Immunogenicity 7273

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HDAC9
Transcript ID
NM_001204147
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (513 aa)
MMMPV
1
VDPVV
6
REKQL
11
QQELL
16
LIQQQ
21
QQIQK
26
QLLIA
31
EFQKQ
36
HENLT
41
RQHQA
46
QLQEH
51
IKELL
56
AIKQQ
61
QELLE
66
KEQKL
71
EQQRQ
76
EQEVE
81
RHRRE
86
QQLPP
91
LRGKD
96
RGRER
101
AVAST
106
EVKQK
111
LQEFL
116
LSKSA
121
TKDTP
126
TNGKN
131
HSVSR
136
HPKLW
141
AAHHT
146
SLDQS
151
SPPLS
156
GTSPS
161
YKYTL
166
PGAQD
171
AKDDF
176
PLRKT
181
ESSVS
186
SSSPG
191
SGPSS
196
PNNGP
201
TGSVT
206
ENETS
211
VLPPT
216
PHAEQ
221
MVSQQ
226
RILIH
231
EDSMN
236
LLSLY
241
TSPSL
246
PNITL
251
GLPAV
256
PSQLN
261
ASNSL
266
KEKQK
271
CETQT
276
LRQGV
281
PLPGQ
286
YGGSI
291
PASSS
296
HPHVT
301
LEGKP
306
PNSSH
311
QALLQ
316
HLLLK
321
EQMRQ
326
QKLLV
331
AGGVP
336
LHPQS
341
PLATK
346
ERISP
351
GIRGT
356
HKLPR
361
HRPLN
366
RTQSA
371
PLPQS
376
TLAQL
381
VIQQQ
386
HQQFL
391
EKQKQ
396
YQQQI
401
HMNKL
406
LSKSI
411
EQLKQ
416
PGSHL
421
EEAEE
426
ELQGD
431
QAMQE
436
DRAPS
441
SGNST
446
RSDSS
451
ACVDD
456
TLGQV
461
GAVKV
466
KEEPV
471
DSDED
476
AQIQE
481
MESGE
486
QAAFM
491
QQVIG
496
KDLAP
501
GFVIK
506
VII
511
Mutation Information
DNA mutation:
None
Peptide Range:
128 ~ 152
Mut AA position:
140 (13 in Wild Type peptide)
Alignment
Wild Type:
"DTPTNGKNHSVSRHPKLWAAHHTSL
||||||||||||.||||||||||||
Mutant:
DTPTNGKNHSVSCHPKLWAAHHTSL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HDAC9

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay