
381
LMDDL
386
LDNIT
391
LPPSQ
396
PSPTG
401
GLMQR
406
SSSFP
411
YTTKG
416
SGLGS
421
PTSSF
426
NSTVF
431
GPSSL
436
NSLRQ
441
SPMQT
446
IQENK
451
PATFS
456
SMSHY
461
GNQTL
466
QDLLT
471
SDSLS
476
HSDVM
481
MTQSD
486
PLMSQ
491
ASTAV
496
SAQNS
501
RRNVM
506
LRNDP
511
MMSFA
516
AQPNQ
521
GSLVN
526
QNLLH
531
HQHQT
536
QGALG
541
GSRAL
546
SNSVS
551
NMGLS
556
ESSSL
561
GSAKH
566
QQQSP
571
VSQSM
576
QTLSD
581
SLSGS
586
SLYST
591
SANLP
596
VMGHE
601
KFPSD
606
LDLDM
611
FNGSL
616
ECDME
621
SIIRS
626
ELMDA
631
DGLDF
636
NFDSL
641
ISTQN
646
VVGLN
651
VGNFT
656
GAKQA
661
SSQSW
666
VPG
671
Mutation Information
DNA mutation:
None
Peptide Range:
593 ~ 617
Mut AA position:
605 (13 in Wild Type peptide)
Alignment
Wild Type:
"YSTSANLPVMGHEKFPSDLDLDMFN
||||||||||||.||||||||||||
Mutant:
YSTSANLPVMGHDKFPSDLDLDMFN"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) FOXO3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay