Immunogenicity 73
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TTC21B
Transcript ID
uc002udk.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1314 aa)
MDSQE
1
LKTLI
6
NYYCQ
11
ERYFH
16
HVLLV
21
ASEGI
26
KRYGS
31
DPVFR
36
FYHAY
41
GTLME
46
GKTQE
51
ALREF
56
EAIKN
61
KQDVS
66
LCSLL
71
ALIYA
76
HKMSP
81
NPDRE
86
AILES
91
DARVK
96
EQRKG
101
AGEKA
106
LYHAG
111
LFLWH
116
IGRHD
121
KAREY
126
IDRMI
131
KISDG
136
SKQGH
141
VLKAW
146
LDITR
151
GKEPY
156
TKKAL
161
KYFEE
166
GLQDG
171
NDTFA
176
LLGKA
181
QCLEM
186
RQNYS
191
GALET
196
VNQII
201
VNFPS
206
FLPAF
211
VKKMK
216
LQLAL
221
QDWDQ
226
TVETA
231
QRLLL
236
QDSQN
241
VEALR
246
MQALY
251
YVCRE
256
GDIEK
261
ASTKL
266
ENLGN
271
TLDAM
276
EPQNA
281
QLFYN
286
ITLAF
291
SRTCG
296
RSQLI
301
LQKIQ
306
TLLER
311
AFSLN
316
PQQSE
321
FATEL
326
GYQMI
331
LQGRV
336
KEALK
341
WYKTA
346
MTLDE
351
TSVSA
356
LVGFI
361
QCQLI
366
EGQLQ
371
DADQQ
376
LEFLN
381
EIQQS
386
IGKSA
391
ELIYL
396
HAVLA
401
MKKNK
406
RQEEV
411
INLLN
416
DVLDT
421
HFSQL
426
EGLPL
431
GIQYF
436
EKLNP
441
DFLLE
446
IVMEY
451
LSFCP
456
MQPAS
461
PGQPL
466
CPLLR
471
RCISV
476
LETVV
481
RTVPG
486
LLQTV
491
FLIAK
496
VKYLS
501
GDIEA
506
AFNNL
511
QHCLE
516
HNPSY
521
ADAHL
526
LLAQV
531
YLSQE
536
KVKLC
541
SQSLE
546
LCLSY
551
DFKVR
556
DYPLY
561
HLIKA
566
QSQKK
571
MGEIA
576
DAIKT
581
LHMAM
586
SLPGM
591
KRIGA
596
STKSK
601
DRKTE
606
VDTSH
611
RLSIF
616
LELID
621
VHRLN
626
GEQHE
631
ATKVL
636
QDAIH
641
EFSGT
646
SEEVR
651
VTIAN
656
ADLAL
661
AQGDI
666
ERALS
671
ILQNV
676
TAEQP
681
YFIEA
686
REKMA
691
DIYLK
696
HRKDK
701
MLYIT
706
CFREI
711
AERMA
716
NPRSF
721
LLLGD
726
AYMNI
731
LEPEE
736
AIVAY
741
EQALN
746
QNPKD
751
GTLAS
756
KMGKA
761
LIKTH
766
NYSMA
771
ITYYE
776
AALKT
781
GQKNY
786
LCYDL
791
AELLL
796
KLKWY
801
DKAEK
806
VLQHA
811
LAHEP
816
VNELS
821
ALMED
826
GRCQV
831
LLAKV
836
YSKME
841
KLGDA
846
ITALQ
851
QAREL
856
QARVL
861
KRVQM
866
EQPDA
871
VPAQK
876
HLAAE
881
ICAEI
886
AKHSV
891
AQRDY
896
EKAIK
901
FYREA
906
LVHCE
911
TDNKI
916
MLELA
921
RLYLA
926
QDDPD
931
SCLRQ
936
CALLL
941
QSDQD
946
NEAAT
951
MMMAD
956
LMFRK
961
QDYEQ
966
AVFHL
971
QQLLE
976
RKPDN
981
YMTLS
986
RLIDL
991
LRRCG
996
KLEDV
1001
PRFFS
1006
MAEKR
1011
NSRAK
1016
LEPGF
1021
QYCKG
1026
LYLWY
1031
TGEPN
1036
DALRH
1041
FNKAR
1046
KDRDW
1051
GQNAL
1056
YNMIE
1061
ICLNP
1066
DNETV
1071
GGEVF
1076
ENLDG
1081
DLGNS
1086
TEKQE
1091
SVQLA
1096
VRTAE
1101
KLLKE
1106
LKPQT
1111
VQGHV
1116
QLRIM
1121
ENYCL
1126
MATKQ
1131
KSNVE
1136
QALNT
1141
FTEIA
1146
ASEKE
1151
HIPAL
1156
LGMAT
1161
AYMIL
1166
KQTPR
1171
ARNQL
1176
KRIAK
1181
MNWNA
1186
IDAEE
1191
FEKSW
1196
LLLAD
1201
IYIQS
1206
AKYDM
1211
AEDLL
1216
KRCLR
1221
HNRSC
1226
CKAYE
1231
YMGYI
1236
MEKEQ
1241
AYTDA
1246
ALNYE
1251
MAWKY
1256
SNRTN
1261
PAVDH
1266
DPLNC
1271
NLQSC
1276
VLGLV
1281
FKPSA
1286
VTCPF
1291
FLRLD
1296
SESLI
1301
FLVAV
1306
SWKL
1311
Mutation Information
DNA mutation:
c.G3305A
Peptide Range:
1090 ~ 1114
Mut AA position:
1102 (13 in Wild Type peptide)
Alignment
Wild Type:
"STEKQESVQLAVRTAEKLLKELKPQ
||||||||||||.||||||||||||
Mutant:
STEKQESVQLAVKTAEKLLKELKPQ"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TTC21B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
STEKQESVQLAVKTAEKLLKELKPQ
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT