Immunogenicity 7263
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ATM
Transcript ID
NM_000051
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO
No TCR info found!
Full length protein sequence (3056 aa)
MSLVL
1
NDLLI
6
CCRQL
11
EHDRA
16
TERKK
21
EVEKF
26
KRLIR
31
DPETI
36
KHLDR
41
HSDSK
46
QGKYL
51
NWDAV
56
FRFLQ
61
KYIQK
66
ETECL
71
RIAKP
76
NVSAS
81
TQASR
86
QKKMQ
91
EISSL
96
VKYFI
101
KCANR
106
RAPRL
111
KCQEL
116
LNYIM
121
DTVKD
126
SSNGA
131
IYGAD
136
CSNIL
141
LKDIL
146
SVRKY
151
WCEIS
156
QQQWL
161
ELFSV
166
YFRLY
171
LKPSQ
176
DVHRV
181
LVARI
186
IHAVT
191
KGCCS
196
QTDGL
201
NSKFL
206
DFFSK
211
AIQCA
216
RQEKS
221
SSGLN
226
HILAA
231
LTIFL
236
KTLAV
241
NFRIR
246
VCELG
251
DEILP
256
TLLYI
261
WTQHR
266
LNDSL
271
KEVII
276
ELFQL
281
QIYIH
286
HPKGA
291
KTQEK
296
GAYES
301
TKWRS
306
ILYNL
311
YDLLV
316
NEISH
321
IGSRG
326
KYSSG
331
FRNIA
336
VKENL
341
IELMA
346
DICHQ
351
VFNED
356
TRSLE
361
ISQSY
366
TTTQR
371
ESSDY
376
SVPCK
381
RKKIE
386
LGWEV
391
IKDHL
396
QKSQN
401
DFDLV
406
PWLQI
411
ATQLI
416
SKYPA
421
SLPNC
426
ELSPL
431
LMILS
436
QLLPQ
441
QRHGE
446
RTPYV
451
LRCLT
456
EVALC
461
QDKRS
466
NLESS
471
QKSDL
476
LKLWN
481
KIWCI
486
TFRGI
491
SSEQI
496
QAENF
501
GLLGA
506
IIQGS
511
LVEVD
516
REFWK
521
LFTGS
526
ACRPS
531
CPAVC
536
CLTLA
541
LTTSI
546
VPGTV
551
KMGIE
556
QNMCE
561
VNRSF
566
SLKES
571
IMKWL
576
LFYQL
581
EGDLE
586
NSTEV
591
PPILH
596
SNFPH
601
LVLEK
606
ILVSL
611
TMKNC
616
KAAMN
621
FFQSV
626
PECEH
631
HQKDK
636
EELSF
641
SEVEE
646
LFLQT
651
TFDKM
656
DFLTI
661
VRECG
666
IEKHQ
671
SSIGF
676
SVHQN
681
LKESL
686
DRCLL
691
GLSEQ
696
LLNNY
701
SSEIT
706
NSETL
711
VRCSR
716
LLVGV
721
LGCYC
726
YMGVI
731
AEEEA
736
YKSEL
741
FQKAK
746
SLMQC
751
AGESI
756
TLFKN
761
KTNEE
766
FRIGS
771
LRNMM
776
QLCTR
781
CLSNC
786
TKKSP
791
NKIAS
796
GFFLR
801
LLTSK
806
LMNDI
811
ADICK
816
SLASF
821
IKKPF
826
DRGEV
831
ESMED
836
DTNGN
841
LMEVE
846
DQSSM
851
NLFND
856
YPDSS
861
VSDAN
866
EPGES
871
QSTIG
876
AINPL
881
AEEYL
886
SKQDL
891
LFLDM
896
LKFLC
901
LCVTT
906
AQTNT
911
VSFRA
916
ADIRR
921
KLLML
926
IDSST
931
LEPTK
936
SLHLH
941
MYLML
946
LKELP
951
GEEYP
956
LPMED
961
VLELL
966
KPLSN
971
VCSLY
976
RRDQD
981
VCKTI
986
LNHVL
991
HVVKN
996
LGQSN
1001
MDSEN
1006
TRDAQ
1011
GQFLT
1016
VIGAF
1021
WHLTK
1026
ERKYI
1031
FSVRM
1036
ALVNC
1041
LKTLL
1046
EADPY
1051
SKWAI
1056
LNVMG
1061
KDFPV
1066
NEVFT
1071
QFLAD
1076
NHHQV
1081
RMLAA
1086
ESINR
1091
LFQDT
1096
KGDSS
1101
RLLKA
1106
LPLKL
1111
QQTAF
1116
ENAYL
1121
KAQEG
1126
MREMS
1131
HSAEN
1136
PETLD
1141
EIYNR
1146
KSVLL
1151
TLIAV
1156
VLSCS
1161
PICEK
1166
QALFA
1171
LCKSV
1176
KENGL
1181
EPHLV
1186
KKVLE
1191
KVSET
1196
FGYRR
1201
LEDFM
1206
ASHLD
1211
YLVLE
1216
WLNLQ
1221
DTEYN
1226
LSSFP
1231
FILLN
1236
YTNIE
1241
DFYRS
1246
CYKVL
1251
IPHLV
1256
IRSHF
1261
DEVKS
1266
IANQI
1271
QEDWK
1276
SLLTD
1281
CFPKI
1286
LVNIL
1291
PYFAY
1296
EGTRD
1301
SGMAQ
1306
QRETA
1311
TKVYD
1316
MLKSE
1321
NLLGK
1326
QIDHL
1331
FISNL
1336
PEIVV
1341
ELLMT
1346
LHEPA
1351
NSSAS
1356
QSTDL
1361
CDFSG
1366
DLDPA
1371
PNPPH
1376
FPSHV
1381
IKATF
1386
AYISN
1391
CHKTK
1396
LKSIL
1401
EILSK
1406
SPDSY
1411
QKILL
1416
AICEQ
1421
AAETN
1426
NVYKK
1431
HRILK
1436
IYHLF
1441
VSLLL
1446
KDIKS
1451
GLGGA
1456
WAFVL
1461
RDVIY
1466
TLIHY
1471
INQRP
1476
SCIMD
1481
VSLRS
1486
FSLCC
1491
DLLSQ
1496
VCQTA
1501
VTYCK
1506
DALEN
1511
HLHVI
1516
VGTLI
1521
PLVYE
1526
QVEVQ
1531
KQVLD
1536
LLKYL
1541
VIDNK
1546
DNENL
1551
YITIK
1556
LLDPF
1561
PDHVV
1566
FKDLR
1571
ITQQK
1576
IKYSR
1581
GPFSL
1586
LEEIN
1591
HFLSV
1596
SVYDA
1601
LPLTR
1606
LEGLK
1611
DLRRQ
1616
LELHK
1621
DQMVD
1626
IMRAS
1631
QDNPQ
1636
DGIMV
1641
KLVVN
1646
LLQLS
1651
KMAIN
1656
HTGEK
1661
EVLEA
1666
VGSCL
1671
GEVGP
1676
IDFST
1681
IAIQH
1686
SKDAS
1691
YTKAL
1696
KLFED
1701
KELQW
1706
TFIML
1711
TYLNN
1716
TLVED
1721
CVKVR
1726
SAAVT
1731
CLKNI
1736
LATKT
1741
GHSFW
1746
EIYKM
1751
TTDPM
1756
LAYLQ
1761
PFRTS
1766
RKKFL
1771
EVPRF
1776
DKENP
1781
FEGLD
1786
DINLW
1791
IPLSE
1796
NHDIW
1801
IKTLT
1806
CAFLD
1811
SGGTK
1816
CEILQ
1821
LLKPM
1826
CEVKT
1831
DFCQT
1836
VLPYL
1841
IHDIL
1846
LQDTN
1851
ESWRN
1856
LLSTH
1861
VQGFF
1866
TSCLR
1871
HFSQT
1876
SRSTT
1881
PANLD
1886
SESEH
1891
FFRCC
1896
LDKKS
1901
QRTML
1906
AVVDY
1911
MRRQK
1916
RPSSG
1921
TIFND
1926
AFWLD
1931
LNYLE
1936
VAKVA
1941
QSCAA
1946
HFTAL
1951
LYAEI
1956
YADKK
1961
SMDDQ
1966
EKRSL
1971
AFEEG
1976
SQSTT
1981
ISSLS
1986
EKSKE
1991
ETGIS
1996
LQDLL
2001
LEIYR
2006
SIGEP
2011
DSLYG
2016
CGGGK
2021
MLQPI
2026
TRLRT
2031
YEHEA
2036
MWGKA
2041
LVTYD
2046
LETAI
2051
PSSTR
2056
QAGII
2061
QALQN
2066
LGLCH
2071
ILSVY
2076
LKGLD
2081
YENKD
2086
WCPEL
2091
EELHY
2096
QAAWR
2101
NMQWD
2106
HCTSV
2111
SKEVE
2116
GTSYH
2121
ESLYN
2126
ALQSL
2131
RDREF
2136
STFYE
2141
SLKYA
2146
RVKEV
2151
EEMCK
2156
RSLES
2161
VYSLY
2166
PTLSR
2171
LQAIG
2176
ELESI
2181
GELFS
2186
RSVTH
2191
RQLSE
2196
VYIKW
2201
QKHSQ
2206
LLKDS
2211
DFSFQ
2216
EPIMA
2221
LRTVI
2226
LEILM
2231
EKEMD
2236
NSQRE
2241
CIKDI
2246
LTKHL
2251
VELSI
2256
LARTF
2261
KNTQL
2266
PERAI
2271
FQIKQ
2276
YNSVS
2281
CGVSE
2286
WQLEE
2291
AQVFW
2296
AKKEQ
2301
SLALS
2306
ILKQM
2311
IKKLD
2316
ASCAA
2321
NNPSL
2326
KLTYT
2331
ECLRV
2336
CGNWL
2341
AETCL
2346
ENPAV
2351
IMQTY
2356
LEKAV
2361
EVAGN
2366
YDGES
2371
SDELR
2376
NGKMK
2381
AFLSL
2386
ARFSD
2391
TQYQR
2396
IENYM
2401
KSSEF
2406
ENKQA
2411
LLKRA
2416
KEEVG
2421
LLREH
2426
KIQTN
2431
RYTVK
2436
VQREL
2441
ELDEL
2446
ALRAL
2451
KEDRK
2456
RFLCK
2461
AVENY
2466
INCLL
2471
SGEEH
2476
DMWVF
2481
RLCSL
2486
WLENS
2491
GVSEV
2496
NGMMK
2501
RDGMK
2506
IPTYK
2511
FLPLM
2516
YQLAA
2521
RMGTK
2526
MMGGL
2531
GFHEV
2536
LNNLI
2541
SRISM
2546
DHPHH
2551
TLFII
2556
LALAN
2561
ANRDE
2566
FLTKP
2571
EVARR
2576
SRITK
2581
NVPKQ
2586
SSQLD
2591
EDRTE
2596
AANRI
2601
ICTIR
2606
SRRPQ
2611
MVRSV
2616
EALCD
2621
AYIIL
2626
ANLDA
2631
TQWKT
2636
QRKGI
2641
NIPAD
2646
QPITK
2651
LKNLE
2656
DVVVP
2661
TMEIK
2666
VDHTG
2671
EYGNL
2676
VTIQS
2681
FKAEF
2686
RLAGG
2691
VNLPK
2696
IIDCV
2701
GSDGK
2706
ERRQL
2711
VKGRD
2716
DLRQD
2721
AVMQQ
2726
VFQMC
2731
NTLLQ
2736
RNTET
2741
RKRKL
2746
TICTY
2751
KVVPL
2756
SQRSG
2761
VLEWC
2766
TGTVP
2771
IGEFL
2776
VNNED
2781
GAHKR
2786
YRPND
2791
FSAFQ
2796
CQKKM
2801
MEVQK
2806
KSFEE
2811
KYEVF
2816
MDVCQ
2821
NFQPV
2826
FRYFC
2831
MEKFL
2836
DPAIW
2841
FEKRL
2846
AYTRS
2851
VATSS
2856
IVGYI
2861
LGLGD
2866
RHVQN
2871
ILINE
2876
QSAEL
2881
VHIDL
2886
GVAFE
2891
QGKIL
2896
PTPET
2901
VPFRL
2906
TRDIV
2911
DGMGI
2916
TGVEG
2921
VFRRC
2926
CEKTM
2931
EVMRN
2936
SQETL
2941
LTIVE
2946
VLLYD
2951
PLFDW
2956
TMNPL
2961
KALYL
2966
QQRPE
2971
DETEL
2976
HPTLN
2981
ADDQE
2986
CKRNL
2991
SDIDQ
2996
SFNKV
3001
AERVL
3006
MRLQE
3011
KLKGV
3016
EEGTV
3021
LSVGG
3026
QVNLL
3031
IQQAI
3036
DPKNL
3041
SRLFP
3046
GWKAW
3051
V
3056
Mutation Information
DNA mutation:
None
Peptide Range:
325 ~ 349
Mut AA position:
337 (13 in Wild Type peptide)
Alignment
Wild Type:
"HIGSRGKYSSGFRNIAVKENLIELM
||||||||||||.||||||||||||
Mutant:
HIGSRGKYSSGFHNIAVKENLIELM"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ATM
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay