Immunogenicity 7280
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PNPLA3
Transcript ID
NM_025225
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (481 aa)
MYDAE
1
RGWSL
6
SFAGC
11
GFLGF
16
YHVGA
21
TRCLS
26
EHAPH
31
LLRDA
36
RMLFG
41
ASAGA
46
LHCVG
51
VLSGI
56
PLEQT
61
LQVLS
66
DLVRK
71
ARSRN
76
IGIFH
81
PSFNL
86
SKFLR
91
QGLCK
96
CLPAN
101
VHQLI
106
SGKIG
111
ISLTR
116
VSDGE
121
NVLVS
126
DFRSK
131
DEVVD
136
ALVCS
141
CFIPF
146
YSGLI
151
PPSFR
156
GVRYV
161
DGGVS
166
DNVPF
171
IDAKT
176
TITVS
181
PFYGE
186
YDICP
191
KVKST
196
NFLHV
201
DITKL
206
SLRLC
211
TGNLY
216
LLSRA
221
FVPPD
226
LKVLG
231
EICLR
236
GYLDA
241
FRFLE
246
EKGIC
251
NRPQP
256
GLKSS
261
SEGMD
266
PEVAM
271
PSWAN
276
MSLDS
281
SPESA
286
ALAVR
291
LEGDE
296
LLDHL
301
RLSIL
306
PWDES
311
ILDTL
316
SPRLA
321
TALSE
326
EMKDK
331
GGYMS
336
KICNL
341
LPIRI
346
MSYVM
351
LPCTL
356
PVESA
361
IAIVQ
366
RLVTW
371
LPDMP
376
DDVLW
381
LQWVT
386
SQVFT
391
RVLMC
396
LLPAS
401
RSQMP
406
VSSQQ
411
ASPCT
416
PEQDW
421
PCWTP
426
CSPKG
431
CPAET
436
KAEAT
441
PRSIL
446
RSSLN
451
FFLGN
456
KVPAG
461
AEGLS
466
TFPSF
471
SLEKS
476
L
481
Mutation Information
DNA mutation:
None
Peptide Range:
159 ~ 183
Mut AA position:
171 (13 in Wild Type peptide)
Alignment
Wild Type:
"FRGVRYVDGGVSDNVPFIDAKTTIT
||||||||||||.||||||||||||
Mutant:
FRGVRYVDGGVSENVPFIDAKTTIT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PNPLA3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay