Immunogenicity 7319

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CDH10
Transcript ID
NM_006727
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (788 aa)
MTIHQ
1
FLLLF
6
LFWVC
11
LPHFC
16
SPEIM
21
FRRTP
26
VPQQR
31
ILSSR
36
VPRSD
41
GKILH
46
RQKRG
51
WMWNQ
56
FFLLE
61
EYTGS
66
DYQYV
71
GKLHS
76
DQDKG
81
DGSLK
86
YILSG
91
DGAGT
96
LFIID
101
EKTGD
106
IHATR
111
RIDRE
116
EKAFY
121
TLRAQ
126
AINRR
131
TLRPV
136
EPESE
141
FVIKI
146
HDIND
151
NEPTF
156
PEEIY
161
TASVP
166
EMSVV
171
GTSVV
176
QVTAT
181
DADDP
186
SYGNS
191
ARVIY
196
SILQG
201
QPYFS
206
VEPET
211
GIIRT
216
ALPNM
221
NRENR
226
EQYQV
231
VIQAK
236
DMGGQ
241
MGGLS
246
GTTTV
251
NITLT
256
DVNDN
261
PPRFP
266
QNTIH
271
LRVLE
276
SSPVG
281
TAIGS
286
VKATD
291
ADTGK
296
NAEVE
301
YRIID
306
GDGTD
311
MFDIV
316
TEKDT
321
QEGII
326
TVKKP
331
LDYES
336
RRLYT
341
LKVEA
346
ENTHV
351
DPRFY
356
YLGPF
361
KDTTI
366
VKISI
371
EDVDE
376
PPVFS
381
RSSYL
386
FEVHE
391
DIEVG
396
TIIGT
401
VMARD
406
PDSIS
411
SPIRF
416
SLDRH
421
TDLDR
426
IFNIH
431
SGNGS
436
LYTSK
441
PLDRE
446
LSQWH
451
NLTVI
456
AAEIN
461
NPKET
466
TRVAV
471
FVRIL
476
DVNDN
481
APQFA
486
VFYDT
491
FVCEN
496
ARPGQ
501
LIQTI
506
SAVDK
511
DDPLG
516
GQKFF
521
FSLAA
526
VNPNF
531
TVQDN
536
EDNTA
541
RILTR
546
KNGFN
551
RHEIS
556
TYLLP
561
VVISD
566
NDYPI
571
QSSTG
576
TLTIR
581
VCACD
586
SQGNM
591
QSCSA
596
EALLL
601
PAGLS
606
TGALI
611
AILLC
616
IIILL
621
VIVVL
626
FAALK
631
RQRKK
636
EPLIL
641
SKEDI
646
RDNIV
651
SYNDE
656
GGGEE
661
DTQAF
666
DIGTL
671
RNPAA
676
IEEKK
681
LRRDI
686
IPETL
691
FIPRR
696
TPTAP
701
DNTDV
706
RDFIN
711
ERLKE
716
HDLDP
721
TAPPY
726
DSLAT
731
YAYEG
736
NDSIA
741
ESLSS
746
LESGT
751
TEGDQ
756
NYDYL
761
REWGP
766
RFNKL
771
AEMYG
776
GGESD
781
KDS
786
Mutation Information
DNA mutation:
None
Peptide Range:
253 ~ 277
Mut AA position:
265 (13 in Wild Type peptide)
Alignment
Wild Type:
"TTVNITLTDVNDNPPRFPQNTIHLR
||||||||||||.||||||||||||
Mutant:
TTVNITLTDVNDKPPRFPQNTIHLR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CDH10

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay